Das Klinikum

PD Dr.Dr. Ekkehard Sturm

PD Dr.Dr. Ekkehard Sturm

Oberarzt, Leiter Kindergastroenterologie/ -hepatologie

Kontakt

Telefonnummer: Sekretariat Kindergastroenterologie: 07071 29-81328

Faxnummer: 07071 29-4461

E-Mail-Adresse: ekkehard.sturm@med.uni-tuebingen.de

  • Kindergastroenterologie/ - hepatologie
  • Transplantationsmedizin
  • Ekkehard Sturm is currently leading the Pediatric Gastroenterology/ Hepatology group, University of Tuebingen, Children´s Hospital. This tertiary care facility is one of the largest national programs for pediatric liver transplantation. Research interests include Rare Liver Diseases and Liver Transplantation and Immunomodulation. His research interests are focussed on pathophysiology of cholestastic liver diseases, novel therapies including modifiers of the enterohepatic circulation and mesenchymal stroma cells for immmune-modulatory purposes. He was co-coordinator of the European Reference Network Rare Liver 2017-2021 and is leading the center for rare liver diseases at UK Tübingen.

  • Research interests:
    - management and pathophysiology of cholestastic liver diseases
    - novel therapies for peadiatric liver disease including modifiers of the enterohepatic circulation and gene therapy
    - mesenchymal stroma cells for immmune-modulatory purposes.
    - principal investigator of clinical trials
  • 1991- 1995Weiterbildung Facharzt Kinder- und Jugendmedizin, UKE Hamburg
  • 1995- 1998Weiterbildung Schwerpunkt Kindergastroenterologie/ -hepatologie, UKE Hamburg
  • 1998- 2000Forschungsaufenthalt, DFG Stipendium, Yale University, USA
  • 2000- 2006Oberarzt, Koordinator Programm Kinderlebertransplantation UMC Groningen, Niederlande
  • 2006-2011Oberarzt, Leiter Programm Kinderleber- und Darmtransplantation, UK Tübingen
  • seit 2011Oberarzt, Leiter Kindergastroenterologie/ -hepatologie
  • Gastrointestinal Research Award 2004 for PhD Thesis "Causes and Consequences of Cholestasis" awarded by The Dutch Society for Gastroenterology (NVGE), presented by Astra Zeneca
  • Helmut-Werner Award 2009 for extraordinary achievements in organ transplantation in children, presented by „Kinderhilfe Organtransplantation“
  • Julius-Springer Award 2011 for best biannual pediatric review Liver Diseases in Infants (Monatsschrift Kinderheilkunde, November 2010), presented by Springer Publishing
  • Poster Award FALK Symposium, Scheveningen, The Netherlands, 2000
  • Selected Publications:
  • Aldrian D, Vogel GF, Frey TK, Aksu AÜ, Civan HA, Avitzur Y, Ramos Boluda E, Çakır M, Demir AM, Deppisch C, Duba HC, Düker G, Gerner P, Hertecant J, Hornová J, Kathemann S, Koeglmeier J, Koutroumpa A, Lanzersdorfer R, Lev-Tzion R, Lima R, Meissl M, Melek J, Miqdady M, Montoya JH, Posovszky C, Rachman Y, Siahanidou T, Tabbers M, Uhlig H, Wirth S, Rümmele F, Hess MW, Huber LA, Müller T, Ekkehard Sturm*, Andreas R Janecke* (*equally contributing) Congenital diarrhea and cholestatic liver disease: phenotypic spectrum associated with MYO5B mutations. Journal of Clinical Medicine 2021
  • Gonzales E, Hardikar W, Stormon M, Baker A, Hierro L, Gliwicz D, Lacaille F, Lachaux A, Sturm E, Setchell K, Kennedy C, Dorenbaum A, Steinmetz J, Desai N, Wardle AJ, Vig P, Jaecklin T, Sokal E; Jacquemin E. Maralixibat treatment significantly reduces pruritus and serum bile acids in patients with Alagille syndrome: Results from a randomized Phase II study with 4 years of follow-up. Lancet, accepted for publication
  • Slavetinsky C, Sturm E. Odevixibat and partial external biliary diversion showed equal improvement ofcholestasis in a patient with progressive familial intrahepatic cholestasis. BMJ Case Rep. 29;13(6):e234185 2020
  • van Wessel DBE, Thompson RJ, Gonzales E, Jankowska I, Sokal E, Grammatikopoulos T, Kadaristiana A, Jacquemin E, Spraul A, Lipiński P, Czubkowski P, Rock N, Shagrani M, Broering D, Algoufi T, Mazhar N, Nicastro E, Kelly DA, Nebbia G, Arnell H, Björn Fischler, Hulscher JBF, Serranti D, Arikan C, Polat E, Debray D, Lacaille F, Goncalves C, Hierro L, Muñoz Bartolo G, Mozer-Glassberg Y, Azaz A, Brecelj J, Dezsőfi A, Calvo PL, Grabhorn E, Sturm E, van der Woerd WJ, Kamath BM, Wang JS, Li L, Durmaz Ö, Onal Z, Bunt TMG, Hansen BE, Verkade HJ; NAtural course and Prognosis of PFIC and Effect of biliary Diversion (NAPPED) consortium. Genotype correlates with the natural history of severe bile salt export pump deficiency. J Hepatol. 2020; Feb 20:S0168-8278(20)30105-7, 2020
  • Busch A, Sturm E. Screening Endoscopy Contributes to Relevant Modifications of Therapeutic Regimen in Children with Intestinal Failure. J Pediatr Gastroenterol Nutr, 2018
  • Hartleif S, Schumm MA, Döring M, Mezger M, Lang P, Dahlke, MH, Riethmüller J, Königsrainer A, Handgretinger R, Nadalin S, Sturm E Safety and Tolerance of Donor-derived Mesenchymal Stem Cells in Pediatric Living-donor Liver Transplantation: the MYSTEP1 Study. Stem Cell Int; 2017:2352954, 2017.
  • Hartleif S, Lang P, Handgretinger R, Feuchtinger T, Fuchs J, Königsrainer A, Nadalin S, Sturm E Outcomes of pediatric identical-living donor liver and hematopoietic stem cell transplantation Pediatr Transplant. 2016 Nov;20(7):888-897, 2016.
  • Sturm E, Piersma FE, Tanner MS, Socha P, Roberts EA, Shneider BL Controversies and Variation in Diagnosing and Treating Children with Wilson Disease: Results of an International Survey. J Pediatr Gastroenterol Nutr. 2015
  • Allgemeine Gastroenterologie und Lebererkrankungen des Kindesalters
  • American Association for the Study of Liver Diseases (AASLD)
  • EASL – European Association for the Study of the Liver
  • European Society for Paediatric Gastroenterology Hepatology and Nutrition (ESPGHAN)
  • Deutsche Gesellschaft für Kinder- und Jugendmedizin e.V. (DGKJ)
  • Gesellschaft für Pädiatrische Gastroenterologie und Ernährung (GPGE)