NET Tumors
Neuroendocrine tumors
Hormone-producing (endocrine) cells found throughout the body can develop into neuroendocrine tumor cells and thus into so-called NET tumors; NET tumors are most frequently found in the gastrointestinal tract. NET tumors are rare overall, but are increasing in frequency: the annual incidence rate is currently more than 5 per 100,000 inhabitants.
Neuroendocrine neoplasms (NEN).
NEN are divided into neuroendocrine tumors(NET) and neuroendocrine carcinomas(NEC). NEN are most commonly found in the gastrointestinal tract and lungs. They are rare overall, but are increasing in frequency.
Learn moreThe therapy of NET tumors has several goals
Complete tumor removal
If a NET tumor is detected at an early stage, it may be possible to achieve a cure by completely removing the tumor; however, regular follow-up examinations must be carried out to detect any recurrence or metastases as quickly as possible.However, regular follow-up examinations must take place in order to detect any recurrence (relapse) or even previously undetected metastases as quickly as possible and also to combat them in a targeted manner.
Mitigate hormone production
If a cure is not possible, the aim is to mitigate the symptoms caused by hormone production on the part of the NET tumor cells as much as possible.
Inhibition of proliferation
In addition, inhibition of tumor cell proliferation and thus effective control of NET tumor growth must be ensured.
Personalized tumor therapy
Personalized tumor therapy
Biotherapy with somatostatin analogues
Depending on the growth rate of the tumor cell (determined by the proliferation markers Ki67 or MIB-1) and the severity of symptoms, biotherapy with so-called somatostatin analogues is primarily used to curb excessive signals for tumor cell growth.
Additional therapeutic modalities
- Surgery,
- Endoscopy,
- Tumor-destructive procedures of metastases in the liver (SIRT, TACE),
- radiotherapy (peptide receptor-based radiotherapy (PRRT)),
- targeted molecular therapies (MT) and
- chemotherapies (CTx)
Treatment at the NET Center Tübingen
At the University Hospital and the Medical Faculty of Tübingen, the excellent existing potential for an improved development of novel treatment options for NET tumors is bundled in a university center, which is assigned to the Comprehensive Cancer Center (CCC) Tübingen-Stuttgart.
Our declared goal is to arrive at innovative approaches in this way, both in NET diagnostics and, in particular, in NET therapy.
Learn moreBased on these options, an individual and thus personalized tumor therapy is put together for each NET patient.
Research for new therapeutic approaches
Research for
new therapeutic approaches
However, after a shorter or longer duration, inefficacies (resistances) to the NET therapies used may develop. This can lead to treatment failure, which then significantly threatens and limits quality and length of life.
Accordingly, there is a great need for research to develop ever better and equally well-tolerated therapeutic approaches, especially for such situations.
Research at the NET Center
The focus of the center is the interdisciplinary cooperation of all institutions at the hospital and the medical faculty in basic research and translational therapy development.
Learn moreCertificates and Associations
Focus: Top Nationales Krankenhaus 2024
Kooperation für Transparenz und Qualität im Gesundheitswesen
Qualitätspartnerschaft mit der PKV
Erfolgsfaktor Familie
Die Altersvorsorge für den Öffentlichen Dienst