Das Klinikum

Dr. rer. nat. Stefanie Dietz

Dr. rer. nat. Stefanie Dietz

Wissenschaftliche Mitarbeiterin/Postdoc

Labor für Neonatale Immunologie und Immuntoleranz

Kontakt

Telefonnummer: 07071 29-86268

Telefonnummer: 07071 29-64191

Faxnummer: 07071 29-4947

E-Mail-Adresse: stefanie.dietz@med.uni-tuebingen.de

Klinik / Institut / Zentrum

  • Posterpreis der Gesellschaft für Neonatologie und Pädiatrische Intensivmedizin (GNPI) 2022
  • Rühle J, Schwarz J, Dietz S, Rückle X, Schoppmeier U, Lajqi T, Poets CF, Gille C, Köstlin-Gille N. Impact of perinatal administration of probiotics on immune cell composition in neonatal mice. Pediatr Res. 2024 Jan 26. doi: 10.1038/s41390-024-03029-2. Epub ahead of print. PMID: 38278847.
  • Rühle, J.; Ginzel, M.; Dietz, S.; Schwarz, J.; Lajqi, T.; Beer-Hammer, S.; Poets, C.F.; Gille, C.; Köstlin-Gille, N. Depletion of Ly6G-Expressing Neutrophilic Cells Leads to Altered Peripheral T-Cell Homeostasis and Thymic Development in Neonatal Mice. Int. J. Mol. Sci. 2023, 24, 7763. https://doi.org/10.3390/ijms24097763
  • Schwarz, J., Rühle, J., Stephan, K., Dietz, S., Geißert, J., Schoppmeier, U., Frick, J. S. et al., Targeted deletion of HIF-1α in myeloid cells of neonatal mice: decreased accumulation of myeloid-derived suppressor cells and altered microbiome. Eur J Immunol. 2023;e2250144. https://doi.org/10.1002/eji.202250144
  • Lajqi, T.; Köstlin-Gille, N.; Bauer, R.; Zarogiannis, S.G.; Lajqi, E.; Ajeti, V.; Dietz, S.; Kranig, S.A.; Rühle, J.; Demaj, A.; Hebel, J.; Bartosova, M.; Frommhold, D.; Hudalla, H.; Gille, C. Training vs. Tolerance: The Yin/Yang of the Innate Immune System. Biomedicines 2023, 11, 766. https://doi.org/10.3390/biomedicines11030766
  • Rückle X, Rühle J, Judd L, Hebel J, Dietz S, Poets CF, Gille C, Köstlin-Gille N. Different probiotic strains alter human cord blood monocyte responses. Pediatr Res. 2022 Dec 7. doi: 10.1038/s41390-022-02400-5. PMID: 36476746.
  • Dietz S, Molnar K, Riedel H, Haag L, Spring B, Orlikowsky TW, Poets CF, Gille C, Köstlin-Gille N. Expression of immune checkpoint molecules on adult and neonatal T-cells. Immunol Res. 2022 Nov 23. doi: 10.1007/s12026-022-09340-6. PMID: 36417145.
  • Schlegel C., Liu K., Spring B. Dietz S., Poets C.F., Hudalla H., Lajqi T., Köstlin-Gille N. and Gille C. Decreased expression of hypoxia-inducible factor 1α (HIF-1α) in cord blood monocytes under anoxia. Pediatr Res (2022). https://doi.org/10.1038/s41390-022-02193-7
  • Lajqi, T.; Köstlin-Gille, N.; Hillmer, S.; Braun, M.; Kranig, S.A.; Dietz, S.; Krause, C.; Rühle, J.; Frommhold, D.; Pöschl, J.; Gille, C.; Hudalla, H. Gut Microbiota-Derived Small Extracellular Vesicles Endorse Memory-like Inflammatory Responses in Murine Neutrophils. Biomedicines 2022, 10, 442. https://doi.org/10.3390/biomedicines10020442
  • Molnar K., Riedel H., Schwarz J., Dietz S., Spring B., Haag L., Poets C.F., Gille C. and Köstlin-Gille N. Group B streptococci infection model shows decreased regulatory capacity of cord blood cells. Pediatr Res (2022). https://doi.org/10.1038/s41390-021-01880-1
  • Dietz S, Schwarz J, Velic A, González-Menéndez I, Quintanilla-Martinez L, Casadei N, Marmé A, Poets CF, Gille C and Köstlin-Gille N (2022) Human Leucocyte Antigen G and Murine Qa-2 Are Critical for Myeloid Derived Suppressor Cell Expansion and Activation and for Successful Pregnancy Outcome. Front. Immunol. 12:787468. doi: 10.3389/fimmu.2021.787468
  • Dietz S, Schwarz J, Rühle J, Schaller M, Fehrenbacher B, Marmé A, Schmid E, Peter A, Poets CF, Gille C and Köstlin-Gille N. Extracellular vesicles released by myeloid-derived suppressor cells from pregnant women modulate adaptive immune responses. Cell Immunol. 2021 Mar;361:104276. doi: 10.1016/j.cellimm.2020.104276.
  • Köstlin-Gille N, Dietz S, Schwarz J, Spring B, Pauluschke-Fröhlich J, Poets CF andGille C. HIF-1α-Deficiency in Myeloid Cells Leads to a Disturbed Accumulation of Myeloid Derived Suppressor Cells (MDSC) During Pregnancy and to an Increased Abortion Rate in Mice. Front Immunol. 2019 Feb 5;10:161. doi: 10.3389/fimmu.2019.00161.
  • Dietz S, Schwarz J, Vogelmann M, Spring B, Molnár K, Orlikowsky TW, Wiese F, Holzer U, Poets CF, Gille C and Köstlin-Gille N. Cord blood granulocytic myeloid-derived suppressor cells impair monocyte T cell stimulatory capacity and response to bacterial stimulation. Pediatr Res. 2019 Nov;86(5):608-615. doi: 10.1038/s41390-019-0504-7.
  • Publikationen