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Translational Psychiatry

The research of the Section Translational Psychiatry focusses on neurological characteristics of affective disorders, mainly on depression.
We try to shed light on all aspects and manifestations of the disease, by means of different neuroimaging methods.

 

To our projects

Head of Research Group and Members

Martin Walter

Prof. Dr. Martin Walter (Head)

 

Tel. +49 7071 29-86119 (Secretary: Helga Lennig )

 

 

 
 

helga_lennig_60x60

Helga Lennig
Secretary
Tel. +49 7071 29-86119

 

 

 
 

Luisa Fensky

Luisa Fensky
Scientific Coordinator
Tel. +49 7071 29-85753

 

 

 
 

Nils Kroemer

Dr. Nils Krömer
Junior Research Group Leader
Tel. +49 7071 29-82021

 

 

 
 

Johan van der Meer

Dr. Johan van der Meer
Postdoc

 

 

 
 

Meng Li

Dr. Meng Li
Postdoc

 

 

 
 

Sarah Alizadeh

Sarah Alizadeh
Research associate
Tel. +49 7071 29-82034

 

 

 
 

Hamidreza Jamalabadi

Hamidreza Jamalabadi
Research associate
Tel. +49 7071 29-82034

 

 

 
 

Vanessa Teckentrupp

Vanessa Teckentrup
Ph.D. candidate
Tel. +49 7071 29-85753

 

 

 
 

Tara Chand

Tara Chand
Ph.D. candidate
Tel. +49 7071 29-82086

 

 

 
 

Louise Martens

Louise Martens
Ph.D. candidate
Tel. +49 7071 29-82086

 

 

 
 

Marina Krylova

Marina Krylova
Ph.D. candidate
Tel. +49 7071 29-82086

 

 

 
 

Lena Danyeli

Lena Danyeli
Ph.D. candidate
Tel. +49 7071 29-82086

 
 

 

 
 

Galina Surova

Galina Surova
Ph.D. candidate
Tel. +49 7071 29-82086

 

 

 
 

Zumrut Duygusen

Zumrut Duygusen
Research associate

 

 

 
 

Igor Izyurov

Igor Izyurov
Research associate

 

 

 
 

Maryam Faramarzi

Maryam Faramarzi
Research associate

 

 

 
 

Kathrin Meyer

Kathrin Meyer
MD-Ph.D. candidate

 

 

 
 

Greta Amedick

Greta Amedick
MD-Ph.D. candidate

 

 

 
 

Alex Shevtsova

Alex Shevtsova
Master student

 

 

 
 

Merve Kaptan

Merve Kaptan
Master student

 

 

 
 

Monja Neuser

Monja Neuser
Master student, Student assistant

 

 

 
 

Dina Lausch

Dina Lausch
Student assistant

 

 

 
 

Rahel Gutbrod

Rahel Gutbrod
Student assistant

 

 

Associated Research Groups
projects

 

 

Resting-state Dynamics and their changes in depressed patients

 

Interaction of resting state dynamics of connectivity and other state markers of the autonomous nervous system

(Collaboration with Catherine E. Chang, Stanford, CA)

 

 

Influence of structural changes in healthy subjects and depression

 

Use of DTI and cortical thickness measurements, including longitudinal observations at different field strengths, to generate a link of abnormal structural, histological, functional, and metabolic evidence in depression

 

 

Metabolism-BOLD-interaction during task- and resting-state fMRI

 

Combinations of Magnetic Resonance Spectroscopy (MRS) and fMRI from 3T to 7T for GABA, Glutamate or Glutamine

 

 

Non-invasive interventions and neurofeedback

 

Usage of parallel real-time EEG-fMRI for the induction of altered brain states by specific manipulation of subnetworks; The use of EMG signatures of mimic expressions as alternative treatment options to psychotherapy and neuropsychopharmacology

 

 

Abnormal brain network behavior in major depression

 

Investigation of the pathological processing of internal and external stimuli in affective disorders based on alterations of the functional brain network
(collaboration with Michael Breakspear, Brisbane, Queensland, Australia)

 

 

Network alterationsunder orally antidepressant treatment

 

Analyses of functional activations and connectivity of data containing pharmacological challenges for the investigation of neurobiological differences on a circuit level
(Collaboration with Birgit Abler und Heiko Graf, University of Ulm)

 

 

Investigation of pharmacological side effects and their prediction by passive MRI assessment

 

Identification of brain biomarkers from resting state fMRI which can reveal information about a patients individual vulnerability to develop certain side effects even before initiation of pharmacotherapy

 

 

Expectancy, recollection and perception of affective stimuli in major depression

 

Investigations on which brain networks, either by integration or in interaction with other functional systems, are involved in the development of the system

 

 

Resting-state alterations by visual salient stimulation in fMRI and EEG

 

Application of parallel EEG fMRI to discern sub-processes of mutual cognitive-affective regulation using erotic stimuli
(Collaboration with Harold Mouras, Amiens, France)

 

 

High-field fMRI of thalamo-cortical circuits

 

Measurement of the specificity of the nuclear subunits in thalamus and basal ganglia; Investigation of the cortico-striatal-thalamo-cortical loop relevant for cognitive and affective processing

 

 

Ketamine in treatment resistant depression

 

In addition, the results of the study of NMDA antagonists

 

 

Optimization of image acquisition and processing for large scale data

 

Determination of optimized and standardized imaging protocols for data quality and robust control of potential confounders; Development of methods and methods for the assessment of the effects of the disease on the immune system






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