Medizinische Klinik
Innere Medizin VII
Institut für Tropenmedizin, Reisemedizin, Humanparasitologie

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811

Adresse: Wilhelmstraße 27
72074 Tübingen

Anfahrt 

Publikationen 1996 - 2000

  • B. Greve, B. Lell, D. Luckner, D. Schmid, P.G. Kremsner:Malarial anaemia in African children associated with high oxygen-radical production.Lancet 355: 40-41 (2000)

  • P.S. Gao, H. Kawada, T. Kasamatsu, X.Q. Mao, M.H. Roberts, Y. Miyamoto, M. Yoshimura, Y. Saitoh, H. Yasue, K. Nakao, C.N. Adra, J.F. Kun, S. Morooka, H. Inoko, L.P. Ho, T. Shirakawa, J.M. Hopkin:Variants of NOS1, NOS2 and NOS3 genes in asthmatics.Biochemical and Biophysical Research Communications 267: 761-763 (2000)

  • A. Barragan, P.G. Kremsner, M. Wahlgren, J. Carlson:Blood group A antigen is a coreceptor in Plasmodium falciparum malaria.Infection and Immunity 68: 2971-2975 (2000)

  • P.G. Kremsner:Malaria in central Europe: fears and factsWiener Klinische Wochenschrift 112: 421-422 (2000)

  • E.K. Sylla, B. Lell, P.G. Kremsner:A blinded, controlled trial of an ultrasound device as mosquito repellent.Wiener Klinische Wochenschrift 112: 448-450 (2000)

  • B. Lell, B. Vu-Quoc, P.G. Kremsner:Effect of alcohol on growth of Plasmodium falciparum.Wiener Klinische Wochenschrift 112: 451-452 (2000)

  • D.J. Conway, D.R. Cavanagh, K. Tanabe, C. Roper, Z.S. Mikes, N. Sakihama, K.A. Bojang, A.M.J. Oduola, P.G. Kremsner, D.E. Arnot, B.M.Greenwood, J.S. McBride:A principal target of human immunity to malaria identified by molecular population genetic and immunological analysis.Nature Medicine 6: 689-692 (2000)

  • B. Lell, J.F. Faucher, M.A. Missinou, S. Borrmann, O. Dangelmaier, J. Horton, P.G. Kremsner:Malaria chemoprophylaxis with tafenoquine: a randomised study.Lancet 355: 2041-2045 (2000)

  • A.J.F. Luty, D.J. Perkins, B. Lell, R. Schmidt-Ott, L.G. Lehman, D. Luckner, B. Greve, P. Matousek, K. Herbich, D. Schmid, J.B. Weinberg, P.G. Kremsner:Low interleukin-12 activity in severe Plasmodium falciparum malaria.Infection and Immunity 68: 3909-3915 (2000)

  • M.H. Deininger, P.G. Kremsner, R. Meyermann, H.J. Schluesener:Focal accumulation of cyclooygenase-1 (COX-1) and COX-2 expressing cells in cerebral malaria.Journal of Neuroimmunology 106: 198-205 (2000)

  • M.H. Deininger, P.G. Kremsner, R. Meyermann, H.J. Schluesener:Differential cellular accumulation of transforming growth factor-beta1, -beta2, -beta3 in brains of patients who died with cerebral malaria.Journal of Infectious Diseases 181: 2111-2115 (2000)

  • A.H.J. van den Biggelaer, J.L. Grogan, Y. Filie, R. Jordens, P.G. Kremsner, F. Koning, M. Yazdanbakhsh:Chronic schistosomiasis: dendritic cells generated from patients can overcome antigen-specific T cell hyporesponsiveness:Journal of Infectious Diseases 182: 260-265 (2000)

  • M.A. Missinou, O. Dangelmaier, J.F.J. Kun, P.G. Kremsner:Genetic diversity of Plasmodium falciparum infections in one family in Lambarene.Transactions of the Royal Society of Tropical Medicine and Hygiene 94: 376 (2000)

