Mechanisms that contribute to metabolic diseases

Obesity and metabolic diseases, such as diabetes, pose significant health burdens in both modern and developing societies. The development of obesity is influenced by various factors that disrupt the regulation of energy balance in the human body. While nutrient absorption is a crucial aspect of energy balance, our understanding of how we regulate the absorption of nutrients we consume remains limited. The group led by Prof. Dr. Reiner Jumpertz-von Schwartzenberg investigates the underlying mechanisms that contribute to metabolic diseases, with a specific focus on the interplay between the gut microbiome and host metabolism. Their research is centered around understanding the intricate processes involved in nutrient absorption and how the gut microbiota influences these processes, aiming to shed light on the development of metabolic diseases. By exploring the intersection of nutrient absorption, gut microbiota, and host metabolism, this group strives to uncover new insights into the prevention, treatment and remission of obesity and related metabolic disorders such as prediabetes and overt type 2 diabetes.

Prof. Dr. Reiner Jumpertz-von Schwartzenberg has been appointed as Full Professor for Clinical Metabolism and Obesity Research at the Medical Faculty of the University of Tübingen in conjunction with the Helmholtz Center Munich since May 2022. He studied medicine in Bochum and Leipzig where he obtained his doctorate in 2012. Between 2011 and 2021 he has completed his clinical training at the Charité in Berlin and became a board-certified internist, endocrinologist and diabetologist. He became member of the first clinician scientist program in Germany focussing on the interaction of diets, metabolism and the gut microbiome.  During his stays abroad as a visiting scientist at the National Institute of Health (NIH) in the USA and the University of California/San Francisco, Prof. Dr. Reiner Jumpertz-von Schwartzenberg gained a deep understanding in clinical trial design in human metabolism research and basic translational microbiome science. Since 2021, Prof. Dr. Jumpertz-von Schwartzenberg serves as a senior physician for the Department of Diabetology, Endocrinology, and Nephrology, and is the head of the clinical study center at the Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University Hospital Tübingen. Additionally, he leads a Helmholtz Young Investigator Group and is a Junior Research Group leader in the Cluster of Excellence Controlling Microbes to Fight Infections (CMFI) in Tübingen. His research focuses on understanding the mechanisms underlying the development, treatment and remission of metabolic diseases, with a specific emphasis on exploring the interactions between the gut microbiome and host metabolism.

Interview

Mechanisms that contribute to metabolic diseases – Prof. Dr. Jumpertz-von Schwartzenberg

Join Prof. Dr. Reiner Jumpertz-von Schwartzenberg as he explains how nutrient absorption and gut microbes are connected—and how this relationship may hold the key to treating obesity and metabolic disease. Discover how cutting-edge research is helping to unravel the hidden pathways of energy balance.

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  • Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen
  • Department of Internal Medicine IV, Division of Diabetology, Endocrinology and Nephrology, Eberhard-Karls University Tübingen
  • German Center for Diabetes Research (DZD)
  • Cluster of Excellence EXC 2124 “Controlling Microbes to Fight Infections” (CMFI), University of Tübingen
metabolic
diseases
interplay
between gut microbiome and host metabolism
nutrient
absorption

Slected publications

  • 2025

    Prediabetes remission and cardiovascular morbidity and mortality: post-hoc analyses from the Diabetes Prevention Program Outcome study and the DaQing Diabetes Prevention Outcome study

    Vazquez Arreola E, Gong Q, Hanson RL, Wang J, Sandforth L, He S, Sandforth A, Qian X, Giacca M, Bornstein SR, Fritsche A, Stefan N, Preissl H, Gregg EW, Marx N, Jumpertz-von Schwartzenberg R, Li G, Birkenfeld AL. Prediabetes remission and cardiovascular morbidity and mortality: post-hoc analyses from the Diabetes Prevention Program Outcome study and the DaQing Diabetes Prevention Outcome study.

