Das Klinikum

Dr. Christopher R. Cederroth

Dr. Christopher R. Cederroth

Senior Scientist

Associate Professor in Translational Auditory Neuroscience

Kontakt

Telefonnummer: 07071 29-88177

E-Mail-Adresse: christopher.cederroth@uni-tuebingen.de

Klinik / Institut / Zentrum

  • Short Bio

    Christopher R. Cederroth is a biologist who obtained his PhD in 2009 at the University of Geneva (Switzerland). As a post-doc, he worked on hearing loss and tinnitus at the Rockefeller University and at the Karolinska Institutet, where he developed his pre-clinical and clinical research on hearing loss and tinnitus. In 2014, he obtains a faculty funded position at the Karolinska Institutet and creates the Laboratory of Translational Auditory Neurosciences. He obtains his "Docentur" in 2018 and becomes Associate Professor. In 2023, he joins the University Hospital of Tübingen where he aims at bridging animal and human research in order to elucidate the molecular mechanisms causing auditory neuropathy, hearing loss and tinnitus, develop new objective measures, and therapeutic approaches for their treatment. Since 2022, he is Editor-in-Chief of the Journal of the Association for Research in Otolaryngology.

  • Epidemiologie von Hörstörungen
  • Genetik von Taubheit und Tinnitus
  • Objektive Diagnose von Tinnitus
  • Zirkadiane Mechanismen
  • Pharmakologie und Therapie des Hörverlustes
  • Geraldine Dietz Fox Young Investigator Award from the Association for Research in Otolaryngology  2023
  • Research Prize in Tinnitus and Hearing 2020 – Deutsche Stiftung für Tinnitus und Hören Charité
  • Philippe Foundation Prize
  • Denber-Pinard Prize
  • Swiss Endocrinology Foundation Prize
  • Mathiesen BK*, Miyakoshi LM*, Cederroth CR, Tserga E, Versteegh CPC, Bork PAR, Hauglund NL, Gomolka RS, Mori Y, Edvall NK, Rouse S, Møllgård K, Holt JR, Nedergaard M, Canlon B. 2023 “Delivery of gene therapy through a cerebrospinal fluid conduit to rescue hearing” Science Translational Medicine. 15(702):eabq3916.
  • Jarach CM, Lugo A, Scala M, van den Brandt PA, Cederroth CR, Odone A, Garavello W, Schlee W, Langguth B, Gallus S. 2022. “Global Prevalence and Incidence of Tinnitus: A Systematic Review and Meta-analysis” JAMA Neurol. Aug 8;e222189.
  • Trpchevska N, Freidin M, Broer L, Oosterloo BC, Yao S, Zhou Y, Vona B, Bishop C, Bizaki-Vallaskangas A, Canlon B, Castellana F, Chasman D, Cherny S, Christensen K, Pina Concas M, Correa A, Elkon R, Estonian Biobank Research Team, Mengel-From J, Gao Y, Giersch ABS, Girotto G, Gudjonsson A, Gudnason V, Heard-Costa NL, Hertzano R, v. B. Hjelmborg J, Hjerling-Leffler J, Hoffman HJ, Kaprio J, Kettunen J, Krebs K, Kähler AK, Lallemend F, Launer LJ, Lee I, Leonard H, Li CM, Lowenheim H, Magnusson PKE, van Meurs J, Milani L, Morton CC, Mäkitie A, Nalls MA, Giovanni Nardone G, Nygaard M, Palviainen T, Pratt S, Quaranta N, Rämö J, Saarentaus E, Sardone R, Satizabal Barrera CL, Schweinfurth JM, Seshadri S, Shiroma E, Shulman E, Simonsick E, Spankovich C, Tropitzsch A, Lauschke VM, Sullivan PF, Goedegebure A, Cederroth CR*, Williams FMK*, Nagtegaal AP*. 2022. “Genome-wide association meta-analysis identifies 48 risk variants and highlights the role of the stria vascularis in age-related hearing impairment” American Journal of Human Genetics. 2;109(6):1077-1091.
