Cancer research made in Tuebingen
iFIT Cluster of Excellence

312

Address: Geschäftsstelle
Röntgenweg 11
72076 Tübingen

frontend.sr-only_#{element.icon}: +49 (0)7071-29 83625

frontend.sr-only_#{element.icon}: ifitoffice@med.uni-tuebingen.de

Publications

Here you will find all relevant publications that are directly related to the iFIT Cluster of Excellence sorted by year.

2019

Zelba, H. et al. PD-1 and LAG-3 Dominate Checkpoint Receptor-Mediated T-cell Inhibition in Renal Cell Carcinoma. Cancer Immunol Res 7, 1891-1899 (2019). https://doi.org:10.1158/2326-6066.CIR-19-0146
Weiss, J. et al. Assessment of Hepatic Perfusion Using GRASP MRI: Bringing Liver MRI on a New Level. Invest Radiol 54, 737-743 (2019). https://doi.org:10.1097/RLI.0000000000000586
Schmied, B. J. et al. An Fc-Optimized CD133 Antibody for Induction of Natural Killer Cell Reactivity against Colorectal Cancer. Cancers (Basel) 11 (2019). https://doi.org:10.3390/cancers11060789
Schmied, B. J. et al. Induction of NK Cell Reactivity against B-Cell Acute Lymphoblastic Leukemia by an Fc-Optimized FLT3 Antibody. Cancers (Basel) 11 (2019). https://doi.org:10.3390/cancers11121966
Roerden, M. et al. The role of autologous stem cell transplantation in peripheral T cell lymphoma: a long-term follow-up single-center experience. J Cancer Res Clin Oncol 145, 2595-2604 (2019). https://doi.org:10.1007/s00432-019-02999-9
Rammensee, H. G. et al. A new synthetic toll-like receptor 1/2 ligand is an efficient adjuvant for peptide vaccination in a human volunteer. J Immunother Cancer 7, 307 (2019). https://doi.org:10.1186/s40425-019-0796-5
Paczulla, A. M. et al. Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasion. Nature 572, 254-259 (2019). https://doi.org:10.1038/s41586-019-1410-1
Paczulla, A. M. et al. Publisher Correction: Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasion. Nature 572, E19 (2019). https://doi.org:10.1038/s41586-019-1475-x
Moya, I. M. et al. Peritumoral activation of the Hippo pathway effectors YAP and TAZ suppresses liver cancer in mice. Science 366, 1029-1034 (2019). https://doi.org:10.1126/science.aaw9886
Mannheim, J. G. et al. Reproducibility and Comparability of Preclinical PET Imaging Data: A Multicenter Small-Animal PET Study. J Nucl Med 60, 1483-1491 (2019). https://doi.org:10.2967/jnumed.118.221994
Lorscheid, S. et al. Keratinocyte-derived IkappaBzeta drives psoriasis and associated systemic inflammation. JCI Insight 4 (2019). https://doi.org:10.1172/jci.insight.130835
Loffler, M. W. et al. A Non-interventional Clinical Trial Assessing Immune Responses After Radiofrequency Ablation of Liver Metastases From Colorectal Cancer. Front Immunol 10, 2526 (2019). https://doi.org:10.3389/fimmu.2019.02526
Kauer, J. et al. CD105 (Endoglin) as negative prognostic factor in AML. Sci Rep 9, 18337 (2019). https://doi.org:10.1038/s41598-019-54767-x
Kandabarau, S. et al. Hypertonicity-Affected Genes Are Differentially Expressed in Clear Cell Renal Cell Carcinoma and Correlate with Cancer-Specific Survival. Cancers (Basel) 12 (2019). https://doi.org:10.3390/cancers12010006
Jiang, X. et al. Shared heritability and functional enrichment across six solid cancers. Nat Commun 10, 431 (2019). https://doi.org:10.1038/s41467-018-08054-4
Jiang, X. et al. Publisher Correction: Shared heritability and functional enrichment across six solid cancers. Nat Commun 10, 4386 (2019). https://doi.org:10.1038/s41467-019-12095-8
