Kocherscheidt L, Flakowski A-K, Grüner B, Hamm DM, Dietz K, Kern P, Soboslay PT. abstract Echinococcus multilocularis: Inflammatory and regulatory chemokine responses in patients with progressive, stable and cured alveolar echinococcosis. Exp. Parasitol. 2008; 119(8): 467-74 Duerr HP, Hoffmann W, Eichner M. abstract Does resistance to filarial reinfection become leaky over time? Trends in Parasitology 2008; 24(8): 350-4 Knopp S, Amegbo IK, Hamm DM, Schulz-Key H, Banla M, Soboslay PT. abstract Antibody and cytokine responses in Dracunculus medinensis patients at distinct states of infection. Trans R Soc Trop Med Hyg. 2008;102(3):277-83 Hübner MP, Pasche B, Kalaydjiev S, Soboslay PT, Lengeling A, Schulz-Key H, Mitre E, Hoffmann WH. abstract Microfilariae of the filarial nematode Litomosoides sigmodontis exacerbate the course of LPS-induced sepsis in mice. Infect Immun. 2008; 76(4) 1668-77 Dittrich AM, Erbacher A, Specht S, Diesner F, Krokowski M, Avagyan A, Stock P, Ahrens B, Hoffmann WH, Hoerauf A, Hamelmann E. abstract Litomosoides sigmodontis Induces Regulatory T Cells and Inhibits Allergic Sensitization, Airway Inflammation, and Hyperreactivity in a Murine Asthma Model. J Immunol 2008; 180(3):1792-9

Mai C, Hamm DM, Banla M, Agossou A, Schulz-Key H, Heuschkel C, Soboslay PT. abstract Onchocerca volvulus-specific antibody and cytokine responses in onchocerciasis patients after 16 years of repeated ivermectin therapy. Clin Exp Immunol. 2007;147(3):504–512

Hübner MP, Manfras BJ, Margos MC, Eiffler D, Hoffmann WH, Schulz-Key H, Kern P, Soboslay PT. abstract Echinococcus multilocularis metacestodes modulate cellular cytokine and chemokine release by peripheral blood mononuclear cells in alveolar echinococcosis patients. Clin Exp Immunol. 2006;145(2):243-251

Soboslay PT, Hamm DM, Pfäfflin F, Fendt J, Banla M, Schulz-Key H. abstract Cytokine and chemokine responses in patients co-infected with Entamoeba histolytica/dispar, Necator americanus and Mansonella perstans and changes after anti-parasite treatment. Microbes Infect. 2006;8:238-247 Fendt J, Hamm DM, Banla M, Schulz-Key H, Wolf H, Helling-Giese G, Heuschkel C, Soboslay PT. abstract Chemokines in onchocerciasis patients after a single dose of ivermectin. Clin Exp Immunol. 2005;142:318-326

Abrahams-Sandi E, Hoffmann WH, Graeff-Teixeira C, Schulz-Key H, Geiger SM. abstract Long-term observations on mouse strains experimentally infected with Angiostrongylus costaricensis. Parasitol Res. 2004 Jun;93(3):230-4. Geiger SM, Massara CL, Bethony J, Soboslay PT, Correa-Oliveira R. abstract Cellular responses and cytokine production in post-treatment hookworm patients from an endemic area in Brazil. Clin Exp Immunol. 2004 May;136(2):334-40. Kirch AK, Agossou A, Banla M, Hoffmann WH, Schulz-Key H, Soboslay PT abstract Parasite-specific antibody and cytokine profiles in newborns from Plasmodium falciparum and Entamoeba histolytica/dispar-infected mothers. Pediatr Allergy Immunol. 2004 Apr;15(2):133-41. Duerr HP, Dietz K, Schulz-Key H, Buttner DW, Eichner M. abstract The relationships between the burden of adult parasites, host age and the microfilarial density in human onchocerciasis. Int J Parasitol. 2004 Mar 29;34(4):463-73.

