Medizinische Klinik
Innere Medizin VII
Institut für Tropenmedizin, Reisemedizin, Humanparasitologie

811

Adresse: Wilhelmstraße 27
72074 Tübingen


Publikationen 2007

  • T. Chookajorn, R. Dzikowski, M. Frank, F. Li, A.Z. Jiwani, D.L. Hartl, K.W. Deitsch:Epigenetic memory at malaria virulence genes.Proceedings of the National Academy of Science of USA 104: 899-902 (2007)

  • P.I. Mayengue, Y. Kalmbach, S. Issifou, P.G. Kremsner, F. Ntoumi:No variation in the prevalence of point mutations in the Pfcrt and Pfmdr1 genes in isolates from Gabonese patients with uncomplicated and severe Plasmodium falciparum malaria.Parasitology Research 100: 487-493 (2007)

  • F. Seibold, A.B. Boldt, B. Seibold-Schmid, A.M. Schoepfer, B. Flogerzi, S. Müller, J.F.J. Kun: Deficiency for mannan-binding lectin is associated with antibodies to Saccharomyces cerevisiae in patients with Crohn's disease and their relatives.Gut 56: 152 (2007)

  • S. Belard, M. Kist, M. Ramharter:Travel-related Salmonella Agama, Gabon.Emerging Infectious Diseases 13: 790-791 (2007)

  • D. Burkhardt, J. Wiesner, N. Stoesser, M. Ramharter, A.C. Uhlemann, S. Issifou, H. Jomaa, S. Krishna, P.G. Kremsner, S. Borrmann:Delayed parasite elimination in human infections treated with clindamycin parallels 'delayed death' of Plasmodium falciparum.International Journal of Parasitology 37: 777-785 (2007)

  • S. Oyakhirome, S. Issifou, P. Pongratz, F. Barondi, M. Ramharter, J.F.J. Kun, M.A. Missinou, B. Lell, P.G. Kremsner:Randomized controlled trial of fosmidomycin-clindamycin versus sulfadoxine-pyrimethamine in the treatment of Plasmodium falciparum malaria.Antimicrobial Agents and Chemotherapy 51: 1869-1871 (2007)

  • R. Fendel, B. Mordmüller, A. Kreidenweiss, A. Rudat, C. Steur, C. Ambrosch, M. Kirstein, W.E. Berdel, P.G. Kremsner, C. Brandts:New method to quantify erythrophagocytosis by autologous monocytes.Cytometry 71A: 258-264 (2007)

  • S. Oyakhirome, M. Pötschke, N.G. Schwarz, J. Dörnemann, M. Laengin, C.O. Salazar, B. Lell, J.F.J. Kun, P.G. Kremsner, M.P. Grobusch:Artesunate-amodiaquine combination therapy for falciparum malaria in young Gabonese children.Malaria Journal 6: 29 (2007)

  • O. Ojurongbe, T.O. Ogungbamigbe, A.F. Fangbenro-Beyioku, R. Fendel, P.G. Kremsner, J.F.J. Kun:Rapid detection of Pfcrt and Pfmdr I mutations in Plasmodium falciparum isolates by FRET and in vivo response to chloroquine among children from Osogbo, Nigeria.Malaria Journal 6: 41 (2007)

  • E. Mavoungou, J. Held, L. Mewono, P.G. Kremsner:A Duffy binding-like domain is involved in the NKp30-mediated recognition of Plasmodium falciparum-parasitized erythrocytes by natural killer cells.Journal of Infectious Diseases 195: 1521-1531 (2007)

  • M. Frank, R. Dzikowski, B. Amulic, K. Deitsch:Variable switching rates of malaria virulence genes are associated with chromosomal position.Molecular Microbiology 64: 1486-1498 (2007)
  • B. Pouvelle, V. Matarazzo, C. Jurzynski, J. Nemeth, M. Ramharter, G. Roiugon, J. Gysin:Neural cell adhesion molecule, a new cytoadhesion receptor for Plasmodium falciparum-infected erythrocytes capable of aggregation.Infection and Immunity 75: 3516-3522 (2007)

  • C. Tena-Tomas, M.K. Bouyou-Akotet, E. Kendjo, M. Kombila, P.G. Kremsner, J.F.J. Kun:Prenatal immune responses to Plasmodium falciparum erythrocyte membrane protein 1 DBL-alpha domain in Gabon.Parasitology Research 101: 1045-1050 (2007)

  • G.A. Awandere, P.G. Kremsner, J.B. Hittner, C.C. Keller, I.A. Clark, J.B. Weinberg, D.J. Perkins:Higher production of peripheral blood macrophage migration inhibitory factor in healthy children with a history of mild malria relative to children with a history to severe malaria.American Journal of Tropical Medicine and Hygiene 76: 1033-1036 (2007)