Hoffmann, S. H. L. et al. Visualization and quantification of in vivo homing kinetics of myeloid-derived suppressor cells in primary and metastatic cancer. Theranostics 9, 5869-5885 (2019). https://doi.org:10.7150/thno.33275
Hilf, N. et al. Actively personalized vaccination trial for newly diagnosed glioblastoma. Nature 565, 240-245 (2019). https://doi.org:10.1038/s41586-018-0810-y
Hilf, N. et al. Publisher Correction: Actively personalized vaccination trial for newly diagnosed glioblastoma. Nature 566, E13 (2019). https://doi.org:10.1038/s41586-019-0959-z
Fiz, F. et al. Automated Definition of Skeletal Disease Burden in Metastatic Prostate Carcinoma: A 3D Analysis of SPECT/CT Images. Cancers (Basel) 11 (2019). https://doi.org:10.3390/cancers11060869
Figlioli, G. et al. The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer. NPJ Breast Cancer 5, 38 (2019). https://doi.org:10.1038/s41523-019-0127-5
El Maadidi, S. et al. Putative link between Polo-like kinases (PLKs) and Toll-like receptor (TLR) signaling in transformed and primary human immune cells. Sci Rep 9, 13168 (2019). https://doi.org:10.1038/s41598-019-49017-z
Dork, T. et al. Two truncating variants in FANCC and breast cancer risk. Sci Rep 9, 12524 (2019). https://doi.org:10.1038/s41598-019-48804-y
Dimitrov, S. et al. Galpha(s)-coupled receptor signaling and sleep regulate integrin activation of human antigen-specific T cells. J Exp Med 216, 517-526 (2019). https://doi.org:10.1084/jem.20181169
Brauch, H., Schroth, W., Murdter, T. & Schwab, M. Tamoxifen Pharmacogenetics and Metabolism: The Same Is Not the Same. J Clin Oncol 37, 1981-1982 (2019). https://doi.org:10.1200/JCO.19.00507
Bowden, G. D., Pichler, B. J. & Maurer, A. A Design of Experiments (DoE) Approach Accelerates the Optimization of Copper-Mediated (18)F-Fluorination Reactions of Arylstannanes. Sci Rep 9, 11370 (2019). https://doi.org:10.1038/s41598-019-47846-6
Bilich, T. et al. The HLA ligandome landscape of chronic myeloid leukemia delineates novel T-cell epitopes for immunotherapy. Blood 133, 550-565 (2019). https://doi.org:10.1182/blood-2018-07-866830
Bichmann, L. et al. MHCquant: Automated and Reproducible Data Analysis for Immunopeptidomics. J Proteome Res 18, 3876-3884 (2019). https://doi.org:10.1021/acs.jproteome.9b00313
Belnoue, E. et al. Targeting self and neo-epitopes with a modular self-adjuvanting cancer vaccine. JCI Insight 5 (2019). https://doi.org:10.1172/jci.insight.127305

2020

Zhang, H. et al. Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses. Nat Genet 52, 572-581 (2020). https://doi.org:10.1038/s41588-020-0609-2
Zbinden, A. et al. Fluorescence lifetime metabolic mapping of hypoxia-induced damage in pancreatic pseudo-islets. J Biophotonics 13, e202000375 (2020). https://doi.org:10.1002/jbio.202000375
Xiao, Q. et al. Germline variant burden in multidrug resistance transporters is a therapy-specific predictor of survival in breast cancer patients. Int J Cancer 146, 2475-2487 (2020). https://doi.org:10.1002/ijc.32898
Wormann, B. et al. Dihydropyrimidine Dehydrogenase Testing prior to Treatment with 5-Fluorouracil, Capecitabine, and Tegafur: A Consensus Paper. Oncol Res Treat 43, 628-636 (2020). https://doi.org:10.1159/000510258
Wolter, K. & Zender, L. Therapy-induced senescence - an induced synthetic lethality in liver cancer? Nat Rev Gastroenterol Hepatol 17, 135-136 (2020). https://doi.org:10.1038/s41575-020-0262-3
Wojtyniak, J. G., Britz, H., Selzer, D., Schwab, M. & Lehr, T. Data Digitizing: Accurate and Precise Data Extraction for Quantitative Systems Pharmacology and Physiologically-Based Pharmacokinetic Modeling. CPT Pharmacometrics Syst Pharmacol 9, 322-331 (2020). https://doi.org:10.1002/psp4.12511