  • Edvall NK, Mehraei G, Claeson M, Bulla J, Lazar A, Uhlen I, Schlee W, Leineweber C, Canlon B, Cederroth CR. 2022. “Alterations in auditory brainstem response as an electrophysiological biomarker that distinguishes occasional and constant tinnitus” Journal of Clinical Investigation, 132(5):e155094
  • Milon B, Shulman ED, So KS, Cederroth CR, Lipford EL, Sperber M, Sellon JB, Sarlus H, Pregernig G, Shuster B, Song Y, Mitra S, Orvis J, Margulies Z, Ogawa Y, Shults C, Depireux DA, Palermo AT, Canlon B, Burns J, Elkon R, Hertzano R. 2021 ”A cell-type-specific atlas of the inner ear transcriptional response to acoustic trauma” Cell Reports, 28;36(13):109758
  • Amanat S, Gallego-Martinez A, Sollini J, Perez-Carpena P, Espinosa-Sanchez JM, Aran I, Soto-Varela A, Batuecas-Caletrio A, Canlon B, May P, Cederroth CR, Lopez-Escamez JA. 2021. “Burden of rare variants in synaptic genes in patients with severe tinnitus: An exome based extreme phenotype study” EBioMedicine. 66:103309
  • GBD 2019 Hearing Loss Collaborators. 2021. “Hearing loss prevalence and years lived with disability, 1990-2019: findings from the Global Burden of Disease Study 2019” The Lancet. 397(10278):996-1009
  • Cederroth CR*, Park JS*, Basinou B*, Weger B, Kadri N, Magnusson AM, Gachon F and Canlon B. 2019. “Circadian regulation of cochlear sensitivity to noise via circulating glucocorticoids” Current Biology, 29(15):2477-2487.e6.
  • Cederroth CR, Albrecht A, Bass J, Brown SA, Dyhrfjeld-Johnsen J, Gachon F, Green CB, Hastings MH, Helfrich-Förster C, Hogenesch JB, Lévi F, Loudon A, Lundqvist G, Meijer JH, Rosbash M, Takahashi J, Young M, Canlon B. 2019. “Medicine in the fourth dimension” Cell Metabolism, 30(2):238-250
  • Lugo A, Trpchevska N, Liu X, Biswas R, Magnusson C, Gallus S, Cederroth CR. 2019. “Sex-specific influences of tinnitus on suicide attempt” JAMA Otol, 145(7):685-687
  • Cederroth CR, PirouziFard M, Trpchevska N, Idrizbegovic E, Canlon B, Sundqvist J, Sundqvist K, Zöller B. 2019. “Association of Genetic and Environmental Factors in Swedish Adoptees with Clinically Significant Tinnitus” JAMA Otol, 145(3):222-229
  • Maas IL, Brüggemann P, Requena Navarro T, Bulla J, Edvall NK, Szczepek AJ, Canlon B, Mazurek B, Lopez-Escamez JA and Cederroth CR. 2017. “Genetic susceptibility to bilateral tinnitus in a Swedish twin cohort” Genetics in Medicine, 19(9):1007-1012
  • Park JS*, Cederroth CR*, Basinou V*, Sweetapple L, Buijink R, Lundkvist GB, Michel S, Canlon B. 2017 “Differential Phase Arrangement of Cellular Clocks along the Tonotopic Axis of the Mouse Cochlea Ex Vivo.” Current Biology, 17;24(6):658-63
  • Meltser I*, Cederroth CR*, Basinou V, Savelyev S, Schmitz-Lundkvist G and Canlon B. 2014. “TrkB mediated protection against circadian sensitivity to noise trauma in the murine cochlea” Current Biology, 17;24(6):658-63
  • Cederroth CR, Canlon B, and Langguth B. 2013. “Hearing loss and tinnitus: are funders and industry listening?” Nature Biotechnology, 31(11):972-4
  • Publikation liste