  • C. Druml, P.G. Kremsner:The fight against malaria - this month in Vienna.Wiener Klinische Wochenschrift 119: 269-270 (2007)

  • M. Ndounga, P.I. Mayengue, R. Tahar, P.N. Casimiro, D.W. Matondo Maya, V.M. Mpassi, D.A. Malonga, F. Nsonde-Ntando, G. Mallanda, P. Ringwald, L.K. Basco, F. Ntoumi:Efficacy of sulfadoxine-pyrimethamine, amodiaquine, and sulfadoxine-pyrimethamine-amodiaquine combination for the treatment of uncomplicated falciparum malaria in the urban and suburban areas of Brazzaville (Congo).Acta Tropica 103: 163-171 (2007)

  • F. Seibold, A.B. Boldt, B. Seibold-Schmid, A.M. Schoepfer, B. Flogerzi, S. Muller, J.F. Kun:Association of deficiency for mannan-binding lectin with anti-mannan antibodies in Crohn's disease: A family study.Inflammatory Bowel Diseases 13: 1077-1082 (2007)

  • A. Robin, F. Brown, N. Bahamontes-Rosa, B. Wu, E. Beitz, J.F. Kun, S.L. Flitsch:Microwave-assisted ring opening of epoxides: A general route to the synthesis of 1-aminopropan-2-ols with anti malaria parasite activities.Journal of Medical Chemistry 50: 4243-4249 (2007)

  • S.I. Oyedeji, H.O. Awobode, G.C. Monday, E. Kendjo, P.G. Kremsner, J.F. Kun:Comparison of PCR-based detection of Plasmodium falciparum infections based on single and multicopy genes.Malaria Journal 6: 112 (2007)

  • J. Paul, S. Jeyaraj, S. Huber, G. Seebohm, C. Bohmer, F. Lang, P. Kremsner, J. Kun:Alterations in the cytoplasmatic domain of CLCN2 result in altered gating kinetics.Cellular Physiology and Biochemistry 20: 441-454 (2007)

  • C. Tena-Tomas, M.L. Pedroso, I.J. de Messias-Reason, P.G. Kremsner, J.F.J. Kun:Polymorphisms in the IFNAR1 gene in patients with chronic hepatitis C: outcome of combined IFN-alpha therapy.European Cytokine Network 18: 19-24 (2007)

  • T. Hänscheid, T.J. Egan, M.P. Grobusch:Haemozoin: from melatonin pigment to drug target, diagnostic tool, and immune modulator.Lancet Infectious Diseases 7: 675-685 (2007)

  • M. Ndounga, R. Tahar, L.K. Basco, P.N. Casimiro, D.A. Malonga, F. Ntoumi:Therapeutic efficacy of sulfadoxine-pyrimethamine and the prevalence of molecular markers of resistance in under 5-year olds in Brazzaville, Congo.Tropical Medicine and International Health 12: 1164-1171 (2007)

  • I.J. de Messias-Reason, A.B.W. Boldt, A.C.M. Braga, E. von Rosen Seeling Stahlke, L. Dornelles, L. Perreira-Ferrari, P.G. Kremsner, J.F.J. Kun:The association between mannan-binding lectin gene polymorphism and clinical leprosy: new insight into an old paradigma.Journal of Infectious Diseases 196: 1379-1385 (2007)

  • M. Ramharter, F.M. Kurth, S. Belard, M.K. Bouyou-Akotet, M. Mabika Mamfoumbi, S.T. Agnandji, M.A. Missinou, A.A. Adegnika, S. Issifou, N. Cambon, J.L. Heidecker, M. Kombila, P.G. Kremsner:Pharmacokinetics of two pediatric artesunate-mefloquine drug formulations in the treatment of uncomplicated falciparum malaria in Gabon.Journal of Antimicrobial Chemotherapy 60: 1091-1096 (2007)

  • M. Ramharter, K. Schuster, M.K. Bouyou-Akotet, A.A. Adegnika, K. Schmits, G. Mombo-Ngoma, S.T. Agnandji, J. Nemeth, S. Nzenze Afene, S. Issifou, I. Ndombi Onnas, M. Kombila, P.G. Kremsner:Malaria in pregnancy before and after the implementation of a national IPTp program in Gabon.American Journal of Tropical Medicine and Hygiene 77: 418-422 (2007)

  • A. van den Biggelaer, T.D. Hua, L.C. Rodrigues, P.G. Kremsner, M. Yazdanbakhsh, D. Kube:Genetic variation in IL-10 is associated with atopic reactivity in Gabonese schoolchildren.Journal of Allergy and Clinical Immunology 120: 973-975 (2007)

