Medizinische Klinik
Innere Medizin VII
Institut für Tropenmedizin, Reisemedizin, Humanparasitologie

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Adresse: Wilhelmstraße 27
72074 Tübingen

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Publikationen 2012

  • A. Adegnika, P.G. P.G. Kremsner:Epidemiology of malaria and helminth interaction: a review from 2001 to 2011.Current Opinion in HIV and AIDS 7(3): 221-4 (2012)

  • S.T. Agnandji, V. Tsassa, C. Conzelmann, C Köhler, H.J. Ehni:Patterns of biomedical science production in a sub-Saharan research center.BMC Medical Ethics 13:3 (2012)

  • IF: 1,737A. Ajua, T. Engleitner, M. Esen, M. Theisen, S. Issifou, B. Mordmüller:A flow cytometry-based workflow for detection and quantification of anti-plasmodial antibodies in vaccinated and naturally exposed individuals.Malaria Journal 11(1): 367 (2012)

  • A. Assaf, T.V. Hoang, I. Faik, T. Aebischer, P.G. Kremsner, J.F.Kun, T.P.Velavan:Genetic evidence of functional ficolin-2 haplotype as susceptibility factor in cutaneous leishmaniasis.PLoS One 7(3): e34113 (2012)

  • L. Auer-Hackenberg, T. Staudinger, A. Bojic, G. Locker, G.C. Leitner, W. Graninger, S. Winkler, M. Ramharter, N. Worel:Automated red blood cell exchange as an adjunctive treatment for severe Plasmodium falciparum malaria at the Vienna General Hospital in Austria: a retrospective cohort study.Malaria Journal 11: 158 (2012)

  • L. Auer-Hackenberg, S. Winkler, W. Graninger, N. Worel, M. Ramharter M:Current evidence and future of automated erythrocyte exchange in the treatment of severe malaria.Wiener Klinische Wochenschrift 124 Suppl 3: 23-26 (2012)

  • A. Baumann, M.M. Magris, M.L. Urbaez, S. Vivas-Martinez, R. Durán, T. Nieves, M. Esen, B.G. Mordmüller, M. Theisen, L. Avilan, W.G. Metzger:Naturally acquired immune responses to malaria vaccine candidate antigens MSP3 and GLURP in Guahibo and Piaroa indigenous communities of the Venezuelan Amazon.Malaria Journal 11: 46(2012)

  • E. Böttger, G. Multhoff, J.F. Kun, M. Esen:Plasmodium falciparum-infected erythrocytes induce granzyme B by NK cells through expression of host-Hsp70.PLoS One 7(3): e33774 (2012)

  • O. Bouchaud, N. Mühlberger, P. Parola, G. Calleri, A. Matteelli, G. Peyerl-Hoffmann F. Méchaï, P. Gautret, J. Clerinx, P.G. Kremsner, T. Jelinek, A. Kaiser, A. Beltrame M.L. Schmid, P. Kern, M. Probst, A. Bartoloni, T. Weinke, M.P. Grobusch MP:Therapy of uncomplicated falciparum malaria in Europe: MALTHER - a prospective observational multicentre study.Malaria Journal 11: 212 (2012)

  • T. Bouchery, K. Ehrhardt, E. Lefoulon, W. Hoffmann, O. Bain, C. Martin:Differential tissular distribution of Litomosoides sigmodontis microfilariae between microfilaremic and amicrofilaremic mice following experimental infection.Parasite 19(4): 351-358 (2012)

  • F.J. Breeveld, S.G. Vreden, M.P. Grobusch:History of malaria research and its contribution to the malaria control success in Suriname: a review.Malaria Journal 11: 95 (2012)

  • K. Brücher, B. Illarionov, J. Held, S. Tschan, A. Kunfermann, M.K. Pein, A. Bacher, T. Gräwert, L. Maes, B. Mordmüller, M. Fischer, T. Kurz:?-Substituted ?-oxa isosteres of fosmidomycin: synthesis and biological evaluation.Journal of Medicinal Chemistry 55(14): 6566-6575 (2012)