    Lancet Diabetes Endocrinol. 2026 Feb;14(2):137-148. doi: 10.1016/S2213-8587(25)00295-5. Epub 2025 Dec 12. PMID: 41397402. https://doi.org/10.1016/s2213-8587(25)00295-5
  • 2025

    Prevention of type 2 diabetes through prediabetes remission without weight loss

    Sandforth A, Arreola EV, Hanson RL, Wewer Albrechtsen NJ, Holst JJ, Ahrends R, Coman C, Gerst F, Lorza-Gil E, Cheng Y, Sandforth L, Katzenstein S, Ganslmeier M, Seissler J, Hauner H, Perakakis N, Wagner R, Machann J, Schick F, Peter A, Lehmann R, Weigert C, Maurer J, Preissl H, Heni M, Szendrödi J, Kopf S, Solimena M, Schwarz P, Blüher M, Häring HU, Hrabé de Angelis M, Schürmann A, Kabisch S, Mai K, Pfeiffer AFH, Bornstein S, Stumvoll M, Roden M, Stefan N, Fritsche A, Birkenfeld AL, Jumpertz von Schwartzenberg R. Prevention of type 2 diabetes through prediabetes remission without weight loss.

    Nat Med. 2025 Oct;31(10):3330-3340. doi: 10.1038/s41591-025-03944-9. Epub 2025 Sep 29. PMID: 41023486; PMCID: PMC12532634. https://doi.org/10.1038/s41591-025-03944-9
  • 2025

    Superiority of 1 h plasma glucose vs fasting plasma glucose, 2 h plasma glucose and HbA1c for the diagnosis of type 2 diabetes

    Wang Y, Ram J, Bianchi C, Fiorentino TV, Kim SS, Kim J, Ryang S, Del Prato S, Sesti G, Sandforth L, Preissl H, Jumpertz von Schwartzenberg R, Stefan N, Fritsche A, Ha J, Birkenfeld AL, Bergman M. Superiority of 1 h plasma glucose vs fasting plasma glucose, 2 h plasma glucose and HbA1c for the diagnosis of type 2 diabetes.

    Diabetologia. 2025 Dec 12. doi: 10.1007/s00125-025-06632-y. Epub ahead of print. PMID: 41388091. https://doi.org/10.1007/s00125-025-06632-y
  • 2025

    Differential risk assessment in persons at risk of type 2 diabetes using urinary peptidomics

    Schork A, Fritsche A, Schleicher ED, Peter A, Heni M, Stefan N, von Schwartzenberg RJ, Guthoff M, Mischak H, Siwy J, Birkenfeld AL, Wagner R. Differential risk assessment in persons at risk of type 2 diabetes using urinary peptidomics.

    Metabolism. 2025 Jun;167:156174. doi: 10.1016/j.metabol.2025.156174. Epub 2025 Feb 27. PMID: 40023439. https://doi.org/10.1016/j.metabol.2025.156174
  • 2025

    Comparison of GFR estimation in patients with diabetes mellitus using the EKFC and CKD-EPI equations

    Eisinger F, Neumann M, Wörn M, Fritsche A, Heyne N, Peter A, Birkenfeld AL, von Schwartzenberg RJ, Artunc F. Comparison of GFR estimation in patients with diabetes mellitus using the EKFC and CKD-EPI equations.

    J Nephrol. 2025 Mar;38(2):707-716. doi: 10.1007/s40620-024-02202-4. Epub 2025 Jan 10. PMID: 39792299; PMCID: PMC11961541. https://doi.org/10.1007/s40620-024-02202-4
  • 2025

    Subphenotype-Dependent Benefits of Bariatric Surgery for Individuals at Risk for Type 2 Diabetes

    Sandforth L, Raverdy V, Sandforth A, Bauvin P, Chatelain E, Verkindt H, Mingrone G, Guidone C, Verrastro O, Zhou K, Archid R, Mihaljevic A, Caiazzo R, Baud G, Marciniak C, Chetboun M, Ganslmeier M, Minelli Faiao V, Heni M, Fritsche L, Moller A, Kantartzis K, Peter A, Lehmann R, Wagner R, Prystupa K, Fritsche A, Stefan N, Preissl H, Birkenfeld AL, Jumpertz von Schwartzenberg R, Pattou F. Subphenotype-Dependent Benefits of Bariatric Surgery for Individuals at Risk for Type 2 Diabetes.

