Pharmakologie, Experimentelle Therapie und Toxikologie
Department für Experimentelle und Klinische Pharmakologie und Pharmakogenomik

Ausgewählte Publikationen

• Beer-Hammer S., Lee S.C., Mauriac S.A., Leiss V., Groh I.A.M., Novakovic A., Piekorz R.P., Bucher K., Chen C., Ni K., Singer W., Harasztosi C., Schimmang T., Zimmermann U., Pfeffer K., Birnbaumer L., Forge A., Montcouquiol M., Knipper M., Nürnberg B., Rüttiger L. (2018): Gαi proteins are indispensable for hearing. Cell. Physiol. Biochem. 47, 1509-1532

• Mauriac S.A., Hien E.Y., Bird J., Dos‐Santos Carvalho S., Peyroutou R., Lee S.C., Moreau M.M., Blanc J.-M., Geyser A., Medina C., Thoumine O., Beer‐Hammer S., Friedman T., Rüttiger L., Forge A., Nürnberg B., Sans N., Montcouquiol M. (2017): Defective Gpsm2/Gαi3 signaling disrupts stereocilia development and growth cone actin dynamics in Chudley McCullough syndrome. Nat. Commun. 2017 Apr 7; 8:14907. doi: 10.1038/ncomms14907

• Devanathan V., Hagedorn I., Köhler D., Pexa K., Cherpokova D., Kraft P., Singh M., Rosenberger P., Stoll G., Birnbaumer L., Piekorz R., Beer-Hammer S., Nieswandt B., Nürnberg B. (2015): Platelet Gαi2 is an essential mediator of thrombo-inflammatory organ damage in mice. Proc. Natl. Acad. Sci. USA 112, 6491-6496

• Vadas O., Dbouk H.A., Shymanets A., Perisic O., Burke J.E., Khalil B.D., Ohashi M., Harteneck C., Nürnberg B., Backer J.M., Williams R.L. (2013): Molecular determinants of PI3Kg-mediated activation downstream of GPCRs. Proc. Natl. Acad. Sci. USA 110, 18862-18867

• Kurig B., Shymanets A., Bohnacker T., Prajwal, Brock C., Ahmadian M.R., Schaefer M., Gohla A., Harteneck C., Wymann M.P., Jeanclos E., Nürnberg B. (2009): Ras is an indispensable coregulator of the class IB phosphoinositide 3-kinase p87/p110γ. Proc. Natl. Acad. Sci. USA 106, 20312-20317