  • N. Bahamontes-Rosa, B. Wu, E. Beitz, P.G. Kremsner, J.F.J. Kun:Limited genetic diversity of the Plasmodium falciparum aquaglyceroporin gene.Molecular and Biochemical Parasitology 156: 255-257 (2007)

  • P.B. Matsiegui, M.A. Missinou, S. Issifou, M. Necek, E. Mavoungou:Ibuprofen does not affect levels of tumor necrosis factor-alpha and soluble tumor necrosis factor recetor types I and II in Gabonese children with uncomplicated Plasmodium falciparum malaria.European Cytokine Network 18: 23-27 (2007)

  • M.P. Grobusch, A. Egan, R.D. Gosling, R.D. Newman:Intermittent preventive therapy for malaria: progress and future directions.Current Opinion in Infectious Diseases 20: 613-620 (2007)

  • R. Dzikowski, F. Li, B. Amulic, A. Eisberg, M. Frank, S. Patel, T.E. Wellems, K.W. Deitsch:Mechanisms underlying mutually exclusive expression of virulence genes by malaria parasites.EMBO Reports 8: 959-965 (2007)

  • M.P. Dal-Bianco, K.B. Köster, U.D. Kombila, J.F.J. Kun, M.P. Grobusch, G.M. Ngoma, P.B. Matsiegui, C. Supan, C.L.O. Salazar, M.A. Missionou, S. Issifou, B. Lell, P. Kremsner:High prevalence of asymptomatic Plasmodium falciparum infection in Gabonese adults.American Journal of Tropical Medicine and Hygiene 77: 939-942 (2007)

  • M. Ramharter, A.A. Adegnika, S.T. Agnandji, P.B. Matsiegui, M.P. Grobusch, S. Winkler, W. Graninger, S. Krishna, M. Yazdanbakhsh, B. Mordmüller, B. Lell, M.A. Missinou, E. Mavoungou, S. Issifou, P.G. Kremsner:History and perspectives of medical research at the Albert Schweitzer Hospital in Lambarene, Gabon.Wiener Klinische Wochenschrift 119 (Supplement 3): 8-12 (2007)

  • M.P. Grobusch, B. Lell, N.G. Schwarz, J. Gabor, J. Dörnemann, M. Pötschke, S. Oyakhirome, G.C. Kiessling, M. Necek, M.U. Längin, P.K. Klouwenberg, A. Klöpfer, B. Naumann, H. Altun, S.T. Agnandji, J. Goesch, M. Decker, C.L.O. Salazar, C. Supan, D.U. Kombila, L. Borchert, K.B. Köster, P. Pongratz, A.A. Adegnika, I. von Glasenapp, S. Issifou, P.G. Kremsner:Intermittent preventive treatment against malaria in infants in Gabon - a randomized, double-blind, placebo-controlled trial.Journal of Infectious Diseases 196: 1595-1602 (2007)

  • E. van Riet, A.A. Adegnika, K. Retra, R. Vieira, A.G.M. Tielens, B. Lell, S. Issifou, F.C. Hartgers, G.F. Rimmelzwaan, P.G. Kremsner, M. Yazdanbakhsh:Cellular and humoral responses to influenza in Gabonese children living in rural and semi-urban areas.Journal of Infectious Diseases 196: 1671-1678 (2007)

  • P. Effa, A. Massougbodji, F. Ntoumi, F. Hirsch, H. Debois, M. Vicari, A. Derme, J.N. Kamoune, J. Nguembo, B. Impouma, J.P. Akue, A. Ehouman, A. Dieye, W. Kilama:Ethics committees in western and central Africa: concrete foundations.Developing World Bioethics 7: 136-142 (2007)

  • F. Ntoumi, D.P. Kwiatkowski, M. Diakite, T.K. Mutabingwa, P.E. Duffy:New interventions for malaria: Mining the human and parasite genomes.American Journal of Tropical Medicine and Hygiene 77 (Supplement 6): 270-275 (2007)

  • M. Esen, B. Mordmüller:Parasites and pregnancy.Wiener Klinische Wochenschrift 119: 681-684 (2007)

  • A.A. Adegnika, S.T. Agnandji, S.K. Chai, M. Ramharter, L. Breitling, E. Kendjo, S. Issifou, M. Yazdanbakhsh, M. Kombila, P.G. Kremsner:Increased prevalence of increased helminth infection during pregnancy in a Sub-Saharan African community.Wiener Klinische Wochenschrift 119: 712-716 (2007)

  • S. Issifou, E. Kendjo, M.A. Missinou, P.B. Matsiegui, A. Dzeing-Ella, F.A. Dissanami, M. Kombila, S. Krishna, P.G. Kremsner:Differences in presentation of severe malaria in urban and rural Gabon.American Journal of Tropical Medicine and Hygiene 77: 1015-1019 (2007)

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