  • S. Jüliger, D. Luckner, B. Mordmüller, J. May, A. Weierich, B. Lell, A. Luty, P.G. Kremsner, J.F.J. Kun:Promoter variants of the human mannose-binding lectin gene show different binding.Biochemical and Biophysical Research Communications 275: 617-622 (2000)

  • J. Klabunde, J. Berger, J.C. Jensenius, M.Q. Klinkert, U.E. Zelck, P.G. Kremsner, J.F.J. Kun:Schistosoma mansoni: Adhesion of mannan-binding lection to surface glycoproteins of cercariae and adult worms.Experimental Parasitology 95: 231-239 (2000)

  • C.H. Brandts, W.H. Wernsdorfer, P.G. Kremsner:Decreasing chloroquine resistance in Plasmodium falciparum isolates from Gabon.Transactions of the Royal Society of Tropical Medicine and Hygiene 94: 554-556 (2000)

  • A.H.J. van den Biggelaer, R. van Ree, L.C. Rodrigues, B. Lell, A.M. Deelder, P.G. Kremsner, M. Yazdanbakhsh:Decreased atopy in children infected with Schistosoma haematobium: a role for parasite-induced interleukin-10.Lancet 356: 1723-1727 (2000)

  • E.H.K. Sylla, J.F.J. Kun, P.G. Kremsner:Mosquito distribution and entomological inoculation rates in three malaria-endemic areas in Gabon.Transactions of the Royal Society of Tropical Medicine and Hygiene 94: 652-656 (2000)

  • D.J. Perkins, J.B. Weinberg, P.G. Kremsner:Reduced interleukin-12 and transforming growth factor-beta1 in severe childhood malaria: Relationship of cytokine balance with disease severity.Journal of Infectious Diseases 182: 988-992 (2000)

  • J. May, B. Lell, A.J.F. Luty, C.G. Meyer, P.G. Kremsner:Plasma interleukin-10:tumor necrosis factor (TNF)-alpha ratio is associated with TNF promoter variants and predicts malarial complications.Journal of Infectious Diseases 182: 1570-1573 (2000)

  • B. Lell, C.H. Brandts, W. Graninger, P.G. Kremsner:The circadian rhythm of body temperature is preserved during malarial fever.Wiener Klinische Wochenschrift 112: 1014-1015 (2000)

  • S. Baize, E.M. Leroy, E. Mavoungou, S.P. Fisher-Hoch:Apoptosis in fatal Ebola infection: Does the virus steal the bell for immune system?Apoptosis 5: 5-7 (2000)

  • S. Fauser, M.H. Deininger, P.G. Kremsner, V. Magdolen, T. Luther, R. Meyermann, H.J. Schluesener:Lesion associated expression of urokinase-type plasminogen activator receptor (uPAR, CD87) in human cerebral malaria.Journal of Neuroimmunology 111: 234-240 (2000)

  • J. May, C.G. Meyer, A.G. Falusi, O.G. Ademowo, P.E. Olumese, L. Großterlinden, F.P. Mockenhaupt, L. Luzzatto, U. Bienzle: Red cell glucose-6-phosphat dehydrogenase status and pyruvat kinase activity in a Nigerian population. Tropical Medicine and International Health 5: 119-123 (2000)

  • J. May, F. Mockenhaupt, P.O. Ademowo, A.G. Falusi, P. Olumese, U. Bienzle, C. G. Meyer: Impact of subpatent multi-species and multi-clonal plasmodial infections on anaemia in children from Nigeria.Transactions of the Royal Society of Tropical Medicine and Hygiene 94: 399-403 (2000)

  • S. Hess, H. Smola, U.S. de Silva, D. Hadaschik, D. Kube, S.E. Baldus, U. Flucke, H. Pfister:Loss of IL-6 receptor expression in cervical carcinoma cells inhibits autocrine IL-6 stimulation: abrogation of constitutive monocyte chemoattractant protein-1 production.Journal of Immunology 165: 1339-1348 (2000)

