We have the unique possibility for superresolution live cell imaging in our BSL-3 lab. We use the General Electric Delta Vision OMX SR microscope. With this cutting-edge technology we can resolve structures with a size down to 100 nm or even less under certain conditions. Therefore, we have the precious opportunity to image single virions and their subcellular movement.
Imaging viral infections
Some technical details:
- Live cell imaging 3D structured illumination microscopy (3D-SIM)
- Total internal reflection fluorescence microscopy
- TIRF and 3D-SIM in combination with fluorescence recovery after photobleaching
- Ultra-high speed fluorescence live cell imaging with deconvolution
- Hardware-based autofocus system
- 2 sCMOS cameras
- 4 lasers (405, 488, 568, 640)
Presentation (kindly provided by Daniel White, application specialist GE)
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