Wistuba-Hamprecht, K., Gouttefangeas, C., Weide, B. & Pawelec, G. Immune Signatures and Survival of Patients With Metastatic Melanoma, Renal Cancer, and Breast Cancer. Front Immunol 11, 1152 (2020). https://doi.org:10.3389/fimmu.2020.01152
Wenzel, T. et al. Trans-Mucosal Efficacy of Non-Thermal Plasma Treatment on Cervical Cancer Tissue and Human Cervix Uteri by a Next Generation Electrosurgical Argon Plasma Device. Cancers (Basel) 12 (2020). https://doi.org:10.3390/cancers12020267
Weissinger, M. et al. Correlation of C-arm CT acquired parenchymal blood volume (PBV) with 99mTc-macroaggregated albumin (MAA) SPECT/CT for radioembolization work-up. PLoS One 15, e0244235 (2020). https://doi.org:10.1371/journal.pone.0244235
Weber, A. N. R. et al. Recent insights into the regulatory networks of NLRP3 inflammasome activation. J Cell Sci 133 (2020). https://doi.org:10.1242/jcs.248344
Wang, J. et al. HLA-DR15 Molecules Jointly Shape an Autoreactive T Cell Repertoire in Multiple Sclerosis. Cell 183, 1264-1281 e1220 (2020). https://doi.org:10.1016/j.cell.2020.09.054
Walter, A. et al. Correlated Multimodal Imaging in Life Sciences: Expanding the Biomedical Horizon. Front Phys-Lausanne 8 (2020). https://doi.org:ARTN 47
10.3389/fphy.2020.00047
Volpato, M. et al. Downregulation of 15-hydroxyprostaglandin dehydrogenase during acquired tamoxifen resistance and association with poor prognosis in ERalpha-positive breast cancer. Explor Target Antitumor Ther 1, 355-371 (2020). https://doi.org:10.37349/etat.2020.00021
Vogel, M. M. E. et al. Prognostic risk classification for biochemical relapse-free survival in patients with oligorecurrent prostate cancer after [(68)Ga]PSMA-PET-guided metastasis-directed therapy. Eur J Nucl Med Mol Imaging 47, 2328-2338 (2020). https://doi.org:10.1007/s00259-020-04760-8
Urbanczyk, M., Zbinden, A., Layland, S. L., Duffy, G. & Schenke-Layland, K. Controlled Heterotypic Pseudo-Islet Assembly of Human beta-Cells and Human Umbilical Vein Endothelial Cells Using Magnetic Levitation. Tissue Eng Part A 26, 387-399 (2020). https://doi.org:10.1089/ten.TEA.2019.0158
Urbanczyk, M., Layland, S. L. & Schenke-Layland, K. The role of extracellular matrix in biomechanics and its impact on bioengineering of cells and 3D tissues. Matrix Biol 85-86, 1-14 (2020). https://doi.org:10.1016/j.matbio.2019.11.005
Unger, M. S. et al. Direct Automated MALDI Mass Spectrometry Analysis of Cellular Transporter Function: Inhibition of OATP2B1 Uptake by 294 Drugs. Anal Chem 92, 11851-11859 (2020). https://doi.org:10.1021/acs.analchem.0c02186
Tremmel, R. et al. Copy number variation profiling in pharmacogenes using panel-based exome resequencing and correlation to human liver expression. Hum Genet 139, 137-149 (2020). https://doi.org:10.1007/s00439-019-02093-7
Teck, A. T. et al. Cancer testis antigen Cyclin A1 harbors several HLA-A*02:01-restricted T cell epitopes, which are presented and recognized in vivo. Cancer Immunol Immunother 69, 1217-1227 (2020). https://doi.org:10.1007/s00262-020-02519-6
Tandler, C. et al. Neutralization of B-Cell Activating Factor (BAFF) by Belimumab Reinforces Small Molecule Inhibitor Treatment in Chronic Lymphocytic Leukemia. Cancers (Basel) 12 (2020). https://doi.org:10.3390/cancers12102725
Stotz, S., Bleher, D., Kalbacher, H. & Maurer, A. Grassystatin-derived peptides selectively inhibit cathepsin E and have low affinity to cathepsin D. Biochem Biophys Res Commun 527, 238-241 (2020). https://doi.org:10.1016/j.bbrc.2020.04.070
