Medizinische Klinik
Innere Medizin VII
Institut für Tropenmedizin, Reisemedizin, Humanparasitologie

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Adresse: Wilhelmstraße 27
72074 Tübingen

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Publikationen 2011

  • A.A. Adegnika, A.J. Luty, M.P. Grobusch, M. Ramharter, M. Yazdanbakhsh, P.G. Kremsner, N. G. Schwarz: ABO blood group and the risk of placental malaria in sub-Saharan Africa.Malaria Journal 10: 101 (2011)

  • S.T. Agnandji, R. Fendel, M. Mestré, M, Janssens, J. Vekemans, J. Held, F. Gnansounou, S. Haertle, I. von Glasenapp, S. Oyakhirome, L. Mewono, Moris, M. Lievens, M.A. Demoitie, P.M.Dubois , T. Villafana, E. Jongert, A. Olivier, J. Cohen, M. Esen, P.G. Kremsner, B. Lell, B. Mordmüller: Induction of Plasmodium falciparum-specific CD4+ T cells and memory B cells in Gabonese children vaccinated with RTS,S/AS01(E) and RTS,S/AS02(D). PLoS One 6(4): e18559 (2011)

  • S.T. Agnandji, B. Lell, S.S. Soulanoudjingar, J.F. Fernandes, B.P. Abossolo, C. Conzelmann, B. G. Methogo, Y. Doucka, A. Flamen, B. Mordmüller, S. Issifou, P.G. Kremsner, J. Sacarlal, P. Aide, M. Lanaspa, J.J. Aponte, A. Nhamuave, D. Quelhas Q. Bassat, S. Mandjate, E. Macete, P. Alonso, S. Abdulla, N. Salim, O. Juma, M. Shomari, K. Shubis, F. Machera, A.S. Hamad, R. Minja, A. Mtoro, A. Sykes, S. Ahmed, A.M. Urassa, A.M. Ali, G. Mwangoka, M. Tanner, H. Tinto, U. D'Alessandro. H. Sorgho, I. Valea, M.C. Tahita, W. Kaboré, S. Ouédraogo, Y Sandrine, R.T. Guiguemdé, J.B. Ouédraogo, M.J. Hamel, S. Kariuki, C. Odero, M. Oneko, K. Otieno, N. Awino, J. Omoto, J. Williamson, V. Muturi-Kioi, K.F. Laserson, L. Slutsker, W. Otieno, L. Otieno, O. Nekoye, S. Gondi, A. Otieno, B. Ogutu, R. Wasuna, V. Owira, D. Jones, A.A. Onyango, P. Njuguna, R. Chilengi, P. Akoo, C. Kerubo, J. Gitaka, C. Maingi, T. Lang, A. Olotu, B. Tsofa, P. Bejon, N. Peshu, K. Marsh, S. Owusu-Agyei, K.P. Asante, K. Osei-Kwakye, O. Boahen, S. Ayamba, K. Kayan, R. Owusu-Ofori, D. Dosoo, I. Asante, G. Adjei, Adjei G, Chandramohan D, B. Greenwood, J. Lusingu, S. Gesase, A. Malabeja, O. Abdul, H. Kilavo, C. Mahende, E. Liheluka, M. Lemnge, T. Theander, C. Drakeley, D. Ansong, T. Agbenyega, S. Adjei, H.O. Boateng, T. Rettig, J. Bawa, J. Sylverken, D. Sambian, A. Agyekum, L. Owusu, F. Martinson, I. Hoffman, T. Mvalo, P. Kamthunzi, R. Nkomo, A. Msika, A. Jumbe, N. Chome, D. Nyakuipa, J. Chintedza, W.R. Ballou, M. Bruls, J. Cohen, Y Guerra, E. Jongert, D. Lapierre, A. Leach, M. Lievens, O.J. Ofori-Anyinam J. Vekemans, T. Carter, D. Leboulleux, C. Loucq, A. Radford, B. Savarese, D. Schellenberg, M. Sillman, P. Vansadia; RTS,S Clinical Trials Partnership:First results of phase 3 trial of RTS,S/AS01 malaria vaccine in African children.New England Journal of Medicine 365(20): 1863-1875 (2011)

