iFIT Lunch & Learn Session with Miram Cortese-Krott
Metabolic control of endothelial heterogeneity and plasticity
This talk will focus on how metabolic signals shape endothelial heterogeneity and plasticity across different tissue microenvironments, including metabolic liver disease and the erythroid bone marrow niche. These mechanisms share important features with tumor ecosystems, particularly with respect to metabolic rewiring and angiocrine regulation. Miriam Cortese-Krott will discuss endothelial metabolism as a common mechanistic framework linking cardiovascular, metabolic, and tumor-related processes. Although her expertise is primarily in endothelial biology rather than tumor biology, this research direction offers strong opportunities for interdisciplinary collaborations. Miriam Kortese-Krott's contribution to such efforts would be based on extensive expertise in primary endothelial cell biology, advanced mouse models, and the investigation of endothelial cell function in health and disease.