    Diabetes Care. 2025 Jun 1;48(6):996-1006. doi: 10.2337/dc25-0160. PMID: 40214701; PMCID: PMC12094208. https://doi.org/10.2337/dc25-0160
  • 2025

    Proteomic and Metabolomic Signatures in Prediabetes Progressing to Diabetes or Reversing to Normoglycemia Within 1 Year

    Barovic M, Hahn JJ, Heinrich A, Adhikari T, Schwarz P, Mirtschink P, Funk A, Kabisch S, Pfeiffer AFH, Blüher M, Seissler J, Stefan N, Wagner R, Fritsche A, Jumpertz von Schwartzenberg R, Chlamydas S, Harb H, Mantzoros CS, Chavakis T, Schürmann A, Birkenfeld AL, Roden M, Solimena M, Bornstein SR, Perakakis N. Proteomic and Metabolomic Signatures in Prediabetes Progressing to Diabetes or Reversing to Normoglycemia Within 1 Year.

    Diabetes Care. 2025 Mar 1;48(3):405-415. doi: 10.2337/dc24-1412. PMID: 39746149. https://doi.org/10.2337/dc24-1412
  • 2024

    Endoscopic ultrasound-guided ethanol ablation versus surgical resection of insulinomas

    Jürgensen C, Eckart M, Haberbosch L, Tacke F, Sandforth A, Birkenfeld AL, Overkamp D, Daniels M, Mogl M, Goretzki P, Strasburger C, Mai K, Spranger J, Jumpertz von Schwartzenberg R. Endoscopic ultrasound-guided ethanol ablation versus surgical resection of insulinomas.

    Ultraschall Med. 2024 Oct;45(5):519-527. English. doi: 10.1055/a-2204-5814. Epub 2023 Nov 6. PMID: 37931914. https://doi.org/10.1055/a-2204-5814
  • 2024

    Oxytocin does not acutely improve glucose tolerance in men with type 2 diabetes

    Goll N, Moszka N, Kantartzis K, Preissl H, Gruber T, Fritsche L, Jumpertz-von Schwarzenberg R, García-Cáceres C, Fritsche A, Hallschmid M. Oxytocin does not acutely improve glucose tolerance in men with type 2 diabetes.

    Diabetes Obes Metab. 2024 Oct;26(10):4562-4570. doi: 10.1111/dom.15812. Epub 2024 Aug 8. PMID: 39118203. https://doi.org/10.1111/dom.15812
  • 2024

    Carrageenan and insulin resistance in humans: a randomised double-blind cross-over trial

    Wagner R, Buettner J, Heni M, Fritsche L, Kullmann S, Wagmüller M, Peter A, Preissl H, Machann J, Jumpertz von Schwartzenberg R, Birkenfeld AL, Pape UF, van Hall G, Plomgaard P, Häring HU, Fritsche A, Thompson KN, Klein R, Stefan N. Carrageenan and insulin resistance in humans: a randomised double-blind cross-over trial.

    BMC Med. 2024 Nov 26;22(1):558. doi: 10.1186/s12916-024-03771-8. PMID: 39593091; PMCID: PMC11590543. https://doi.org/10.1186/s12916-024-03771-8
  • 2024

    Role of weight loss-induced prediabetes remission in the prevention of type 2 diabetes: time to improve diabetes prevention

    Jumpertz von Schwartzenberg R, Vazquez Arreola E, Sandforth A, Hanson RL, Birkenfeld AL. Role of weight loss-induced prediabetes remission in the prevention of type 2 diabetes: time to improve diabetes prevention.

    Diabetologia. 2024 Aug;67(8):1714-1718. doi: 10.1007/s00125-024-06178-5. Epub 2024 May 23. PMID: 38780785; PMCID: PMC11344004. https://doi.org/10.1007/s00125-024-06178-5
  • 2023

    Atrial natriuretic peptide and leptin interactions in healthy men

    Daniels MA, Fischer-Posovszky P, Boschmann M, Jumpertz-von Schwartzenberg R, Müller TD, Sandforth L, Frank-Podlech S, Hülskämper S, Peter A, Wabitsch M, Jordan J, Birkenfeld AL. Atrial natriuretic peptide and leptin interactions in healthy men.