  • M. Capan, G. Mombo-Ngoma, D. Akerey-Diop, A. Basra, H. Würbel, W. Lendamba, L. Auer- Hackenberg, R. Mackanga, J. Melser, S. Belard, M. Ramharter M:Epidemiology and management of group B streptococcal colonization during pregnancy in Africa.Wiener Klinische Wochenschrift 124 Suppl 3: 14-16 (2012)

  • J. Ehrhardt, K. Tintelnot, P. Kremsner, M. Frank:[Progressive malaise and joint pain after travel to Costa Rica].Deutsche Medizinische Wochenschrift 137(44): 2260 (2012)

  • M. Esen, J. Forster, A. Ajua, I. Spänkuch, M. Paparoupa, B. Mordmüller, P.G. P.G. Kremsner:JEffect of IL-15 on IgG versus IgE antibody-secreting cells in vitro.Journal of Immunological Methods 375(1-2): 7-13 (2012)

  • M. Esen, B. Mordmüller, P.M. de Salazar, A.A. Adegnika, S.T. Agnandji, F. Schaumburg, A.B. Hounkpatin, S. Brückner, M. Theisen, S. Bélard, U.A. Ngoa, S. Issifou, M. Yazdanbakhsh, P.G. Kremsner:Reduced antibody responses against Plasmodium falciparum vaccine candidate antigens in the presence of Trichuris trichiura.Vaccine 30(52) :7621-7624 (2012)

  • S. Gabrysch, P. Zanger, O.M. Campbell:Emergency obstetric care availability: a critical assessment of the current indicator.Tropical Medicine and International Health 17(1): 2-8 (2012)

  • A.A. Hogewoning, J.N. Bouwes Bavinck, A.S. Amoah, D.A. Boakye, M. Yazdanbakhsh, P.G. Kremsner, A.A. Adegnika, S.K. De Smedt, R. Willemze, A.P. Lavrijsen:Point and period prevalences of eczema in rural and urban schoolchildren in Ghana, Gabon and Rwanda.Journal of the European Academy of Dermatology and Venereology 26(4): 488-494 (2012)

  • X. Huang, V. Kühne, J.F. Kun, P.T. Soboslay, B. Lell B, T.P. Velavan:In-vitro characterization of novel and functional regulatory SNPs in the promoter region of IL2 and IL2R alpha in a Gabonese population.BMC Medical Genetics (1): 117 (2012)

  • R. Ibara-Okabande, F. Koukouikila-Koussounda, M. Ndounga, J. Vouvoungui, V. Malonga, P.N. Casimiro, J.R.Ibara, A. Sidibe, F. Ntoumi:Reduction of Multiplicity of infections but no change in msp2 genetic diversity in P. falciparum isolates from Congolese children after introduction of artemisin-combination therapies. Malaria Journal 11: 410 (2012)

  • Z.M. Idris, M. Yazdanbakhsh, A.A. Adegnika, B. Lell, S. Issifou, R. Noordin:A pilot study on cytotoxic T lymphocyte-4 gene polymorphisms in urinary schistosomiasis.Genetic Testing and Molecular Biomarkers 16(6): 488-492 (2012)

  • E. Ivan, N.J. Crowther, A.T. Rucogoza, L.O. Osuwat, E. Munyazesa, E. Mutimura, K.J. Njunwa, K.J. Zambezi, M.P. Grobusch:Malaria and helminthic co-infection among HIV-positive pregnant women: Prevalence and effects of antiretroviral therapy.Acta Tropica 124(3): 179-184 (2012)

  • S. Janssen, R. Jayachandran, L. Khathi, J. Zinsstag, M.P. Grobusch, J. Pieters:Exploring prospects of novel drugs for tuberculosis.Drug Design, Development and Therapy 6: 217-224 (2012)

  • M.P.G. Jepsen, D. Röser, M. Christiansen, S. Olesen Larsen, D.R. Cavanagh, K. Dhanasarnsombut, I. Bygbjerg, D. Dodoo, E.J. Remarque, M. Dziegiel, S. Jepsen, B. Mordmüller, M. Theisen:Development and evaluation of a multiplex screening assay for Plasmodium falciparum exposure.Journal of Immunological Methods 384(1-2): 62-70 (2012)

