Our research focuses on the function and regulation of control processes (signal transduction) of cells, tissues and organs. We are particularly interested in pharmacological intervention options for metabolic dysfunctions (obesity, diabetes mellitus types I and II), cardiovascular diseases, immunological defense processes and pain.
DFG Research Training Group GRK 2816/1
Learn moreThe Interfaculty Centre for Pharmacogenomics and Pharma Research is a joint scientific institution of the
Beer-Hammer S., Lee S.C., Mauriac S.A., Leiss V., Groh I.A.M., Novakovic A., Piekorz R.P., Bucher K., Chen C., Ni K., Singer W., Harasztosi C., Schimmang T., Zimmermann U., Pfeffer K., Birnbaumer L., Forge A., Montcouquiol M., Knipper M., Nürnberg B., Rüttiger L. (2018): Gαi proteins are indispensable for hearing. Cell. Physiol. Biochem. 47, 1509-1532
Mauriac S.A., Hien E.Y., Bird J., Dos‐Santos Carvalho S., Peyroutou R., Lee S.C., Moreau M.M., Blanc J.-M., Geyser A., Medina C., Thoumine O., Beer‐Hammer S., Friedman T., Rüttiger L., Forge A., Nürnberg B., Sans N., Montcouquiol M. (2017): Defective Gpsm2/Gαi3 signaling disrupts stereocilia development and growth cone actin dynamics in Chudley McCullough syndrome. Nat. Commun. 2017 Apr 7; 8:14907. doi: 10.1038/ncomms14907
Devanathan V., Hagedorn I., Köhler D., Pexa K., Cherpokova D., Kraft P., Singh M., Rosenberger P., Stoll G., Birnbaumer L., Piekorz R., Beer-Hammer S., Nieswandt B., Nürnberg B. (2015): Platelet Gαi2 is an essential mediator of thrombo-inflammatory organ damage in mice. Proc. Natl. Acad. Sci. USA 112, 6491-6496
Vadas O., Dbouk H.A., Shymanets A., Perisic O., Burke J.E., Khalil B.D., Ohashi M., Harteneck C., Nürnberg B., Backer J.M., Williams R.L. (2013): Molecular determinants of PI3Kg-mediated activation downstream of GPCRs. Proc. Natl. Acad. Sci. USA 110, 18862-18867
Kurig B., Shymanets A., Bohnacker T., Prajwal, Brock C., Ahmadian M.R., Schaefer M., Gohla A., Harteneck C., Wymann M.P., Jeanclos E., Nürnberg B. (2009): Ras is an indispensable coregulator of the class IB phosphoinositide 3-kinase p87/p110γ. Proc. Natl. Acad. Sci. USA 106, 20312-20317
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Kooperation für Transparenz und Qualität im Gesundheitswesen
Qualitätspartnerschaft mit der PKV
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Die Altersvorsorge für den Öffentlichen Dienst