  • S.T. Agnandji, F. Kurth, S. Bélard , G. Mombo-Ngoma, A. Basra, J.F. Fernandes, S.S. Soulanoudjingar, A.A. Adegnika, M. Ramharter:Current status of the clinical development and implementation of paediatric artemisinin combination therapies in Sub-Saharan Africa.Wiener Klinische Wochenschrift 123, Suppl. 1: 7-9 (2011)

  • S.T. Agnandji, F. Kurth, J.F. Fernandes, S. A. Soulanoudjingar, B.P. Abossolo, G. Mombo-Ngoma, A. Basra, G. , Kizito G, P.I. Mayengue, L. Auer-Hackenberg, S. Issifou, B. Lell, A.A. Adegnika, M. Ramharter:The use of paediatric artemisinin combinations in sub-Saharan Africa: a snapshot questionnaire survey of health care personnel.Malaria Journal 10(1): 365 (2011)

  • K.P. Asante, S. Abdulla, S. Agnandji, J. Lyimo, J. Vekemans, S. Soulanoudjingar, R. Owusu, M. Shomari, A. Leach, E. Jongert, N. Salim, J.F. Fernandes, D. Dosoo, M. Chikawe, S. Issifou, K. Osei-Kwakye, M. Lievens, M. Paricek, T. Möller, S. Apanga, G. Mwangoka, M.C. Dubois, T. Madi, E. Kwara, R. Minja, A.B. Hounkpatin, O. Boahen, K. Kayan, G. Adjei, D. Chandramohan, T. Carter, P. Vansadia, M. Sillman B. Savarese, C. Loucq, D. Lapierre, B. Greenwood, J. Cohen , P. Kremsner, S. Owusu-Agyei, M. Tanner, B. Lell:Safety and efficacy of the RTS,S/AS01E candidate malaria vaccine given with expanded-programme-on-immunisation vaccines: 19 month follow-up of a randomised, open-label, phase 2 trial.Lancet Infectious Diseases (10): 741-749 (2011)

  • E. Ayimba, J. Hegewald, A.Y. Ségbéna, R.G. Gantin, C.J. Lechner, A. Agosssou, M. Banla, P.T.Soboslay:Proinflammatory and regulatory cytokines and chemokines in infants with uncomplicated and severe Plasmodium falciparum malaria.Clinical and Experimental Immunology 166(2): 218-226 (2011)

  • S. Bélard , S. Issifou, A.B. Hounkpatin, F. Schaumburg, U. A. Ngoa, M. Esen, R. Fendel, P. M. de Salazar, R.E. Mürbeth, P. Milligan, N. Imbault, E.B. Imoukhuede, M. Theisen, S. Jepsen, R.A. Noor, B. Okech, P.G. Kremsner, B. Mordmüller: A Randomized Controlled Phase Ib Trial of the Malaria Vaccine Candidate GMZ2 in African Children. PLoS One 6(7): e22525 (2011)

  • A.B. Boldt, C. Grisbach, R. Steffensen, S. Thiel, J.F. Kun, J.C. Jensenius, I.J. Messias-Reason:Multiplex sequence-specific polymerase chain reaction reveals new MASP2 haplotypes associated with MASP-2 and MAp19 serum levels.Human Immunology 72(9): 753-760 (2011)

  • K. Bucher, K. Dietz, P. Lackner, B. Pasche, R. Fendel, B. Mordmüller, A. Ben-Smith, W.H. Hoffmann:Schistosoma co-infection protects against brain pathology but does not prevent severe disease and death in a murine model of cerebral malaria.International Journal of Parasitology 41(1): 21-31 (2011)

  • C. Enderes, D. Kombila, M. Dal-Bianco, R. Dzikowski, P. Kremsner, M. Frank:Var Gene Promoter Activation in Clonal Plasmodium falciparum Isolates Follows a Hierarchy and Suggests a Conserved Switching Program that Is Independent of Genetic Background. Journal of Infectious Diseases 204(10):1620-1631 (2011)

