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Research group "Cell division control"

Head of the research group


Prof. Dr. med. Nisar Malek
Tel. +49 7071 29-82722
Fax +49 7071 29-22095


The focus of the work in our group is the research of cell division mechanisms, especially with respect to the formation of malignant tumours. The goal is to decode the critical molecular mechanisms for the formation of tumours and to enable them to be used for a therapeutic intervention. In addition to basic scientific considerations, we are therefore very interested in transferring our findings to new methods of treatment as well. For processing our projects, we use mouse models and high throughput screening along with cellular and molecular biology techniques for identifying new substance candidates.


Here you can find the membes of our research group

Team members (German language)

Selected publications
  • Serres, M. P., Kossatz, U., Chi, Y., Roberts, J. M., Malek, N. P., and Besson, A. (2012) J Clin Invest 122, 844-858
  • Puklowski, A., Homsi, Y., Keller, D., May, M., Chauhan, S., Kossatz, U., Grunwald, V., Kubicka, S., Pich, A., Manns, M. P., Hoffmann, I., Gonczy, P., and Malek, N. P. (2011) Nat Cell Biol 13, 1004-1009
  • Kossatz, U., Breuhahn, K., Wolf, B., Hardtke-Wolenski, M., Wilkens, L., Steinemann, D., Singer, S., Brass, F., Kubicka, S., Schlegelberger, B., Schirmacher, P., Manns, M. P., Singer, J. D., and Malek, N. P. (2010) J Clin Invest 120, 3820-3833
  • Nickeleit, I., Zender, S., Sasse, F., Geffers, R., Brandes, G., Sorensen, I., Steinmetz, H., Kubicka, S., Carlomagno, T., Menche, D., Gutgemann, I., Buer, J., Gossler, A., Manns, M. P., Kalesse, M., Frank, R., and Malek, N. P. (2008) Cancer Cell 14, 23-35


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Research Group "Cell division control"
Otfried-Müller-Straße 10
72076 Tübingen
Dr. Uta Kossatz-Böhlert
Tel. +49 7071 29-83137
Fax +49 7071 29-4680

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