    Front Endocrinol (Lausanne). 2023 Jun 30;14:1195677. doi: 10.3389/fendo.2023.1195677. PMID: 37455918; PMCID: PMC10348356. https://doi.org/10.3389/fendo.2023.1195677
  • 2023

    Mechanisms of weight loss-induced remission in people with prediabetes: a post-hoc analysis of the randomised, controlled, multicentre Prediabetes Lifestyle Intervention Study (PLIS)

    Sandforth A, von Schwartzenberg RJ, Arreola EV, Hanson RL, Sancar G, Katzenstein S, Lange K, Preißl H, Dreher SI, Weigert C, Wagner R, Kantartzis K, Machann J, Schick F, Lehmann R, Peter A, Katsouli N, Ntziachristos V, Dannecker C, Fritsche L, Perakakis N, Heni M, Nawroth PP, Kopf S, Pfeiffer AFH, Kabisch S, Stumvoll M, Schwarz PEH, Hauner H, Lechner A, Seissler J, Yurchenko I, Icks A, Solimena M, Häring HU, Szendroedi J, Schürmann A, de Angelis MH, Blüher M, Roden M, Bornstein SR, Stefan N, Fritsche A, Birkenfeld AL. Mechanisms of weight loss-induced remission in people with prediabetes: a post-hoc analysis of the randomised, controlled, multicentre Prediabetes Lifestyle Intervention Study (PLIS).

    Lancet Diabetes Endocrinol. 2023 Nov;11(11):798-810. doi: 10.1016/S2213-8587(23)00235-8. Epub 2023 Sep 25. Erratum in: Lancet Diabetes Endocrinol. 2024 Jan;12(1):e1. doi: 10.1016/S2213-8587(23)00350-9. PMID: 37769677. https://doi.org/10.1016/s2213-8587(23)00235-8
  • 2022

    Spironolactone is associated with reduced mitotane levels in adrenocortical carcinoma patients

    Haberbosch L, Maurer L, Sandforth A, Wernicke C, Spranger J, Mai K, Jumpertz von Schwartzenberg R. Spironolactone is associated with reduced mitotane levels in adrenocortical carcinoma patients.

    Endocr Relat Cancer. 2022 Feb 3;29(3):121-128. doi: 10.1530/ERC-21-0202. PMID: 35014973. https://doi.org/10.1530/erc-21-0202
  • 2022

    Effects of caloric restriction on the gut microbiome are linked with immune senescence

    Sbierski-Kind J, Grenkowitz S, Schlickeiser S, Sandforth A, Friedrich M, Kunkel D, Glauben R, Brachs S, Mai K, Thürmer A, Radonić A, Drechsel O, Turnbaugh PJ, Bisanz JE, Volk HD, Spranger J, von Schwartzenberg RJ. Effects of caloric restriction on the gut microbiome are linked with immune senescence.

    Microbiome. 2022 Apr 4;10(1):57. doi: 10.1186/s40168-022-01249-4. PMID: 35379337; PMCID: PMC8978410. https://doi.org/10.1186/s40168-022-01249-4
  • 2021

    Long-term outcomes of bariatric surgery in patients with bi-allelic mutations in the POMC, LEPR, and MC4R genes

    Poitou C, Puder L, Dubern B, Krabusch P, Genser L, Wiegand S, Verkindt H, Köhn A, von Schwartzenberg RJ, Flück C, Pattou F, Laville M, Kühnen P, Clément K. Long-term outcomes of bariatric surgery in patients with bi-allelic mutations in the POMC, LEPR, and MC4R genes.

    Surg Obes Relat Dis. 2021 Aug;17(8):1449-1456. doi: 10.1016/j.soard.2021.04.020. Epub 2021 May 8. PMID: 34083135. https://doi.org/10.1016/j.soard.2021.04.020
  • 2021

    Caloric restriction disrupts the microbiota and colonization resistance

    von Schwartzenberg RJ, Bisanz JE, Lyalina S, Spanogiannopoulos P, Ang QY, Cai J, Dickmann S, Friedrich M, Liu SY, Collins SL, Ingebrigtsen D, Miller S, Turnbaugh JA, Patterson AD, Pollard KS, Mai K, Spranger J, Turnbaugh PJ. Caloric restriction disrupts the microbiota and colonization resistance.

