The University Hospital

Prof. Dr. med. Michael Koeppen EDIC

Prof. Dr. med. Michael Koeppen EDIC

Managing Senior Physician

Specialist in anesthesiology
Special intensive care medicine
Specialized rescue service

Contact

Phone number: +49 7071 29-86724

Fax number: +49 7071 29-5529

E-mail address: michael.koeppen@med.uni-tuebingen.de

Clinic / Institute / Center

  • Myocardial ischemia/reperfusion - Perioperative myocardial damage.

    Our research focuses on the study of molecular mechanisms leading to cellular adaptation to oxygen deprivation (hypoxia). In doing so, we draw on a broad methodological approach ranging from in vitro experiments to translational studies.
    In our clinical trials, we are intensively engaged in identifying predictors that increase the risk of perioperative myocardial damage. Our goal is to make anesthesia safer in the future. We are convinced that our research results can make a significant contribution to improving medical practice.
  • Acute Respiratory Distress syndrome:
    - Markers of outcome prediction in severe ARDS.
    - vvECMO
  • Mai 2023
    European Diploma in Intensive Care Medicine
  • Januar 2023
    Certificate OR Management (Professional Association of German Anesthesiologists e. V.)
  • seit 2022
    Senior physician - Central OR of the UKT
  • 2020
    Habilitation
  • 2017 - 2022
    Senior Physician - Intensive Care Medicine, University Hospital Tübingen, Clinic for Anesthesiology
  • 2016 - 2017
    Senior Physician - Interdisciplinary Neurosurgical Intensive Care Unit, LMU Hospital, Department of Anaesthesiology
  • 2012 - 2016
    Resident, LMU Hospital, Clinic for Anaesthesiology - Grosshadern Campus
  • 2012
    Assistant Professor, University of Colorado, Department of Anesthesiology, USA
  • 2010 - 2012
    Instructor, University of Colorado, Department of Anesthesiology, USA
  • 2009 - 2010
    Post-doctoral research fellow, University of Colorado, Department of Anesthesiology, USA
  • 2006 - 2009
    Resident, LMU Hospital, Clinic for Anaesthesiology - Downtown Campus
  • 2006
    Doctorate at the Physiological Institute of the University of Lübeck
  • 1999-2006
    Study of human medicine at Ludwig-Maximilians-University (LMU) Munich; PJ-scholarship at Harvard Medical School, Boston, USA
  • Methylene blue dosing strategies in critically ill adults with shock-A retrospective cohort study. Sari-Yavuz S, Heck-Swain KL, Keller M, Magunia H, Feng YS, Haeberle HA, Wied P, Schlensak C, Rosenberger P, Koeppen M. Front Med (Lausanne). 2022 Oct 28;9:1014276. doi: 10.3389/fmed.2022.1014276
  • Membrane oxygenator longevity was higher in Argatroban treated patients undergoing vvECMO. Menninger L, Körner A, Mirakaj V, Heck-Swain KL, Haeberle HA, Althaus K, Baumgartner M, Jost W, Schlensak C, Rosenberger P, Koeppen M. Eur J Clin Invest. 2023 Jan 31:e13963. doi: 10.1111/eci.13963. epub ahead of print. PMID: 36718989.Format:
  • Immune response to SARS-CoV-2 variants of concern in vaccinated individuals. Becker M, Dulovic A, Junker D, Ruetalo N, Kaiser PD, Pinilla YT, Heinzel C, Haering J, Traenkle B, Wagner TR, Layer M, Mehrlaender M, Mirakaj V, Held J, Planatscher H, Schenke-Layland K, Krause G, Strengert M, Bakchoul T, Althaus K, Fendel R, Kreidenweiss A, Koeppen M, Rothbauer U, Schindler M, Schneiderhan-Marra N. Nat Commun. 2021 May 25;12(1):3109. doi: 10.1038/s41467-021-23473-6
  • COVID-19 Related Cardiovascular Comorbidities and Complications in Critically Ill Patients: A Systematic Review and Meta-analysis. Koeppen M, Rosenberger P, Magunia H. Clin Med Insights Circ Respir Pulm Med. 2021 Feb 1;15:1179548421992327. doi: 10.1177/1179548421992327
  • Hypoxia-inducible factor 2-alpha-dependent induction of amphiregulin dampens myocardial ischemia-reperfusion injury. Koeppen M, Lee JW, Seo SW, Brodsky KS, Kreth S, Yang IV, Buttrick PM, Eckle T, Eltzschig HK. Nat Commun. 2018 Feb 26;9(1):816. doi: 10.1038/s41467-018-03105-2.
  • Red blood cell-derived semaphorin 7A promotes thrombo-inflammation in myocardial ischemia-reperfusion injury through platelet GPIb. Köhler D, Granja T, Volz J, Koeppen M, Langer HF, Hansmann G, Legchenko E, Geisler T, Bakchoul T, Eggstein C, Häberle HA, Nieswandt B, Rosenberger P. Nat Commun. 2020 Mar 11;11(1):1315.
  • Transcription-independent Induction of ERBB1 through Hypoxia-inducible Factor 2A Provides Cardioprotection during Ischemia and Reperfusion. Lee JW, Koeppen M, Seo SW, Bowser JL, Yuan X, Li J, Sibilia M, Ambardekar AV, Zhang X, Eckle T, Yoo SH, Eltzschig HK. Anesthesiology. 2020 Apr;132(4):763-780.
  • Adora2b signaling on bone marrow derived cells dampens myocardial ischemia-reperfusion injury. Koeppen M, Harter PN, Bonney S, Bonney M, Reithel S, Zachskorn C, Mittelbronn M, Eckle T. Anesthesiology. 2012 Jun;116(6):1245-57.
  • Detrimental role of the airway mucin Muc5ac during ventilator-induced lung injury. Koeppen M, McNamee EN, Brodsky KS, Aherne CM, Faigle M, Downey GP, Colgan SP, Evans CM, Schwartz DA, Eltzschig HK. Mucosal Immunol. 2013 Jul;6(4):762-75.
  • Oxygenation targets in acutely ill patients: still a matter of debate. Koeppen M, Mirakaj V. The Lancet. 2018 Dec 8;392(10163):2437.
  • Needle-free connectors catheter-related bloodstream infections: a prospective randomized controlled trial. Koeppen M, Weinert F, Oehlschlaeger S, Koerner A, Rosenberger P, Haeberle HA. Intensive Care Med Exp. 2019 Dec 2;7(1):63.
  • Early Driving Pressure Changes Predict Outcomes during Venovenous Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome. Magunia H, Haeberle HA, Henn P, Mehrländer M, Vlatten PO, Mirakaj V, Rosenberger P, Koeppen M. Crit Care Res Pract. 2020 Mar 7;2020:6958152.
  • full PubMed
  • Scopus profile
  • ORCID
  • Curriculum Pneumology
  • Main lecture anesthesiology - "When the air gets tight - breathing and airway management".
  • iKliC seminar "Beamtung