  • F. Migot-Nabias, L.E. Mombo, A.J.F. Luty, B. Dubois, R. Nabias, C. Bisseye, P. Millet, C.Y. Lu, P. Deloron:Human genetic factors related to susceptibility to mild malaria in Gabon. Genes and Immunity 1: 435-441 (2000)

  • F. Migot-Nabias, P. Deloron, P. Ringwald, B. Dubois, J. Mayombo, T.N. Minh, N. Fievet, P. Millet, A.J.F. Luty: Immune response to Plasmodium falciparum liver stage antigen-1: geographical variations within Central Africa and their relationship with protection from clinical malaria. Transactions of the Royal Society of Tropical Medicine and Hygiene 94: 557-562 (2000)

  • M.T. Ekala, F. Lekoulou, S. Djikou, G. Dubreuil, S. Issifou, F. Ntoumi:Evaluation d'une methode simple et rapide d'extraction de l'AND de Plasmodium falciparum a partir de goute epaisses de patients gabonais.Bulletin de la Societe de Pathologie Exotique 93: 8-11 (2000)

  • A.J.F. Luty, S. Ulbert, B. Lell, L. Lehman, R. Schmidt-Ott, D. Luckner, B. Greve, P. Matousek, D. Schmid, K. Herbich, B. Dubois, P. Deloron, P.G. Kremsner:Antibody responses to Plasmodium falciparum: evolution according to the severity of a prior clinical episode and association with subsequent reinfection.American Journal of Tropical Medicine and Hygiene 62: 566-572 (2000)

  • A. Dabo, B. Doucoure, O. Koita, M. Diallo, B. Kouriba, M.Q. Klinkert, S. Doumbia, O. Doumbo:Reinfections par Schistosoma haematobium et mansoni a l'office du Niger au Mali malgre la prise repetee de praziquantel.Medecine Tropicale 60: 351-355 (2000)

  • F. Ntoumi, J. Ngoundou-Landji, F. Lekoulou, A. Luty, P. Deloron, P.Ringwald:Site-based study on polymorphism of Plasmodium falciparum MSP-1 and MSP-2 genes in isolates from two villages in Central Africa.Parassitologia 42: 197-203 (2000)

  • B. Mecozzi, A. Rossi, P. Lazzaretti, M. Kady, S. Kaiser, C. Valle, D. Cioli, M. Klinkert:Molecular cloning of Schistosoma mansoni calcineurin subunits and immunolocalization to the excretory system.Molecular and Biochemical Parasitology 110: 333-343 (1999)

  • S. Winkler, M. Willheim, K. Baier, D. Schmid, A. Aichelburg, W. Graninger, P.G. Kremsner:Frequency of cytokine-producing T cells in patients of different age groups with Plasmodium falciparum malaria.Journal of Infectious Diseases 179: 209-216 (1999)

  • A. Barragan, D. Spillmann, P.G. Kremsner, M. Wahlgren, J. Carlson:Plasmodium falciparum: Molecular background to strain-specific rosette disruption by glycosamoinoglycans and sulfated glycoconjugates.Experimental Parasitology 91: 133-143 (1999)

  • A.F.J. Luty, B. Lell, R. Schmidt-Ott, L.G. Lehman, D. Luckner, B. Greve, P. Matousek, K. Herbich, D. Schmid, F. Migot-Nabias, P. Deloron, R. S. Nussenzweig, P.G. Kremsner:Interferon-gamma responses are associated with resistance to reinfection with Plasmodium falciparum in young African children.Journal of Infectious Diseases 179: 980-988 (1999)

  • J. May, C.G. Meyer, J.F.J. Kun, B. Lell, D. Luckner, A.K. Dippmann, U. Bienzle, P.G. Kremsner:HLA class II factors associated with Plasmodium falciparum merozoite surface antigen allele families.Journal of Infectious Diseases 179: 1042-1045 (1999)

  • S. Looaresuwan, J.D. Chulay, C.J. Canfield, D.B.A. Hutchinson for the Malarone Clinical Trials Study Group: MalaroneTM (atovaquone and proguanil hydrochloride): A review of its clinical development for treatment of malaria.American Journal of Tropical Medicine and Hygiene 60: 533-541 (1999)