    Nature. 2021 Jul;595(7866):272-277. doi: 10.1038/s41586-021-03663-4. Epub 2021 Jun 23. PMID: 34163067; PMCID: PMC8959578. https://doi.org/10.1038/s41586-021-03663-4
  • 2021

    Caloric restriction disrupts the microbiota and colonization resistance

    von Schwartzenberg RJ, Bisanz JE, Lyalina S, Spanogiannopoulos P, Ang QY, Cai J, Dickmann S, Friedrich M, Liu SY, Collins SL, Ingebrigtsen D, Miller S, Turnbaugh JA, Patterson AD, Pollard KS, Mai K, Spranger J, Turnbaugh PJ. Caloric restriction disrupts the microbiota and colonization resistance.

    Nature. 2021 Jul;595(7866):272-277. doi: 10.1038/s41586-021-03663-4. Epub 2021 Jun 23. PMID: 34163067; PMCID: PMC8959578. https://doi.org/10.1038/s41586-021-03663-4
  • 2020

    Effects of underfeeding and oral vancomycin on gut microbiome and nutrient absorption in humans

    Basolo A, Hohenadel M, Ang QY, Piaggi P, Heinitz S, Walter M, Walter P, Parrington S, Trinidad DD, von Schwartzenberg RJ, Turnbaugh PJ, Krakoff J. Effects of underfeeding and oral vancomycin on gut microbiome and nutrient absorption in humans.

    Nat Med. 2020 Apr;26(4):589-598. doi: 10.1038/s41591-020-0801-z. Epub 2020 Mar 23. PMID: 32235930. https://doi.org/10.1038/s41591-020-0801-z
  • 2020

    Association between Subcutaneous Adipose Tissue Inflammation, Insulin Resistance, and Calorie Restriction in Obese Females

    Sbierski-Kind J, Mai K, Kath J, Jurisch A, Streitz M, Kuchenbecker L, Babel N, Nienen M, Jürchott K, Spranger L, Jumpertz von Schwartzenberg R, Decker AM, Krüger U, Volk HD, Spranger J. Association between Subcutaneous Adipose Tissue Inflammation, Insulin Resistance, and Calorie Restriction in Obese Females.

    J Immunol. 2020 Jul 1;205(1):45-55. doi: 10.4049/jimmunol.2000108. Epub 2020 Jun 1. PMID: 32482712. https://doi.org/10.4049/jimmunol.2000108
  • 2020

    Effects of underfeeding and oral vancomycin on gut microbiome and nutrient absorption in humans

    Basolo A, Hohenadel M, Ang QY, Piaggi P, Heinitz S, Walter M, Walter P, Parrington S, Trinidad DD, von Schwartzenberg RJ, Turnbaugh PJ, Krakoff J. Effects of underfeeding and oral vancomycin on gut microbiome and nutrient absorption in humans.

    Nat Med. 2020 Apr;26(4):589-598. doi: 10.1038/s41591-020-0801-z. Epub 2020 Mar 23. PMID: 32235930. https://doi.org/10.1038/s41591-020-0801-z
  • 2018

    Effects of a combined dietary, exercise and behavioral intervention and sympathetic system on body weight maintenance after intended weight loss: Results of a randomized controlled trial

    Mai K, Brachs M, Leupelt V, Jumpertz-von Schwartzenberg R, Maurer L, Grüters-Kieslich A, Ernert A, Bobbert T, Krude H, Spranger J. Effects of a combined dietary, exercise and behavioral intervention and sympathetic system on body weight maintenance after intended weight loss: Results of a randomized controlled trial.

    Metabolism. 2018 Jun;83:60-67. doi: 10.1016/j.metabol.2018.01.003. Epub 2018 Jan 31. PMID: 29360493. https://doi.org/10.1016/j.metabol.2018.01.003
  • 2018

    Peripheral Endocannabinoids Associated With Energy Expenditure in Native Americans of Southwestern Heritage

    Heinitz S, Basolo A, Piaggi P, Piomelli D, Jumpertz von Schwartzenberg R, Krakoff J. Peripheral Endocannabinoids Associated With Energy Expenditure in Native Americans of Southwestern Heritage.

