Our research focus is metabolomics and systems medicine by application of advanced analytical techniques within preclinical and clinical research. For that we have specialized in chromatography, mass spectrometry and NMR spectroscopy and the use of metabolomics and lipidomics for systems biology and personalized medicine. Our expertise covers the complete workflow from sample preparation to analytical data acquisition, including QC measures, until statistical evaluation. The methodology of the lab ranges from ex-vivo tissue, feces/stool and cell culture investigations under application of two-phase extraction SOPs for polar and lipid metabolites until quantitative analysis of murine and human biofluids such as serum, urine and CSF. Using established SOPs and assays we are involved in a wide range of research projects in the realms of cancer, neurology, immunology, metabolic disorders and cardiovascular diseases.
Metabolomics & Systems Medicine
Head of Core Facility Metabolomics, Research Group Leader WSIC/M3
Publications: ORCID Profile
Publications: Web of Science
Biosketch
Christoph Trautwein finished his first degree at the University Stuttgart in 2006 as environmental engineer (Dipl.-Ing.) where he specialized in analytical chemistry and environmental microbiology. Awarded with a scholarship from the German Environmental Agency (DBU) he started his PhD in 2007 at the University of Freiburg in collaboration with the University Hospital Freiburg. Herein he investigated the microbial degradation and distribution of drugs in the aquatic environment using chromatography coupled with ion trap and triple quadrupole mass spectrometry. Fascinated by the potential use of advanced analytical chemistry within clinical resaerch, he started a second career in Molecular Medicine at the same time. Christoph Trautweil obtained his doctor title in 2012 (Dr. rer. nat.) and graduated in 2014 as Dipl. mol. med. at the University of Freiburg. In order to expand his analytical knowledge towards NMR spectroscopy, he was working from 2015-2016 at the Karlsruhe Institute for Technology (KIT) as postdoc for NMR based metabolomics. In 2017, he joined the WSIC at the University Hospital Tübingen and since then build up the research field of preclinical and clinical metabolomics including a magnitude of internal and external collaborations. Since 2019 he is heading his own research group supported by the WSIC foundation and proper 3rd party funding. Currently he is in process of finalizing his habilitation and assembling the new metabolomics core facility at the M3 center equipped with latest ion mobility mass spectrometry and MALDI-2 technology.
Team
Core Facility Metabolomics, Akademische Mitarbeiter
Publications: LinkedIn profile
MALDI Imaging Postdoc
Publications: ORCID profile
ex-vivo tissue
feces/stool and cell culture investigations
two-phase
extraction SOPs for polar and lipid metabolites
analysis
of murine and human biofluids