Beitrag

05.12.2023

Gene Therapy Trial for Hearing Loss

The group of Profesor Ellen Reisinger developed a dual-AAV gene supplementation with the cDNA for otoferlin, a protein encoded by the gene OTOF. It is supposed to restore hearing in patients with OTOF mutations, DFNB9.

The company "Akouos Inc." started a clinical trial15th of September 2023:

https://www.clinicaltrials.gov/study/NCT05821959?cond=Hearing%20Loss&term=OTOF&intr=gene%20therapy&rank=3