    J Clin Endocrinol Metab. 2018 Mar 1;103(3):1077-1087. doi: 10.1210/jc.2017-02257. PMID: 29300902; PMCID: PMC6276675. https://doi.org/10.1210/jc.2017-02257
  • 2017

    Specific Skeletal Muscle Sphingolipid Compounds in Energy Expenditure Regulation and Weight Gain in Native Americans of Southwestern Heritage

    Heinitz S, Piaggi P, Vinales KL, Basolo A, Spranger J, Piomelli D, Krakoff J, Jumpertz von Schwartzenberg R. Specific skeletal muscle sphingolipid compounds in energy expenditure regulation and weight gain in Native Americans of Southwestern heritage.

    Int J Obes (Lond). 2017 Oct;41(10):1585-1593. doi: 10.1038/ijo.2017.143. Epub 2017 Jun 13. PMID: 28607453; PMCID: PMC5626585. https://doi.org/10.1038/ijo.2017.143
  • 2017

    Caloric Restriction in Older Adults-Differential Effects of Weight Loss and Reduced Weight on Brain Structure and Function

    Prehn K, Jumpertz von Schwartzenberg R, Mai K, Zeitz U, Witte AV, Hampel D, Szela AM, Fabian S, Grittner U, Spranger J, Flöel A. Caloric Restriction in Older Adults-Differential Effects of Weight Loss and Reduced Weight on Brain Structure and Function.

    Cereb Cortex. 2017 Mar 1;27(3):1765-1778. doi: 10.1093/cercor/bhw008. PMID: 26838769. https://doi.org/10.1093/cercor/bhw008
  • 2017

    Specific skeletal muscle sphingolipid compounds in energy expenditure regulation and weight gain in Native Americans of Southwestern heritage

    Heinitz S, Piaggi P, Vinales KL, Basolo A, Spranger J, Piomelli D, Krakoff J, Jumpertz von Schwartzenberg R. Specific skeletal muscle sphingolipid compounds in energy expenditure regulation and weight gain in Native Americans of Southwestern heritage.

    Int J Obes (Lond). 2017 Oct;41(10):1585-1593. doi: 10.1038/ijo.2017.143. Epub 2017 Jun 13. PMID: 28607453; PMCID: PMC5626585. https://doi.org/10.1038/ijo.2017.143
  • 2017

    Caloric Restriction in Older Adults-Differential Effects of Weight Loss and Reduced Weight on Brain Structure and Function

    Prehn K, Jumpertz von Schwartzenberg R, Mai K, Zeitz U, Witte AV, Hampel D, Szela AM, Fabian S, Grittner U, Spranger J, Flöel A. Caloric Restriction in Older Adults-Differential Effects of Weight Loss and Reduced Weight on Brain Structure and Function.

    Cereb Cortex. 2017 Mar 1;27(3):1765-1778. doi: 10.1093/cercor/bhw008. PMID: 26838769. https://doi.org/10.1093/cercor/bhw008
  • 2016

    Weight Loss Partially Restores Glucose-Driven Betatrophin Response in Humans

    Maurer L, Brachs S, Decker AM, Brachs M, Leupelt V, Jumpertz von Schwartzenberg R, Ernert A, Bobbert T, Krude H, Spranger J, Mai K. Weight Loss Partially Restores Glucose-Driven Betatrophin Response in Humans.

    J Clin Endocrinol Metab. 2016 Nov;101(11):4014-4020. doi: 10.1210/jc.2016-1788. Epub 2016 Jul 26. PMID: 27459526. https://doi.org/10.1210/jc.2016-1788
  • 2016

    ANP system activity predicts variability of fat mass reduction and insulin sensitivity during weight loss

    Brachs M, Wiegand S, Leupelt V, Ernert A, Kintscher U, Jumpertz von Schwarzenberg R, Decker AM, Bobbert T, Hübner N, Chen W, Krude H, Spranger J, Mai K. ANP system activity predicts variability of fat mass reduction and insulin sensitivity during weight loss.