Kirch AK, Duerr HP, Boatin B, Alley WS, Hoffmann WH, Schulz-Key H, Soboslay PT. abstract Impact of parental onchocerciasis and intensity of transmission on development and persistence of Onchocerca volvulus infection in offspring: an 18 year follow-up study. Parasitology. 2003 Oct;127(Pt 4):327-35. Pfaff AW, Kirch AK, Hoffmann WH, Banla M, Schulz-Key H, Geiger SM, Soboslay PT. abstract Regulatory effects of IL-12 and IL-18 on Onchocerca volvulus- and Entamoeba histolytica-specific cellular reactivity and cytokine profiles. Parasite Immunol. 2003 Jun;25(6):325-32. Duerr HP, Dietz K, Schulz-Key H, Buttner DW, Eichner M. abstract Density-dependent parasite establishment suggests infection-associated immunosuppression as an important mechanism for parasite density regulation in onchocerciasis. Trans R Soc Trop Med Hyg. 2003 Mar-Apr;97(2):242-50. Eger A, Kirch A, Manfras B, Kern P, Schulz-Key H, Soboslay PT. abstract Pro-inflammatory (IL-1beta, IL-18) cytokines and IL-8 chemokine release by PBMC in response to Echinococcus multilocularis metacestode vesicles. Parasite Immunol. 2003 Feb;25(2):103-5. Geiger SM, Hoffmann WH, Soboslay PT, Pfaff AW, Graeff-Teixeira C, Schulz-Key H. abstract Angiostrongylus costaricensis infection in C57BL/6 mice: MHC-II deficiency results in increased larval elimination but unaltered mortality. Parasitol Res. 2003 Aug;90(5):415-20. Epub 2003 May 16. Banla M, Balo KP, Soboslay P, Meda DN, Ouro Djeri S. abstract Corneal perforated wounds treatment by "thermal contact": report of 25 cases Dakar Med. 2003;48(2):134-7. French.

Geiger SM, Massara CL, Bethony J, Soboslay PT, Carvalho OS, Correa-Oliveira R. abstract Cellular responses and cytokine profiles in Ascaris lumbricoides and Trichuris trichiura infected patients. Parasite Immunol. 2002 Nov-Dec;24(11-12):499-509. Pfaff AW, Schulz-Key H, Soboslay PT, Taylor DW, MacLennan K, Hoffmann WH. abstract Litomosoides sigmodontis cystatin acts as an immunomodulator during experimental filariasis. Int J Parasitol. 2002 Feb;32(2):171-8.

Pit DS, Polderman AM, Baeta S, Schulz-Key H, Soboslay PT. abstract Parasite-specific antibody and cellular immune responses in human infected with Necator americanus and Oesophagostomum bifurcum. Parasitol Res. 2001 Sep;87(9):722-9. Geiger SM, Abrahams-Sandi E, Soboslay PT, Hoffmann WH, Pfaff AW, Graeff-Teixeira C, Schulz-Key H. abstract Cellular immune responses and cytokine production in BALB/c and C57BL/6 mice during the acute phase of Angiostrongylus costaricensis infection. Acta Trop. 2001 Sep 1;80(1):59-68. Duerr HP, Dietz K, Buttner DW, Schulz-Key H. abstract A stochastic model for the aggregation of Onchocerca volvulus in nodules. Parasitology. 2001 Aug;123(Pt 2):193-201. Hoffmann WH, Pfaff AW, Schulz-Key H, Soboslay PT. abstract Determinants for resistance and susceptibility to microfilaraemia in Litomosoides sigmodontis filariasis. Parasitology. 2001 Jun;122(Pt 6):641-9. Erratum in: Parasitology 2001 Sep;123(Pt 3):234. Soboslav PT [corrected to Soboslay PT]. Geiger SM, Laitano AC, Sievers-Tostes C, Agostini AA, Schulz-Key H, Graeff-Teixeira C. abstract Detection of the acute phase of abdominal angiostrongyliasis with a parasite-specific IgG enzyme linked immunosorbent assay. Mem Inst Oswaldo Cruz. 2001 May;96(4):515-8.

Hoffmann W, Petit G, Schulz-Key H, Taylor D, Bain O, Le Goff L. abstract Litomosoides sigmodontis in mice: reappraisal of an old model for filarial research. Parasitol Today. 2000 Sep;16(9):387-9. Review. Pfaff AW, Schulz-Key H, Soboslay PT, Geiger SM, Hoffmann WH. abstract The role of nitric oxide in the innate resistance to microfilariae of Litomosoides sigmodontis in mice. Parasite Immunol. 2000 Aug;22(8):397-405. Pit DS, Polderman AM, Schulz-Key H, Soboslay PT. abstract Prenatal immune priming with helminth infections: parasite-specific cellular reactivity and Th1 and Th2 cytokine responses in neonates. Allergy. 2000 Aug;55(8):732-9. Wuhrer M, Rickhoff S, Dennis RD, Lochnit G, Soboslay PT, Baumeister S, Geyer R. abstract Phosphocholine-containing, zwitterionic glycosphingolipids of adult Onchocerca volvulus as highly conserved antigenic structures of parasitic nematodes. Biochem J. 2000 Jun 1;348 Pt 2:417-23. Pfaff AW, Schulz-Key H, Soboslay PT, Geiger SM, Hoffmann WH. abstract Litomosoides sigmodontis: dynamics of the survival of microfilariae in resistant and susceptible strains of mice. Exp Parasitol. 2000 Feb;94(2):67-74.