  • S. Winkler, M. Willheim, K. Baier, A. Aichelburg, P.G. Kremsner, W. Graninger:Increased frequency of Th2-type cytokine-producing T cells in microfilaremic loiasis.American Journal of Tropical Medicine and Hygiene 60: 680-686 (1999)

  • D.J. Conway, C. Roper, A.M.J. Oduola, D.E. Arnot, P.G. Kremsner, M.P. Grobusch, C.F.Curtis, B.M. Greenwood:High recombination rate in natural populations of Plasmodium falciparum.Proceedings of the National Academy of Sciences USA 96: 4506-4511 (1999)

  • B. Lell, J. May, R.J. Schmidt-Ott, L.G. Lehman, D. Luckner, B. Greve, P. Matousek, D. Schmid, K. Herbich, F.P. Mockenhaupt, C.G. Meyer, U. Bienzle, P.G. Kremsner:The role of red blood cell polymorphisms in resistance and susceptibility to malaria.Clinical Infectious Diseases 28: 794-799 (1999)

  • P.G. Kremsner, S. Looaresuwan, J.D. Chulay:Atovaquone and proguanil hydrochloride for treatment of malaria.Journal of Travel Medicine 6 (Supplement 1): S18-S20 (1999)

  • G.D. Shanks, P.G. Kremsner, T.Y. Sukwa, J.D. van der Berg, T.A. Shapiro, T.R. Scott, J.D. Chulay for the Malarone Clinical Trial Group:Atovaquone and proguanil hydrochloride for prophylaxis of malaria.Journal of Travel Medicine 6 (Supplement 1): S21-S27 (1999)

  • B. Greve, L.G. Lehman, B. Lell, D. Luckner, R. Schmidt-Ott, P.G. Kremsner:High oxygen radical production is associated with fast parasite clearance in children with Plasmodium falciparum malaria.Journal of Infectious Diseases 179: 1584-1586 (1999)

  • S. Winkler, M. Willheim, K. Baier, W. Graninger, P.G. Kremsner:Frequency of cytokine-producing CD4-CD8- peripheral blood mononuclear cells in patients with Plasmodium falciparum malaria.European Cytokine Network 10: 155-160 (1999)

  • J.F.J. Kun, L.G. Lehman, B. Lell, R. Schmidt-Ott, P.G. Kremsner:Low-dose treatment with sulfadoxine-pyrimethamine combinations selects for drug-resistant Plasmodium falciparum strains.Antimicrobial Agents and Chemotherapy 43: 2205-2208 (1999)

  • D.J. Perkins, P.G. Kremsner, D. Schmid, M.A. Misukonis, M.A. Kelly, J.B. Weinberg:Blood mononuclear cell nitric oxide production and plasma cytokine levels in healthy Gabonese children with prior mild or severe malaria.Infection and Immunity 67: 4977-4981 (1999)

  • J.F.J. Kun, J. Klabunde, B. Lell, D. Luckner, M. Alpers, J. May, C. Meyer, P.G. Kremsner:Association of the ICAM-1Kilifi mutation with protection against severe malaria in Lambaréné, Gabon.American Journal of Tropical Medicine and Hygiene 61: 776-779 (1999)

  • J.F.J. Kun, K.L. Waller, R.L. Coppel:Plasmodium falciparum: Structural and functional domains of the mature-parasite-infected erythrocyte surface antigen.Experimental Parasitology 91: 258-267 (1999)
  • A. Khattab, L.P. Mattoccia, R. Wenger, D. Cioli, M.Q. Klinkert:Assay of Schistosoma mansoni calcineurin phosphatase activity and assessment of its role in parasite survival.Molecular and Biochemical Parasitology 99: 269-273 (1999)

  • P. Deloron, P. Ringwald, A. Luty, A. Renaut, T.N. Minh, J.R. Mbessy, P. Millet:Relationships between malaria prevalence and malaria-related morbidity in schoolchildren from two villages from Central Africa.American Journal of Tropical Medicine and Hygiene 61: 99-102 (1999)