    Metabolism. 2016 Jun;65(6):935-43. doi: 10.1016/j.metabol.2016.03.013. Epub 2016 Apr 7. PMID: 27173472. https://doi.org/10.1016/j.metabol.2016.03.013
  • 2015

    Palliative treatment of uncontrollable hypercalcemia due to parathyrotoxicosis: denosumab as rescue therapy

    Jumpertz von Schwartzenberg R, Elbelt U, Ventz M, Mai K, Kienitz T, Maurer L, Rose T, Rückert JC, Strasburger CJ, Spranger J. Palliative treatment of uncontrollable hypercalcemia due to parathyrotoxicosis: denosumab as rescue therapy.

    Endocrinol Diabetes Metab Case Rep. 2015;2015:150082. doi: 10.1530/EDM-15-0082. Epub 2015 Oct 29. PMID: 26605043; PMCID: PMC4653612. https://doi.org/10.1530/edm-15-0082
  • 2015

    Neuromodulation targeted to the prefrontal cortex induces changes in energy intake and weight loss in obesity

    Gluck ME, Alonso-Alonso M, Piaggi P, Weise CM, Jumpertz-von Schwartzenberg R, Reinhardt M, Wassermann EM, Venti CA, Votruba SB, Krakoff J. Neuromodulation targeted to the prefrontal cortex induces changes in energy intake and weight loss in obesity.

    Obesity (Silver Spring). 2015 Nov;23(11):2149-56. doi: 10.1002/oby.21313. PMID: 26530931; PMCID: PMC4636021. https://doi.org/10.1002/oby.21313
  • 2015

    Siri, What Should I Eat?

    Jumpertz von Schwartzenberg R, Turnbaugh PJ. Siri, What Should I Eat?

    Cell. 2015 Nov 19;163(5):1051-1052. doi: 10.1016/j.cell.2015.11.012. PMID: 26590412. https://doi.org/10.1016/j.cell.2015.11.012
  • 2013

    Food label accuracy of common snack foods

    Jumpertz R, Venti CA, Le DS, Michaels J, Parrington S, Krakoff J, Votruba S. Food label accuracy of common snack foods.

    Obesity (Silver Spring). 2013 Jan;21(1):164-9. doi: 10.1002/oby.20185. PMID: 23505182; PMCID: PMC3605747. https://doi.org/10.1002/oby.20185
  • 2013

    Food label accuracy of common snack foods

    Jumpertz R, Venti CA, Le DS, Michaels J, Parrington S, Krakoff J, Votruba S. Food label accuracy of common snack foods.

    Obesity (Silver Spring). 2013 Jan;21(1):164-9. doi: 10.1002/oby.20185. PMID: 23505182; PMCID: PMC3605747. https://doi.org/10.1002/oby.20185
  • 2012

    Circulating anandamide and blood pressure in patients with obstructive sleep apnea

    Engeli S, Blüher M, Jumpertz R, Wiesner T, Wirtz H, Bosse-Henck A, Stumvoll M, Batkai S, Pacher P, Harvey-White J, Kunos G, Jordan J. Circulating anandamide and blood pressure in patients with obstructive sleep apnea.

    J Hypertens. 2012 Dec;30(12):2345-51. doi: 10.1097/HJH.0b013e3283591595. PMID: 23032139. https://doi.org/10.1097/hjh.0b013e3283591595
  • 2012

    Associations of fatty acids in cerebrospinal fluid with peripheral glucose concentrations and energy metabolism

    Jumpertz R, Guijarro A, Pratley RE, Mason CC, Piomelli D, Krakoff J. Associations of fatty acids in cerebrospinal fluid with peripheral glucose concentrations and energy metabolism.

    PLoS One. 2012;7(7):e41503. doi: 10.1371/journal.pone.0041503. Epub 2012 Jul 24. PMID: 22911803; PMCID: PMC3404019. https://doi.org/10.1371/journal.pone.0041503
  • 2011

    Energy-balance studies reveal associations between gut microbes, caloric load, and nutrient absorption in humans

    Jumpertz R, Le DS, Turnbaugh PJ, Trinidad C, Bogardus C, Gordon JI, Krakoff J. Energy-balance studies reveal associations between gut microbes, caloric load, and nutrient absorption in humans.

    Am J Clin Nutr. 2011 Jul;94(1):58-65. doi: 10.3945/ajcn.110.010132. Epub 2011 May 4. PMID: 21543530; PMCID: PMC3127503. https://doi.org/10.3945/ajcn.110.010132
  • 2011

    Higher energy expenditure in humans predicts natural mortality

    Jumpertz R, Hanson RL, Sievers ML, Bennett PH, Nelson RG, Krakoff J. Higher energy expenditure in humans predicts natural mortality.