  • I. Faik, S.I. Oyedeji, Z. Idris, I.J. de Messias-Reason, B. Lell, P.G. Kremsner, J.F. Kun: Ficolin-2 levels and genetic polymorphisms of FCN2 in malaria. Human Immunology 72(1): 74-79 (2011)

  • Four Artemisinin-Based Combinations (4ABC) Study Group.D. Atwine, B. Balikagala, Q.Bassat, V. Chalwe, U. D'Alessandro, M. Dhorda, S. Donegan, P. Garner, R. González, R. Tinga Guiguemde, D. Kajungu, M. Kamya, C. Karema, A. Kibuuka, P.G. Kremsner, B.Lell, S. Machevo, C. Menéndez, J. Menten, M. Meremikwu, G. Mombo-Ngoma, F. Mudangha, M. Mulenga, T. Munyaneza, C. Nabasumba, M. Nambozi, F. Odey, S. Okello, C. Oringanje, A. Oyo-Ita, P. Piola, R. Ravinetto, N. Rouamba, F. Strecker, A.O. Talisuna, N. Umulisa, A. Uwimana, I. Valéa, J.P. Van Geertruyden, H. van Loen, P. Williamson, A.Yeka:A head-to-head comparison of four artemisinin-based combinations for treating uncomplicated malaria in African children: a randomized trial.PLoS Medicine 8(11): e1001119 (2011)

  • M. Frank, N. Lehners, P.I. Mayengue, J. Gabor, M. Dal-Bianco, D.U. Kombila, G. Mombo Ngoma, C. Supan, B. Lell, F. Ntoumi, M.P. Grobusch, K. Dietz, P.G. Kremsner: A thirteen-year analysis of Plasmodium falciparum populations reveals high conservation of the mutant pfcrt haplotype despite the withdrawal of chloroquine from national treatment guidelines in Gabon. Malaria Journal 10(1): 304 (2011)

  • R. Frita, M. Rebelo, A. Pamplona, A.M. Vigario, M.M.Mota, M.P. Grobusch, T. Hänscheid:Simple flow cytometric detection of haemozoin containing leukocytes and erythrocytes for research on diagnosis, immunology and drug sensitivity testing.Malaria Journal 10: 74 (2011)

  • S. Gabrysch, P. Zanger, H. R. Seneviratne, Mbewe R, O.M. Campbell.Tracking progress towards safe motherhood: meeting the benchmark yet missing the goal? An appeal for better use of health-system output indicators with evidence from Zambia and Sri Lanka.Tropical Medicine and International Health 16(5): 627-639 (2011)

  • E. Grangeiro de Carvalho, M. Bonin M, P.G. Kremsner, J.F. Kun:Plasmodium falciparum-Infected Erythrocytes and IL-12/IL-18 Induce Diverse Transcriptomes in Human NK Cells: IFN-?/? Pathway versus TREM Signaling.PLoS One 6(9): e24963 (2011)

  • E.G. de Carvalho, E. Böttger, V.T. Hoang, P.G. Kremsner, J.F. Kun:Limited response of NK92 cells to Plasmodium falciparum-infected erythrocytes.Malaria Journal 10: 311 (2011)

  • F. Hamid, A.E. Wiria, L.J. Wammes, M.M. Kaisar, B. Lell, I. Ariawan, W.H. Uh, H. Wibowo, Y. Djuardi, S. Wahyuni, R. Schot, J.J. Verweij, R. van Ree, L. May, E. Sartono, M. Yazdanbakhsh, T. Supali: A longitudinal study of allergy and intestinal helminth infections in semi urban and rural areas of Flores, Indonesia (ImmunoSPIN Study).BMC Infectious Diseases 11: 83 (2011)

  • S.A. Hanel, Velavan TP, P.G. Kremsner, J.F. Kun: Novel and functional regulatory SNPs in the promoter region of FOXP3 gene in a Gabonese population. Immunogenetics 63(7): 409-415 (2011)

  • J. Held, S.S. Soomro, P.G. Kremsner, F.H. Jansen, B. Mordmüller: In vitro activity of new artemisinin derivatives against Plasmodium falciparum clinical isolates from Gabon. International Journal of Antimicrobial Agents 37(5): 485-488 (2011)