  • F. Migot- Nabias, A.J.F. Luty, P. Ringwald, M. Vaillant, B. Dubois, J. Mayombo, T.N. Minh, N. Fievet, J.R. Mbessi, P. Millet, P. Deloron:Immune response against Plasmodium falciparum blood stage antigens and disease susceptibility in Gabonese and Cameroonian children.American Journal of Tropical Medicine and Hygiene 61: 488-494 (1999)

  • D. Kube, H. Laser, A. von Knethen, H. Tesch:The AT-rich region between -54 to -66 is important for the promoter activity of interleukin-10 in Epstein-Barr Virus positive Burkitt's lymphoma.Genes and Immunity 1: 105-114 (1999)

  • P.A. Horn, H. Tesch, P. Staib, D. Kube, V. Diehl, D. Voliotis:Expression of AC133, a novel hematopoietic precursor antigen, on acute myeloid leukemia cells.Blood 93: 1435-1437 (1999)

  • D. Kube, M. Vockerodt, O. Weber, K. Hell, J. Wolf, B. Haier, F.A. Grässer, N. Müller-Lantzsch, E. Kieff, V. Diehl, H. Tesch:Expression of Epstein-Barr Virus nuclear antigen 1 is associated with enhanced expression of CD25 in the Hodgkin cell line L428.Journal of Virology 73: 1630-1636 (1999)

  • G. Burbach, J. May, G. Harms, U. Bienzle: Leishmaniasis. Basic principles, clinical aspects, diagnosis and therapy. Deutsche Medizinische Wochenschrift 124: 88-93 (1999)

  • F.P. Mockenhaupt, U. Bienzle, J. May, A. Falusi, O.G. Ademowo, P.E. Olumese, C.G. Meyer:Plasmodium falciparum-infection: influence on hemoglobin levels ina-thalassemia and microcytosis. Journal of Infectious Diseases 180: 925-928 (1999)

  • J. May, F. Mockenhaupt, O.G. Ademowo, A.G. Falusi, P.E. Olumese, U. Bienzle, C.G. Meyer:High rate of mixed and subpatent malarial infections in southwest Nigeria. American Journal of Tropical Medicine and Hygiene 61: 339-343 (1999)

  • F.P. Mockenhaupt, J. May, T.A. Eggelte, F.L. Thies, O.G. Ademowo, U. Bienzle, C.G. Meyer:High prevalence and imbalanced age distribution of the Plasmodiumfalciparum dihydrofolate reductase Asn-108 mutation in an area of lowpyrimethamine usage in Nigeria. American Journal of Tropical Medicine and Hygiene 61: 375-377 (1999)

  • C.G. Meyer, J. May, T. Schwarz: Tropische Virosen. Deutsche Medizinische Wochenschrift 124: 1043-1051 (1999)

  • F.P. Mockenhaupt, A.G. Falusi, J. May, O.G. Ademowo, P.E. Olumese, C.G. Meyer, U. Bienzle: The contribution of alpha+-thalassaemia to anaemia in a Nigerianpopulation exposed to intense malaria transmission. Tropical Medicine and International Health 4:302-307 (1999)

  • F. Mockenhaupt, J. May, K. Stark, A.G. Falusi, C.G. Meyer, U. Bienzle: Serum transferrin receptor levels in Plasmodium falciparum-infection. Hematologica 84: 869-873 (1999)

  • C. Lindenthal, E.A. Elsinghorst: Identification of a glycoprotein produced by enterogenic Escherichia coli.Infection and Immunity 67: 4084-4091 (1999)

  • L.G. Lehman, J. Prada, P.G. Kremsner:Protection of mice previously infected with Plasmodium vinckei against subsequent Salmonella enteritidis infection is associated with nitric oxide production capacity.Parasitology Research 60: 63-68 (1998)