Graeff-Teixeira C, Geiger S, Walderich B, Hoffmann W, Abrahams E, Schulz-Key H. abstract Isolation of Angiostrongylus costaricensis first-stage larvae from rodent feces on a Percoll gradient. J Parasitol. 1999 Dec;85(6):1170-1. Soboslay PT, Luder CG, Riesch S, Geiger SM, Banla M, Batchassi E, Stadler A, Schulz-Key H. abstract Regulatory effects of Th1-type (IFN-gamma, IL-12) and Th2-type cytokines (IL-10, IL-13) on parasite-specific cellular responsiveness in Onchocerca volvulus-infected humans and exposed endemic controls. Immunology. 1999 Jun;97(2):219-25. Dreweck CM, Soboslay PT, Schulz-Key H, Gottstein B, Kern P. abstract Cytokine and chemokine secretion by human peripheral blood cells in response to viable Echinococcus multilocularis metacestode vesicles. Parasite Immunol. 1999 Aug;21(8):433-8. Soboslay PT, Geiger SM, Drabner B, Banla M, Batchassi E, Kowu LA, Stadler A, Schulz-Key H. abstract Prenatal immune priming in onchocerciasis-onchocerca volvulus-specific cellular responsiveness and cytokine production in newborns from infected mothers. Clin Exp Immunol. 1999 Jul;117(1):130-7. Geiger SM, Graeff-Teixeira C, Soboslay PT, Schulz-Key H. abstract Experimental Angiostrongylus costaricensis infection in mice: immunoglobulin isotype responses and parasite-specific antigen recognition after primary low-dose infection. Parasitol Res. 1999 Mar;85(3):200-5.

Kwa MS, Okoli MN, Schulz-Key H, Okongkwo PO, Roos MH. abstract Use of P-glycoprotein gene probes to investigate anthelmintic resistance in Haemonchus contortus and comparison with Onchocerca volvulus. Int J Parasitol. 1998 Aug;28(8):1235-40.

Dreweck CM, Luder CG, Soboslay PT, Kern P. abstract Subclass-specific serological reactivity and IgG4-specific antigen recognition in human echinococcosis. Trop Med Int Health. 1997 Aug;2(8):779-87. Hoffmann WH, Blanke CH, Maier JM, Luder CG, Schulz-Key H, Soboslay PT. abstract Antigenicity and specificity of very low molecular weight Onchocerca volvulus polypeptides in the range 2.2-12.5 kD. Trop Med Int Health. 1997 Jul;2(7):635-45. Baize S, Wahl G, Soboslay PT, Egwang TG, Georges AJ. abstract T helper responsiveness in human Loa loa infection; defective specific proliferation and cytokine production by CD4+ T cells from microfilaraemic subjects compared with amicrofilaraemics. Clin Exp Immunol. 1997 May;108(2):272-8. Soboslay PT, Geiger SM, Weiss N, Banla M, Luder CG, Dreweck CM, Batchassi E, Boatin BA, Stadler A, Schulz-Key H. abstract The diverse expression of immunity in humans at distinct states of Onchocerca volvulus infection. Immunology. 1997 Apr;90(4):592-9.

Geiger SM, Hoffmann W, Rapp J, Schulz-Key H, Eisenbeiss WF. Filariidae: cross-protection in filarial infections. Exp Parasitol. 1996 Aug;83(3):352-6. No abstract available. Luder CG, Schulz-Key H, Banla M, Pritze S, Soboslay PT. abstract Immunoregulation in onchocerciasis: predominance of Th1-type responsiveness to low molecular weight antigens of Onchocerca volvulus in exposed individuals without microfilaridermia and clinical disease. Clin Exp Immunol. 1996 Aug;105(2):245-53.

Soboslay PT, Luder CG, Hoffmann WH, Michaelis I, Helling G, Heuschkel C, Dreweck CM, Blanke CH, Pritze S, Banla M, et al. abstract Ivermectin-facilitated immunity in onchocerciasis; activation of parasite-specific Th1-type responses with subclinical Onchocerca volvulus infection. Clin Exp Immunol. 1994 May;96(2):238-44.