Spenle, C. et al. Tenascin-C Orchestrates an Immune-Suppressive Tumor Microenvironment in Oral Squamous Cell Carcinoma. Cancer Immunol Res 8, 1122-1138 (2020). https://doi.org:10.1158/2326-6066.CIR-20-0074
Seitz, C. M. et al. GD2-targeted chimeric antigen receptor T cells prevent metastasis formation by elimination of breast cancer stem-like cells. Oncoimmunology 9, 1683345 (2020). https://doi.org:10.1080/2162402X.2019.1683345
Seith, F. et al. Is there a link between very early changes of primary and secondary lymphoid organs in (18)F-FDG-PET/MRI and treatment response to checkpoint inhibitor therapy? J Immunother Cancer 8 (2020). https://doi.org:10.1136/jitc-2020-000656
Schwenck, J. et al. Cancer immunotherapy is accompanied by distinct metabolic patterns in primary and secondary lymphoid organs observed by non-invasive in vivo(18)F-FDG-PET. Theranostics 10, 925-937 (2020). https://doi.org:10.7150/thno.35989
Schuhmacher, J. et al. Vaccination against RhoC induces long-lasting immune responses in patients with prostate cancer: results from a phase I/II clinical trial. J Immunother Cancer 8 (2020). https://doi.org:10.1136/jitc-2020-001157
Schroth, W. et al. Gene Expression Signatures of BRCAness and Tumor Inflammation Define Subgroups of Early-Stage Hormone Receptor-Positive Breast Cancer Patients. Clin Cancer Res 26, 6523-6534 (2020). https://doi.org:10.1158/1078-0432.CCR-20-1923
Schmidt-Hegemann, N. S. et al. Influence of localization of PSMA-positive oligo-metastases on efficacy of metastasis-directed external-beam radiotherapy-a multicenter retrospective study. Eur J Nucl Med Mol Imaging 47, 1852-1863 (2020). https://doi.org:10.1007/s00259-020-04708-y
Sahbai, S. et al. Influence of 99m-Tc-Nanocolloid Activity Concentration on Sentinel Lymph Node Detection in Endometrial Cancer: A Quantitative SPECT/CT Study. Diagnostics (Basel) 10 (2020). https://doi.org:10.3390/diagnostics10090700
Rudesheim, S. et al. Physiologically Based Pharmacokinetic Modeling of Metoprolol Enantiomers and alpha-Hydroxymetoprolol to Describe CYP2D6 Drug-Gene Interactions. Pharmaceutics 12 (2020). https://doi.org:10.3390/pharmaceutics12121200
Rohm, S. et al. Selective targeting of the alphaC and DFG-out pocket in p38 MAPK. Eur J Med Chem 208, 112721 (2020). https://doi.org:10.1016/j.ejmech.2020.112721
Roerden, M. et al. Outcome after autologous stem cell transplantation in primary refractory or relapsed Hodgkin lymphoma-a long-term follow-up single center experience. Ann Hematol 99, 265-276 (2020). https://doi.org:10.1007/s00277-019-03900-x
Roerden, M. et al. HLA Evolutionary Divergence as a Prognostic Marker for AML Patients Undergoing Allogeneic Stem Cell Transplantation. Cancers (Basel) 12 (2020). https://doi.org:10.3390/cancers12071835
Reustle, A. et al. Integrative -omics and HLA-ligandomics analysis to identify novel drug targets for ccRCC immunotherapy. Genome Med 12, 32 (2020). https://doi.org:10.1186/s13073-020-00731-8
Reinert, C. P. et al. Clinical and prognostic value of tumor volumetric parameters in melanoma patients undergoing (18)F-FDG-PET/CT: a comparison with serologic markers of tumor burden and inflammation. Cancer Imaging 20, 44 (2020). https://doi.org:10.1186/s40644-020-00322-1
Rammensee, H. G. et al. [Tumor vaccines-therapeutic vaccination against cancer]. Internist (Berl) 61, 690-698 (2020). https://doi.org:10.1007/s00108-020-00814-z