    J Clin Endocrinol Metab. 2011 Jun;96(6):E972-6. doi: 10.1210/jc.2010-2944. Epub 2011 Mar 30. PMID: 21450984; PMCID: PMC3100751. https://doi.org/10.1210/jc.2010-2944
  • 2011

    Energy-balance studies reveal associations between gut microbes, caloric load, and nutrient absorption in humans

    Jumpertz R, Le DS, Turnbaugh PJ, Trinidad C, Bogardus C, Gordon JI, Krakoff J. Energy-balance studies reveal associations between gut microbes, caloric load, and mpertz Rnutrient absorption in humans.

    Am J Clin Nutr. 2011 Jul;94(1):58-65. doi: 10.3945/ajcn.110.010132. Epub 2011 May 4. PMID: 21543530; PMCID: PMC3127503. https://doi.org/10.3945/ajcn.110.010132
  • 2011

    Central and peripheral endocannabinoids and cognate acylethanolamides in humans: association with race, adiposity, and energy expenditure

    Jumpertz R, Guijarro A, Pratley RE, Piomelli D, Krakoff J. Central and peripheral endocannabinoids and cognate acylethanolamides in humans: association with race, adiposity, and energy expenditure.

    J Clin Endocrinol Metab. 2011 Mar;96(3):787-91. doi: 10.1210/jc.2010-2028. Epub 2010 Dec 22. Erratum in: J Clin Endocrinol Metab. 2011 Jun 1;96(6):1908. PMID: 21177788; PMCID: PMC3047230. https://doi.org/10.1210/jc.2010-2028
  • 2011

    Central and peripheral endocannabinoids and cognate acylethanolamides in humans: association with race, adiposity, and energy expenditure

    Jumpertz R, Guijarro A, Pratley RE, Piomelli D, Krakoff J. Central and peripheral endocannabinoids and cognate acylethanolamides in humans: association with race, adiposity, and energy expenditure.

    J Clin Endocrinol Metab. 2011 Mar;96(3):787-91. doi: 10.1210/jc.2010-2028. Epub 2010 Dec 22. Erratum in: J Clin Endocrinol Metab. 2011 Jun 1;96(6):1908. PMID: 21177788; PMCID: PMC3047230. https://doi.org/10.1210/jc.2010-2028
  • 2011

    Higher energy expenditure in humans predicts natural mortality

    Jumpertz R, Hanson RL, Sievers ML, Bennett PH, Nelson RG, Krakoff J. Higher energy expenditure in humans predicts natural mortality.

    J Clin Endocrinol Metab. 2011 Jun;96(6):E972-6. doi: 10.1210/jc.2010-2944. Epub 2011 Mar 30. PMID: 21450984; PMCID: PMC3100751. https://doi.org/10.1210/jc.2010-2944
  • 2010

    Assessment of non-insulin-mediated glucose uptake: association with body fat and glycemic status

    Jumpertz R, Thearle MS, Bunt JC, Krakoff J. Assessment of non-insulin-mediated glucose uptake: association with body fat and glycemic status.

    Metabolism. 2010 Oct;59(10):1396-401. doi: 10.1016/j.metabol.2010.01.006. Epub 2010 Feb 12. PMID: 20153490; PMCID: PMC2894300. https://doi.org/10.1016/j.metabol.2010.01.006
  • 2010

    Circulating endocannabinoids and N-acyl-ethanolamides in patients with sleep apnea--specific role of oleoylethanolamide

    Jumpertz R, Wiesner T, Blüher M, Engeli S, Bátkai S, Wirtz H, Bosse-Henck A, Stumvoll M. Circulating endocannabinoids and N-acyl-ethanolamides in patients with sleep apnea--specific role of oleoylethanolamide.

    Exp Clin Endocrinol Diabetes. 2010 Oct;118(9):591-5. doi: 10.1055/s-0030-1253344. Epub 2010 Apr 28. PMID: 20429051. https://doi.org/10.1055/s-0030-1253344