Das Klinikum

Dr. rer. nat. Saskia Rudat

Lengerke Lab

Telefonnummer: 07071 29-80676

E-Mail-Adresse: saskia.rudat@med.uni-tuebingen.de

My overarching goal is to improve the treatment of leukemia patients through translational cancer research.

During my time as a PhD Student at the German Cancer Research Center (DKFZ) and the National Center for Tumor Diseases (NCT) in Heidelberg, and later as a Postdoctoral Research Fellow at the Wellcome Sanger Institute in Hinxton, Cambridgeshire, UK, my work has focused on identifying vulnerabilities in diverse types of leukemia, most notably acute myeloid leukaemia (AML). Ultimately, my work has lead to the proposals of novel mechanism-based targeted therapies for specific subtypes of AML as described in Rudat et al. (Leukemia 2018) and Supper, Rudat et al. (Nature Communications 2021).

In my current position as a Scientific Project Manager and Senior Staff Scientist in the Laboratory of Prof. Dr. med. Claudia Lengerke at the University Hospital Tübingen, I now coordinate all ongoing research projects, support new grant applications as well as pursue my own scientific research interests, which involve the identification of targetable mechanisms to enhance the NKG2DL-mediated immunogenicity of AML cells using CRISPR/Cas9 screens with the aim to ultimately improve natural killer (NK)-cell therapy for AML patients.

since 09/2024Scientific Project Manager and Senior Staff Scientist, University Hospital Tübingen, Tübingen, DE
09/2021-08/2024Scientific Project Manager and Postdoctoral Research Fellow, University Hospital Tübingen, Tübingen, DE
01/2018-07/2021Postdoctoral Research Fellow, Wellcome Sanger Institute, Hinxton, UK
11/2012-12/2017PhD Student, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, DE
05/2012-10/2012Research Assistant, University Hospital Ulm, Ulm, DE
10/2006-04/2012Diploma Student of Molecular Biology, Ulm University, Ulm, DE

YoungEHA Best Abstract Award in the category for Postdoctoral Research Trainees - Jun 2019, 24th Congress of the European Hematology Association (EHA)
Poster Prize Award - Dec 2016, 32nd Ernst Klenk Symposium in Molecular Medicine