iFIT Lunch & Learn Session with Dr. Christian Schmees
Patient-derived microtumors - Exploring biology and application for preclinical drug development and personalized medicine
On behalf of the iFIT spokespersons Lars Zender, Hans-Georg Rammensee and Bernd Pichler, it is our pleasure to inform you about and invite you to the next episode of our iFIT Seminar Series 2023 that will take place
on Monday, July 17th at 12:00 pm s.t. (CEST)
at Crona HS 210 (Crona Kliniken, Hoppe-Seyler-Straße 3, 72076 Tübingen).
Our guest speaker Dr. Christian Schmees from NMI Natural and Medical Sciences Institute at the University of Tübingen will give a talk on
“Patient-derived microtumors - Exploring biology and application for preclinical drug development and personalized medicine”.
“In the era of personalized medicine, the ability of pre-selecting individualized therapeutic options and pre-defining their suitability in advance of clinical treatment might facilitate decision making in cancer therapy and hence, improve patient outcome. At the same time, it is crucial to design a model system that reflects the influence of the tumor microenvironment and cellular heterogeneity on drug response in order to preclinically validate anti-cancer drug efficacy, we have established a 3D model system comprised of patient-derived microtumors (PDM), and autologous tumor-infiltrated lymphocytes (TIL) from a variety of solid cancer types that can be subjected to downstream analyses within 2-3 days after isolation and is free from animal components. In my talk I will present data from histological and immunohistochemical as well as protein signaling pathway characterization of PDM in comparison to corresponding primary tumor tissue. Moreover, I will summarize results from compound efficacy testing assays and immunophenotyping analyses of PDM cultures in the presence and absence of autologous TIL populations.”
As a special feature of this program, the iFIT will sponsor free lunch packages! (First come, first serve)
All members of the University Hospital and University of Tübingen are invited to participate!
We look forward to this Lunch & Learn session and to see you there!
