The University Hospital

Jessica Rühle

Jessica Rühle

Naturwissenschaftliche Doktorandin

Labor für Neonatale Immunologie

Contact

Phone number: +49 7071 29-86268

Fax number: +49 7071 29-4947

E-mail address: jessica.ruehle@med.uni-tuebingen.de

Clinic / Institute / Center

  • Promotionsstipendium der Jürgen Manchot Stiftung (2021-2024)
  • Posterpreis bei der 49. Jahrestagung der Gesellschaft für Neonatologie und Pädiatrische Intensivmedizin 2023 (GNPI)
  • Dietz-Ziegler S, Kewitz S, Kaiser G, Rühle J, Marmé A, Dalpke A, Cheaib B, Pauluschke-Fröhlich J, Henes M, Velic A, Pich A, Vollert A, Schaller M, Knab F, Lajqi T, Poets CF, Gille C, Köstlin-Gille N. Extracellular Vesicles Derived From the Feces of Pregnant Women Modulate T Cells Toward a Pregnancy-Supportive Phenotype In Vitro. Eur J Immunol. 2025 Sep;55(9):e70056. doi: 10.1002/eji.70056. PMID: 40970824; PMCID: PMC12447864.
  • Rühle J, Schwarz J, Dietz S, Rückle X, Schoppmeier U, Lajqi T, Poets CF, Gille C, Köstlin-Gille N. Impact of perinatal administration of probiotics on immune cell composition in neonatal mice. Pediatr Res. 2024 Dec;96(7):1645-1654. doi: 10.1038/s41390-024-03029-2. Epub 2024 Jan 26. PMID: 38278847; PMCID: PMC11772233.
  • Dietz S, Hebel J, Rühle J, Huff A, Eltzschig HK, Lajqi T, Poets CF, Gille C, Köstlin-Gille N. Impact of the adenosine receptor A2BR expressed on myeloid cells on immune regulation during pregnancy. Eur J Immunol. 2024 Dec;54(12):e2451149. doi: 10.1002/eji.202451149. Epub 2024 Oct 25. PMID: 39460389; PMCID: PMC11628929.
  • Rühle J, Ginzel M, Dietz S, Schwarz J, Lajqi T, Beer-Hammer S, Poets CF, Gille C, Köstlin-Gille N. Depletion of Ly6G-Expressing Neutrophilic Cells Leads to Altered Peripheral T-Cell Homeostasis and Thymic Development in Neonatal Mice. International Journal of Molecular Sciences. (2023); 24(9):7763. https://doi.org/10.3390/ijms24097763
  • Schwarz, J., Rühle, J., Stephan, K., Dietz, S., Geißert, J., Schoppmeier, U., Frick, J. S., Hudalla, H., Lajqi, T., Poets, C. F., Gille, C., & Köstlin-Gille, N. (2023). Targeted deletion of HIF-1α in myeloid cells of neonatal mice: decreased accumulation of myeloid-derived suppressor cells and altered microbiome. European journal of immunology, e2250144. Advance online publication. https://doi.org/10.1002/eji.202250144
  • Lajqi, T.; Köstlin-Gille, N.;Bauer, R.; Zarogiannis, S.G.; Lajqi, E.;Ajeti, V.; Dietz, S.; Kranig, S.A.; Rühle,J.; Demaj, A.; et al. Training vs.Tolerance: The Yin/Yang of theInnate Immune System. Biomedicines (2023), 11, 766. https://doi.org/10.3390/biomedicines11030766
  • Rückle, X., Rühle, J., Judd, L., Hebel, J., Dietz, S., Poets, C. F., Gille, C., & Köstlin-Gille, N. (2022). Different probiotic strains alter human cord blood monocyte responses. Pediatric research, 10.1038/s41390-022-02400-5 https://doi.org/10.1038/s41390-022-02400-5
  • Lajqi T, Köstlin-Gille N, Hillmer S, Braun M, Kranig SA, Dietz S, Krause C, Rühle J, Frommhold D, Pöschl J, Gille C, Hudalla H. Gut Microbiota-Derived Small Extracellular Vesicles Endorse Memory-like Inflammatory Responses in Murine Neutrophils. Biomedicines. (2022); 10(2):442. https://doi.org/10.3390/biomedicines10020442
  • Dietz, S., Schwarz, J., Rühle, J., Schaller, M., Fehrenbacher, B., Marmé, A., Schmid, E., Peter, A., Poets, C. F., Gille, C., & Köstlin-Gille, N. (2021). Extracellular vesicles released by myeloid-derived suppressor cells from pregnant women modulate adaptive immune responses. Cell Immunol, 361, 104276. https://doi.org/10.1016/j.cellimm.2020.104276
  • Deutsche Gesellschaft für Pneumologie und Beatmungsmedizin (DGP)
  • Deutsche Gesellschaft für Immunologie (DGfI)