Rammensee, H. G. & Loffler, M. W. [Individualized immunotherapy for malignant tumors using peptide vaccines-maybe it does work after all?]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 63, 1380-1387 (2020). https://doi.org:10.1007/s00103-020-03227-3
Perl, R. M., Haring, A., Horger, M. S., Pfannenberg, C. & Gatidis, S. Paraneoplastic syndrome in undifferentiated embryonic sarcoma of the liver. EJNMMI Res 10, 11 (2020). https://doi.org:10.1186/s13550-020-0602-x
Pedreira, J. G. B. et al. Bioisosteric Replacement of Arylamide-Linked Spine Residues with N-Acylhydrazones and Selenophenes as a Design Strategy to Novel Dibenzosuberone Derivatives as Type I 1/2 p38alpha MAP Kinase Inhibitors. J Med Chem 63, 7347-7354 (2020). https://doi.org:10.1021/acs.jmedchem.0c00508
Pedersen, N. W. et al. Optimization in Detection of Antigen-Specific T Cells Through Differentially Labeled MHC Multimers. Cytometry A 97, 955-964 (2020). https://doi.org:10.1002/cyto.a.23942
Okkelman, I. A. et al. Extracellular Ca(2+)-Sensing Fluorescent Protein Biosensor Based on a Collagen-Binding Domain. ACS Appl Bio Mater 3, 5310-5321 (2020). https://doi.org:10.1021/acsabm.0c00649
Oehus, A. K. et al. Efficacy of PSMA ligand PET-based radiotherapy for recurrent prostate cancer after radical prostatectomy and salvage radiotherapy. BMC Cancer 20, 362 (2020). https://doi.org:10.1186/s12885-020-06883-5
Neveu, M. A. et al. Lactate Production Precedes Inflammatory Cell Recruitment in Arthritic Ankles: an Imaging Study. Mol Imaging Biol 22, 1324-1332 (2020). https://doi.org:10.1007/s11307-020-01510-y
Neef, S. K. et al. Optimized protocol for metabolomic and lipidomic profiling in formalin-fixed paraffin-embedded kidney tissue by LC-MS. Anal Chim Acta 1134, 125-135 (2020). https://doi.org:10.1016/j.aca.2020.08.005
Neef, S. K. et al. Metabolic Drug Response Phenotyping in Colorectal Cancer Organoids by LC-QTOF-MS. Metabolites 10 (2020). https://doi.org:10.3390/metabo10120494
Nardin, J. M. et al. The Influences of Adherence to Tamoxifen and CYP2D6 Pharmacogenetics on Plasma Concentrations of the Active Metabolite (Z)-Endoxifen in Breast Cancer. Clin Transl Sci 13, 284-292 (2020). https://doi.org:10.1111/cts.12707
Muller, A. et al. The CDK4/6-EZH2 pathway is a potential therapeutic target for psoriasis. J Clin Invest 130, 5765-5781 (2020). https://doi.org:10.1172/JCI134217
Michelotti, F. C. et al. PET/MRI enables simultaneous in vivo quantification of beta-cell mass and function. Theranostics 10, 398-410 (2020). https://doi.org:10.7150/thno.33410
Meraz-Torres, F., Ploger, S., Garbe, C., Niessner, H. & Sinnberg, T. Disulfiram as a Therapeutic Agent for Metastatic Malignant Melanoma-Old Myth or New Logos? Cancers (Basel) 12 (2020). https://doi.org:10.3390/cancers12123538
Maurer, S., Kopp, H. G., Salih, H. R. & Kropp, K. N. Modulation of Immune Responses by Platelet-Derived ADAM10. Front Immunol 11, 44 (2020). https://doi.org:10.3389/fimmu.2020.00044
Marzec, J. et al. (68)Ga-PSMA-PET/CT-directed IGRT/SBRT for oligometastases of recurrent prostate cancer after initial surgery. Acta Oncol 59, 149-156 (2020). https://doi.org:10.1080/0284186X.2019.1669816
Marklin, M. et al. CD105 (endoglin) as risk marker in AML patients undergoing stem cell transplantation. Int J Hematol 112, 57-64 (2020). https://doi.org:10.1007/s12185-020-02875-0
Marklin, M. et al. Oral intake of lipopolysaccharide regulates toll-like receptor 4-dependent granulopoiesis. Exp Biol Med (Maywood) 245, 1254-1259 (2020). https://doi.org:10.1177/1535370220931043
Lubke, M. et al. Identification of HCMV-derived T cell epitopes in seropositive individuals through viral deletion models. J Exp Med 217 (2020). https://doi.org:10.1084/jem.20191164