  • A.A. Hogewoning, A.A. Adegnika, J.N. Bouwes Bavinck, M. Yazdanbakhsh, P.G. Kremsner, E.M. van der Raaij-Helmer, C.C. Staats, R. Willemze, A.P. Lavrijsen:Prevalence and causative fungal species of tinea capitis among schoolchildren in Gabon.Mycoses 54(5): e354-359 (2011)

  • A. Humberg, J. Kammer, B. Mordmüller, P.G. Kremsner, B. Lell: Haematological and biochemical reference intervals for infants and children in Gabon. Tropical Medicine and International Health 16(3): 343-8 (2011)

  • Z.M. Idris, N. Miswan, J. Muhi, T.A. Mohd, J.F. Kun, R. Noordi:Association of CTLA4 gene polymorphisms with lymphatic filariasis in an East Malaysian population. Human Immunology 72(7): 607-612 (2011)

  • C. Köhler, A.A. Adegnika, R.A. van der Linden, A.J. Luty, P.G. Kremsner: Phenotypic characterization of mononuclear blood cells from pregnant Gabonese and their newborns. Tropical Medicine and International Health 16(9): 1061-1069 (2011)

  • F. Kurth, S. Bélard, A. Basra, M. Ramharter:Pyronaridine-artesunate combination therapy for the treatment of malaria.Current Opinion in Infectious Diseases 24(6): 564-569 (2011)

  • F. Kurth, S. Bélard, A. Basra, M. Ramharter:Pyronaridine: a new 'old' drug on the verge of entering the antimalarial armamentarium.Expert Review of anti-Infectious Therapy 9(4): 393-396 (2011)

  • D. Lenz, P.G. Kremsner, B. Lell, B. Biallas, M. Boettcher, B. Mordmuller, A.A. Adegnika: Assessment of LED fluorescence microscopy for the diagnosis of Plasmodium falciparum infections in Gabon. Malaria Journal 10(1): 194 (2011)

  • P. Zanger, D. Nurjadi, B. Vath, P.G. Kremsner: Persistent nasal carriage of Staphylococcus aureus is associated with deficient induction of human beta-defensin 3 after sterile wounding of healthy skin in vivo. Infection and Immunity 79(7): 2658-2562 (2011)

  • Y. Lubell, S.G. Staedke, B.M. Greenwood, M.R. Kamya, M. Molyneux, P.N. Newton, H. Reyburn, R.W.Snow, U. D'Alessandro, M. English, N. Day, P. Kremsner, A. Dondorp, W. Mbacham, G. Dorsey, S. Owusu-Agyei, K. Maitland, S. Krishna, C. Newton, G. Pasvol, T. Taylor, L. von Seidlein, N.J. White, F. Binka, A. Mills, C.J. Whitty: Likely health outcomes for untreated acute febrile illness in the tropics in decision and economic models; a Delphi survey. PLoS One 6(2): e17439 (2011)

  • malERA Consultative Group on Drugs (P.L. Alonso, A. Djimde, P. Kremsner, A. Magill, J. Milman, J. Nájera, C.V. Plowe, R. Rabinovich, T. Wells, S. Yeung S): A research agenda for malaria eradication: drugs. PLoS Medicine 8(1): e1000402. Review (2011)

  • P.I. Mayengue, M. Ndounga, F.V. Malonga, M. Bitemo, F. Ntoumi:Genetic polymorphism of merozoite surface protein-1 and merozoite surface protein-2 in Plasmodium falciparum isolates from Brazzaville, Republic of Congo.Malaria Journal 10: 276 (2011)

  • W.G. Metzger, S. Vivas-Martínez, A. Giron, E. Vaccari, E. Campos, I. Rodríguez, E. Miranda, E. Terán, L. Olivo, M. Magris:Assessment of routine malaria diagnosis in the Venezuelan Amazon.Transactions of the Royal Society of Tropical Medicine and Hygiene 105(5): 262-268 (2011)

