New research on the NLRP3 Inflammasome

New research on the NLRP3 Inflammasome just out as a Biorxiv preprint, showing an unexpected negative regulatory role for Bruton's tyrosine kinase (BTK) for IL-1 and NET release. Interestingly, FDA-approved BTK inhibitors thus boost these pro-inflammatory functions https://www.biorxiv.org/content/10.1101/2024.02.23.581733v1