Liu, J. et al. Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk. Sci Rep 10, 9688 (2020). https://doi.org:10.1038/s41598-020-65665-y
Kramer, I. et al. Breast Cancer Polygenic Risk Score and Contralateral Breast Cancer Risk. Am J Hum Genet 107, 837-848 (2020). https://doi.org:10.1016/j.ajhg.2020.09.001
Kosnopfel, C. et al. Tumour Progression Stage-Dependent Secretion of YB-1 Stimulates Melanoma Cell Migration and Invasion. Cancers (Basel) 12 (2020). https://doi.org:10.3390/cancers12082328
Kaufmann, S. et al. Simultaneous whole-body PET/MRI with integrated multiparametric MRI for primary staging of high-risk prostate cancer. World J Urol 38, 2513-2521 (2020). https://doi.org:10.1007/s00345-019-03066-1
Kauer, J. et al. Tocilizumab, but not dexamethasone, prevents CRS without affecting antitumor activity of bispecific antibodies. J Immunother Cancer 8 (2020). https://doi.org:10.1136/jitc-2020-000621
Jodicke, L., Zender, L. & Malek, N. P. [Personalized treatment of cholangiocellular carcinoma (CCA)]. Internist (Berl) 61, 170-174 (2020). https://doi.org:10.1007/s00108-019-00723-w
Jensen, O. et al. Variability and Heritability of Thiamine Pharmacokinetics With Focus on OCT1 Effects on Membrane Transport and Pharmacokinetics in Humans. Clin Pharmacol Ther 107, 628-638 (2020). https://doi.org:10.1002/cpt.1666
Jaeckle, E. et al. Towards automation in biologics production via Raman micro-spectroscopy, laser-induced forward cell transfer and surface-enhanced Raman spectroscopy. J Biotechnol 323, 313-321 (2020). https://doi.org:10.1016/j.jbiotec.2020.09.001
Ilhan, H., la Fougere, C. & Krause, B. J. [PSMA-based theranostics for prostate cancer : From imaging to treatment]. Urologe A 59, 617-625 (2020). https://doi.org:10.1007/s00120-020-01193-x
Hilke, F. J. et al. Distinct Mutation Patterns Reveal Melanoma Subtypes and Influence Immunotherapy Response in Advanced Melanoma Patients. Cancers (Basel) 12 (2020). https://doi.org:10.3390/cancers12092359
Heitmann, J. S. et al. Protocol of a prospective, multicentre phase I study to evaluate the safety, tolerability and preliminary efficacy of the bispecific PSMAxCD3 antibody CC-1 in patients with castration-resistant prostate carcinoma. BMJ Open 10, e039639 (2020). https://doi.org:10.1136/bmjopen-2020-039639
Heitmann, J. S. et al. Identification of CD318 (CDCP1) as novel prognostic marker in AML. Ann Hematol 99, 477-486 (2020). https://doi.org:10.1007/s00277-020-03907-9
Heitmann, J. S. et al. Fc gamma receptor expression serves as prognostic and diagnostic factor in AML. Leuk Lymphoma 61, 2466-2474 (2020). https://doi.org:10.1080/10428194.2020.1775208
Haller, V., Nahidino, P., Forster, M. & Laufer, S. A. An updated patent review of p38 MAP kinase inhibitors (2014-2019). Expert Opin Ther Pat 30, 453-466 (2020). https://doi.org:10.1080/13543776.2020.1749263
Haen, S. P., Loffler, M. W., Rammensee, H. G. & Brossart, P. Towards new horizons: characterization, classification and implications of the tumour antigenic repertoire. Nat Rev Clin Oncol 17, 595-610 (2020). https://doi.org:10.1038/s41571-020-0387-x
Guo, S. et al. Comparability of Raman Spectroscopic Configurations: A Large Scale Cross-Laboratory Study. Anal Chem 92, 15745-15756 (2020). https://doi.org:10.1021/acs.analchem.0c02696
Grimm, J., Kiessling, F. & Pichler, B. J. Quo Vadis, Molecular Imaging? J Nucl Med 61, 1428-1434 (2020). https://doi.org:10.2967/jnumed.120.241984
