Das Klinikum

Research area and expertise

My scientific interests focus on the tumor-directed immunity and how this knowledge can be exploited in anti-tumor immunotherapy. The team works on the identification and functional characterization of tumor antigen-specific T cells and on the understanding of anti-tumor T cell responses in cancer patients. These activities are closely linked to our involvement in the design, development and immune monitoring of anti-cancer vaccines. To achieve our aims, we have established a technical platform for testing and characterizing antigen-specific T cells and we have a number of strategic collaborations with local and international clinics and research groups working in the field of tumor- and pathogen-directed T cell immunity and immunotherapy. I am also a founding member of the International Immunoguiding Workgroup of the Cancer Immunotherapy Association (CIP/CIMT, www.cimt.eu/workgroups/CIP) which has pioneered the concept of assay harmonisation and immunoguiding.