  • L. Meurs, L. Labuda, A.S. Amoah, M. Mbow, U.A. Ngoa, D.A.Boakye, S. Mboup, T.N. Dièye, A.P. Mountford, J.D.Turner, P.G. Kremsner, K. Polman, M. Yazdanbakhsh, A.A. Adegnika:Enhanced Pro-Inflammatory Cytokine Responses following Toll-Like-Receptor Ligation in Schistosoma haematobium-Infected Schoolchildren from Rural Gabon. PLoS One 6(9): e24393 (2011)

  • L. Michelet, A. Fleury, E. Sciutto, E. Kendjo, G. Fragoso, L. Paris, B. Bouteille:Human neurocysticercosis: comparison of different diagnostic tests using cerebrospinal fluid.Journal of Clinical Microbiology 49(1): 195-200 (2011)

  • G. Mombo-Ngoma, S. Oyakhirome, R. Ord, J. Gabor, K.C. Greutélaers, K. Profanter B. Greutélaers, F. Kurth, B. Lell, J.F. Kun, S. Issifou, C.P. Roper, P.G. Kremsner, M.P. Grobusch:High prevalence of dhfr triple mutant and correlation with high rates of sulphadoxine-pyrimethamine treatment failures in vivo in Gabonese children.Malaria Journal 10: 123 (2011)

  • G. Mombo-Ngoma, C. Supan, M.P. Dal-Bianco, M.A. Missinou, P.B. Matsiegui, C.L. Ospina SalazarL, S. Issifou, D. Ter-Minassian, M. Ramharter, M. Kombila, P.G. Kremsner, B. Lell: Phase I randomized dose-ascending placebo-controlled trials of ferroquine--a candidate anti-malarial drug--in adults with asymptomatic Plasmodium falciparum infection. Malaria Journal 10: 53 (2011)

  • J. Nemeth, H.M. Winkler, L. Boeck, A.A. Adegnika, E. Clement, T.M. Mve, P.G. Kremsner, S. WinklerS: Specific cytokine patterns of pulmonary tuberculosis in Central Africa. Clinical Immunology 138(1): 50-59 (2011)

  • F. Ntoumi:The ant who learned to be an elephant. LetterScience 333(6051): 1824-1825 (2011)

  • S. Nuber, E. Petrasch-Parwez, O. Arias-Carriòn, L. Koch, Z. Kohl, J. Schneider, C. Calaminus, R. Dermietzel, A. Samarina, J. Boy, P. Teismann, H.P. Nguyen, Velavan TP, P. P.J.Kahle, S. von Hörsten, M. Fendt, R. Krüger, O. Riess:Olfactory neuron-specific expression of A30P alpha-synuclein exacerbates dopamine deficiency and hyperactivity in a novel conditional model of early Parkinson's disease stages. Neurobiology of Disease 44(2): 192-204 (2011)

  • O. Ojurongbe, A.F. Fagbenro-Beyioku, O. A. Adeyeba, J.F. Kun:Allelic diversity of merozoite surface protein 2 gene of P falciparum among children in Osogbo, Nigeria.West Indian Medical Journal 60(1): 19-23 (2011)

  • O.O. Opaleye, A.H. Fagbami, A. Lalremruata, J.F. Kun:Prevalence and association of human parvovirus B19V with hepatitis B and C viruses in Nigeria.Journal of Medical Virology 83(4): 710-716 (2011)

  • M.W. Pletz, P. Zanger, W. Jilg, W.V. Kern:Impfungen.Deutsche Medizinische Wochenschrift 136 (40): 2011-2015 (2011)

  • P. Pongratz, F. Kurth, G.M. Ngoma, A. Basra, M. Ramharter:In vitro activity of antifungal drugs against Plasmodium falciparum field isolates.Wiener Klinische Wochenschrift 123 Suppl 1: 26-30 (2011)

  • I. Rupp, L. Sologub, K.C. Williamson, M. Scheuermayer, L. Reininger, C. Doerig, S.Eksi, D.U. Kombila, M. Frank, G. Pradel:Malaria parasites form filamentous cell-to-cell connections during reproduction in the mosquito midgut.Cell Research 21(4): 683-696 (2011)