Ghosh, M. et al. The Impact of Biomaterial Cell Contact on the Immunopeptidome. Front Bioeng Biotechnol 8, 571294 (2020). https://doi.org:10.3389/fbioe.2020.571294
Gehringer, M. Covalent inhibitors: back on track? Future Med Chem 12, 1363-1368 (2020). https://doi.org:10.4155/fmc-2020-0118
Forster, M. et al. Discovery of a Novel Class of Covalent Dual Inhibitors Targeting the Protein Kinases BMX and BTK. Int J Mol Sci 21 (2020). https://doi.org:10.3390/ijms21239269
Feng, H. et al. Transcriptome-wide association study of breast cancer risk by estrogen-receptor status. Genet Epidemiol 44, 442-468 (2020). https://doi.org:10.1002/gepi.22288
Fachal, L. et al. Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes. Nat Genet 52, 56-73 (2020). https://doi.org:10.1038/s41588-019-0537-1
Ewels, P. A. et al. The nf-core framework for community-curated bioinformatics pipelines. Nat Biotechnol 38, 276-278 (2020). https://doi.org:10.1038/s41587-020-0439-x
Escala-Garcia, M. et al. A network analysis to identify mediators of germline-driven differences in breast cancer prognosis. Nat Commun 11, 312 (2020). https://doi.org:10.1038/s41467-019-14100-6
Daum, R. et al. Fibronectin Adsorption on Electrospun Synthetic Vascular Grafts Attracts Endothelial Progenitor Cells and Promotes Endothelialization in Dynamic In Vitro Culture. Cells 9 (2020). https://doi.org:10.3390/cells9030778
Chenoweth, M. J. et al. Global Pharmacogenomics Within Precision Medicine: Challenges and Opportunities. Clin Pharmacol Ther 107, 57-61 (2020). https://doi.org:10.1002/cpt.1664
Chen, M. et al. Sorafenib Activity and Disposition in Liver Cancer Does Not Depend on Organic Cation Transporter 1. Clin Pharmacol Ther 107, 227-237 (2020). https://doi.org:10.1002/cpt.1588
Busche, M. et al. HepaChip-MP - a twenty-four chamber microplate for a continuously perfused liver coculture model. Lab Chip 20, 2911-2926 (2020). https://doi.org:10.1039/d0lc00357c
Bucher, P. et al. Targeting chronic NFAT activation with calcineurin inhibitors in diffuse large B-cell lymphoma. Blood 135, 121-132 (2020). https://doi.org:10.1182/blood.2019001866
Bresnahan, E., Ramadori, P., Heikenwalder, M., Zender, L. & Lujambio, A. Novel patient-derived preclinical models of liver cancer. J Hepatol 72, 239-249 (2020). https://doi.org:10.1016/j.jhep.2019.09.028
Brenner, E. et al. Cancer immune control needs senescence induction by interferon-dependent cell cycle regulator pathways in tumours. Nat Commun 11, 1335 (2020). https://doi.org:10.1038/s41467-020-14987-6
Brendle, C. et al. Determinants of activity of brown adipose tissue in lymphoma patients. Sci Rep 10, 21802 (2020). https://doi.org:10.1038/s41598-020-78419-7
Bilich, T. et al. Mass spectrometry-based identification of a B-cell maturation antigen-derived T-cell epitope for antigen-specific immunotherapy of multiple myeloma. Blood Cancer J 10, 24 (2020). https://doi.org:10.1038/s41408-020-0288-3
Berchtold, S. et al. Assessing and Overcoming Resistance Phenomena against a Genetically Modified Vaccinia Virus in Selected Cancer Cell Lines. Int J Mol Sci 21 (2020). https://doi.org:10.3390/ijms21207618
Armanious, K. et al. Independent attenuation correction of whole body [(18)F]FDG-PET using a deep learning approach with Generative Adversarial Networks. EJNMMI Res 10, 53 (2020). https://doi.org:10.1186/s13550-020-00644-y

2021

Zhou, Y. et al. Regulation of Platelet-Derived ADAM17: A Biomarker Approach for Breast Cancer? Diagnostics (Basel) 11 (2021). https://doi.org:10.3390/diagnostics11071188
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