Munk ME, Soboslay PT, Arnoldi J, Brattig N, Schulz-Key H, Kaufmann SH. abstract Onchocerca volvulus provides ligands for the stimulation of human gamma/delta T lymphocytes expressing V delta 1 chains. J Infect Dis. 1993 Nov;168(5):1241-7. Luder CG, Soboslay PT, Prince AM, Greene BM, Lucius R, Schulz-Key H. abstract Experimental onchocerciasis in chimpanzees: cellular responses and antigen recognition after immunization and challenge with Onchocerca volvulus infective third-stage larvae. Parasitology. 1993 Jul;107 ( Pt 1):87-97. Seeber F, Brattig N, Soboslay PT, Pogonka T, Lorz A, Strote G, Beck E, Titanji VP, Lucius R. abstract Characterization of a recombinant T cell and B cell reactive polypeptide of Onchocerca volvulus. J Immunol. 1993 Apr 1;150(7):2931-44. Schulz-Key H, Albrecht W, Heuschkel C, Soboslay PT, Banla M, Gorgen H. abstract Efficacy of ivermectin in the treatment of concomitant Mansonella perstans infections in onchocerciasis patients. Trans R Soc Trop Med Hyg. 1993 Mar-Apr;87(2):227-9.

Soboslay PT, Dreweck CM, Hoffmann WH, Luder CG, Heuschkel C, Gorgen H, Banla M, Schulz-Key H. abstract Ivermectin-facilitated immunity in onchocerciasis. Reversal of lymphocytopenia, cellular anergy and deficient cytokine production after single treatment. Clin Exp Immunol. 1992 Sep;89(3):407-13. Lucius R, Kern A, Seeber F, Pogonka T, Willenbucher J, Taylor HR, Pinder M, Ghalib HW, Schulz-Key H, Soboslay P. abstract Specific and sensitive IgG4 immunodiagnosis of onchocerciasis with a recombinant 33 kD Onchocerca volvulus protein (Ov33). Trop Med Parasitol. 1992 Sep;43(3):139-45. Soboslay PT, Weiss N, Dreweck CM, Taylor HR, Brotman B, Schulz-Key H, Greene BM. abstract Experimental onchocerciasis in chimpanzees. Antibody response and antigen recognition after primary infection with Onchocerca volvulus. Exp Parasitol. 1992 Jun;74(4):367-80. Schulz-Key H, Soboslay PT, Hoffmann WH. Ivermectin-facilitated immunity. Parasitol Today. 1992 May;8(5):152-3. No abstract available.

Soboslay PT, Dreweck CM, Taylor HR, Brotman B, Wenk P, Greene BM.N abstract Experimental onchocerciasis in chimpanzees. Cell-mediated immune responses, and production and effects of IL-1 and IL-2 with Onchocerca volvulus infection. J Immunol. 1991 Jul 1;147(1):346-53. Awissi D, Heuschkel C, Banla M, Schulz-Key H. abstract Ivermectin in the treatment of onchocerciasis: feasibility, compliance and efficacy of a mass treatment. Bull Soc Pathol Exot. 1991;84(5 Pt 5):739-49. French.

Awadzi K, Schulz-Key H, Edwards G, Breckenridge A, Orme M, Gilles H. abstract The chemotherapy of onchocerciasis. XIV. Studies with mebendazole citrate. Trop Med Parasitol. 1990 Dec;41(4):383-6. Dohnal J, Blinn J, Wahl G, Schulz-Key H. abstract Distribution of microfilariae of Onchocerca lienalis and Onchocerca gutturosa in the skin of cattle in Germany and their development in Simulium ornatum and Culicoides nubeculosus following artificial infestation. Vet Parasitol. 1990 Jul;36(3-4):325-32. Jurgens S, Schulz-Key H. abstract Effect of ivermectin on the vertical distribution of Onchocerca volvulus microfilariae in the skin. Trop Med Parasitol. 1990 Jun;41(2):165-8. Schulz-Key H. abstract Observations on the reproductive biology of Onchocerca volvulus. Acta Leiden. 1990;59(1-2):27-44.

Taylor HR, Trpis M, Cupp EW, Brotman B, Newland HS, Soboslay PT, Greene BM. abstract Ivermectin prophylaxis against experimental Onchocerca volvulus infection in chimpanzees. Am J Trop Med Hyg. 1988 Jul;39(1):86-90. Unnasch TR, Gallin MY, Soboslay PT, Erttmann KD, Greene BM. abstract Isolation and characterization of expression cDNA clones encoding antigens of Onchocerca volvulus infective larvae. J Clin Invest. 1988 Jul;82(1):262-9. Soboslay PT, Newland HS, White AT, Erttmann KD, Albiez EJ, Taylor HR, Williams PN, Greene BM. abstract Ivermectin effect on microfilariae of Onchocerca volvulus after a single oral dose in humans. Trop Med Parasitol. 1987 Mar;38(1):8-10.

Impressum / Letzte Änderung 10/08