  • F. Schaumburg, R. Köck, A.W. Friedrich, S. Soulanoudjingar, U.A. Ngoa, C. von Eiff, S. Issifou, P.G. Kremsner, M. Herrmann, G. Peters, K. Becker: Population structure of Staphylococcus aureus from remote African Babongo Pygmies. PLoS Neglected Tropical Diseases 5(5): e1150 (2011)

  • F. Schaumburg, U.A. Ngoa, K. Kösters, R. Köck, A.A. Adegnika, P.G. Kremsner, B. Lell, G. Peters, A. Mellmann, K. Becker:Virulence factors and genotypes of Staphylococcus aureus from infection and carriage in Gabon.Clinical Microbiology and Infection 17(10): 1507-1513 (2011)

  • J. Schwille-Kiuntke, J.S. Frick, P. Zanger, P. Enck:Post-infectious irritable bowel syndrome--a review of the literature.Zeitschrift für Gastroenterologie 49(8): 997-1003 (2011)

  • E. Sicuri, P. Biao, G. Hutton, F. Tediosi, C. B. Menendez, B. Lell, P. Kremsner, L. Conteh, M.P. Grobusch:Cost-effectiveness of intermittent preventive treatment of malaria in infants (IPTi) for averting anaemia in Gabon: a comparison between intention to treat and according to protocol analyses.Malaria Journal 10(1): 305 (2011)

  • C. Swysen, J. Vekemans, M. Bruls, S. Oyakhirome, C. Drakeley, P. Kremsner, B. Greenwood, O. Ofori-Anyinam, B. Okech, T. Villafana, T. Carter, B. Savarese, A. Duse, A. Reijman, C. Ingram, J Frean, B. Ogutu: Development of standardized laboratory methods and quality processes for a phase III study of the RTS,S/AS01 candidate malaria vaccine. Malaria Journal 10(1): 223 (2011)

  • H.V. Tong , N.L. Toan, L.H. Song, E. A. Ouf, C.T. Bock, P.G. Kremsner, J.F. Kun, Velavan TP:Ficolin-2 Levels and FCN2 Haplotypes Influence Hepatitis B Infection Outcome in Vietnamese Patients.PLoS One 6(11): e28113 (2011)

  • S. Tschan, B. Mordmüller, J.F. Kun:Threonine peptidases as drug targets against malaria.Expert Opinion on Therapeutic Targets 15(4): 365-378 Review (2011)

  • Velavan TP, S. Bechlars, J. Tomiuk, P.G. Kremsner, J.F. Kun: Molecular characterization of regulatory polymorphisms in the promoter region of the STAT6 gene in a Gabonese population. Memórias do Instituto Oswaldo Cruz 106(1): 65-69 (2011)

  • Velavan TP, S. Bechlars, X. Huang, PG Kremsner, JFJ Kun:Novel regulatory SNPs in the promoter region of TNFRSF8 gene in a Gabonese population. Brazilian Journal of Medical and Biological Research 44(5): 418-420 (2011)

  • Velavan TP, O. Ojurongbe: Review: Regulatory T cells and Parasites. Journal of Biomedicine and Biotechnology ID 520940: 1-8 (2011)

  • K. Wahlers, C.N. Menezes, M. Wong, B. Mogoye, J. Frean, T. Romig, P. Kern, M.P. Grobusch:Human cystic echinococcosis in South Africa.Acta Tropica 120(3): 179-184 (2011)

  • P. Zanger, I. Kötter, A. Raible, T. Gelanew, G. Schönian, P.G. Kremsner: Case report: Successful treatment of cutaneous leishmaniasis caused by Leishmania aethiopica with liposomal amphothericin B in an immunocompromised traveler returning from Eritrea. American Journal of Tropical Medicine and Hygiene 84(5): 692-694 (2011)

Zertifikate und Verbände

Focus: Top Nationales Krankenhaus 2024

Die deutschen Universitätsklinika

Kooperation für Transparenz und Qualität im Gesundheitswesen

Qualitätspartnerschaft mit der PKV

Blauer Sterne Betrieb

Erfolgsfaktor Familie

Die Altersvorsorge für den Öffentlichen Dienst

Springe zum Hauptteil
Internationale Patienten Presse