  • J.F.J. Kun, R.J. Schmidt-Ott, L.G. Lehman, B. Lell, D. Luckner, B. Greve, P. Matousek, P.G. Kremsner:Merozoite surface antigen 1 and 2 genotypes and rosetting of Plasmodium falciparum in severe and mild malaria in Lambaréné, Gabon.Transactions of the Royal Society of Tropical Medicine and Hygiene 92: 110-114 (1998)

  • J.F.J. Kun, B. Mordmüller, B. Lell, L.G. Lehman, D. Luckner, P.G. Kremsner:Polymorphism in promoter region of inducible nitric oxide synthase gene and protection against malaria.Lancet 351: 265-266 (1998)

  • C. Scholander, J. Carlson, P.G. Kremsner, M. Wahlgren:Extensive immunoglobulin binding of Plasmodium falciparum-infected erythrocytes in a group of children with moderate anemia.Infection and Immunity 66: 361-363 (1998)

  • B. Lell, D. Luckner, M. Ndjave, T. Scott, P.G. Kremsner:Randomised placebo-controlled study of atovaquone plus proguanil for malaria prophylaxis in children.Lancet 351: 709-713 (1998)

  • M.P. Grobusch, I.S. Adagu, P.G. Kremsner, D.C. Warhurst:Plasmodium falciparum: in vitro chloroquine susceptibility and allele-specific PCR detection of Pfmdr 1 Asn86Tyr polymorphism in Lambarene, Gabon.Parasitology 116: 211-217 (1998)

  • B. Halpaap, M. Ndjave, M. Paris, A. Benakis, P.G. Kremsner:Plasma levels of artesunate and dihydroartemisinin in children with Plasmodium falciparum malaria in Gabon after administration of 50-milligram artesunate suppositories.American Journal of Tropical Medicine and Hygiene 58: 365-368 (1998)

  • B. Mordmüller, W. Graninger, P.G. Kremsner:Die Malariatherapie in den Zeiten der Chloroquinresistenz.Wiener Klinische Wochenschrift 110: 321-325 (1998)

  • J. Philipps, P.D. Radloff, W. Wernsdorfer, P.G. Kremsner:Follow-up of the susceptibility of Plasmodium falciparum to antimalarials in Gabon.American Journal of Tropical Medicine and Hygiene 58: 612-618 (1998)

  • B. Lell, L.G. Lehman, J.R. Schmidt-Ott, D. Stürchler, J. Handschin, P.G. Kremsner:Malaria chemotherapy trial at a minimal effective dose of mefloquine/sulfadoxine/pyrimethamine compared with equivalent doses of sulfadoxine/pyrimethamine or mefloquine alone.American Journal of Tropical Medicine and Hygiene 58: 619-624 (1998)

  • B. Mordmüller, P.G. Kremsner:Hyperparasitemia and blood exchange transfusion for treatment of children with falciparum malaria.Clinical Infectious Diseases 26: 850-852 (1998)

  • C.W.A. Naus, G.J. van Dam, P.G. Kremsner, F.W. Krijger, A.M. Deelder:Human IgE, IgG subclass, and IgM responses to worm and egg antigens in schistosomiasis haematobium: A 12-month study of reinfection in Cameroonian children.Clinical Infectious Diseases 26: 1142-1147 (1998)

  • J.L. Grogan, P.G. Kremsner, A.M. Deelder, M. Yazdanbakhsh:Antigen-specific proliferation and interferon-? and interleukin-5 production are down-regulated during Schistosoma haematobium infection.Journal of Infectious Diseases 177: 1433-1437 (1998)

  • J.L. Grogan, P.G. Kremsner, A.M. Deelder, M. Yazdanbakhsh:The effect of anti-IL-10 on proliferation and cytokine production in human schistosomiasis: fresh versus cryopreserved cells.Parasite Immunology 20: 345-349 (1998)

  • J. May, P.G. Kremsner, D. Milovanovic, L. Schnittger, C.C. Löliger, U. Bienzle, C.G. Meyer:HLA-DP control of human Schistosoma haematobium infection.American Journal of Tropical Medicine and Hygiene 58: 619-624 (1998)

  • A.J.F. Luty, J.F.J. Kun, P.G. Kremsner:Mannose-bind

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