  • A.N. Jha, V.K. Singh, N. Kumari, A. Singh, J. Antony, H. van Tong, S. Singh, S.S. Pati, P.K. Patra, R. Singh, N.L. Toan, le H. Song, A. Assaf, I.J. Messias-Reason, T.P. Velavan, L. Singh, K. Thangaraj:IL-4 haplotype -590T, -34T and intron-3 VNTR R2 is associated with reduced malaria risk among ancestral indian tribal populations.PLoS One 7(10): e48136 (2012)

  • F. Joanny, J. Held, B. Mordmüller B:In Vitro Activity of Fluorescent Dyes against Asexual Blood Stages of Plasmodium falciparum.Antimicrobial Agents and Chemotherapy 56(11): 5982-5985 (2012)

  • K. Kayentao, O.K. Doumbo, L.K. Pénali, A.T. Offianan, K.M. Bhatt, J. Kimani, A.K. Tshefu, J.H. Kokolomami, M. Ramharter, P.M. de Salazar, A.B. Tiono, A. Ouédraogo, M.D. Bustos, F. Quicho, I. Borghini-Fuhrer, S. Duparc, C.S. Shin, L. Fleckenstein:Pyronaridine-artesunate granules versus artemether-lumefantrine crushed tablets in children with Plasmodium falciparum malaria: a randomized controlled trial.Malaria Journal 11: 364 (2012)

  • N. Kapata, P. Chanda-Kapata, M.P. Grobusch, J. O'Grady, S. Schwank, M. Bates, S. Jansenn, A. Mwinga, F. Cobelens, P. Mwaba, A. Zumla:Scale-up of TB and HIV programme collaborative activities in Zambia - a 10-year review.Tropical Medicine and International Health 17(6): 760-766 (2012)

  • F. Koukouikila-Koussounda, V. Malonga, P.I. Mayengue, M. Ndounga, C.J. Vouvoungui, F. Ntoumi:Genetic polymorphism of merozoite surface protein 2 and prevalence of K76T pfcrt mutation in Plasmodium falciparum field isolates from Congolese children with asymptomatic infections.Malaria Journal 11:105 (2012)

  • P.G. Kremsner, T. Taylor, S. Issifou, M. Kombila, Y. Chimalizeni, K. Kawaza, M.K. Bouyou Akotet, M. Duscha, B. Mordmüller, K. Kösters, A. Humberg, R.S. Miller, P. Weina, S. Duparc, J. Möhrle, J.F. Kun, T. Planche, P. Teja-Isavadharm, J.A. Simpson, C. Köhler, S. Krishna:A simplified intravenous artesunate regimen for severe malaria.Journal of Infectious Diseases 205(2): 312-319 (2012)

  • H. Lagler, K. Grabmeier-Pfistershammer, V. Touzeau-Römer, S. Tobudic, M. Ramharter, J. Wenisch, G.A. Gualdoni, M. Redlberger-Fritz, T. Popow-Kraupp, A. Rieger, H. Burgmann:Immunogenicity and tolerability after two doses of non-adjuvanted, whole-virion pandemic influenza A (H1N1) vaccine in HIV-infected individuals.PLoS One 7(5): e36773 (2012)

  • H. Lagler, S. Tobudic, M. Ramharter, K. Elandt, W.R. Sperr, M. Redlberger-Fritz, T. Popow-Kraupp, U. Jäger, C.C. Zielinski, H. Burgmann:Pandemic whole-virion, Vero-cell-derived, adjuvant-free influenza A H1N1 vaccine in patients with solid tumors and hematologic malignancies receiving concurrent anticancer treatment: Immunogenicity, tolerability, and acceptability during the pandemic situation.Vaccine 30(48): 6864-6870 (2012)

  • M. Lanaspa, C. Moraleda, S. Machevo, R. González, B. Serrano, E. Macete, P. Cisteró, A. Mayor, D. Hutchinson, P.G. Kremsner, P. Alonso, C. Menéndez, Q. Bassat:Inadequate efficacy of a new formulation of fosmidomycin-clindamycin combination in Mozambican children less than three years old with uncomplicated Plasmodium falciparum malaria.Antimicrobial Agents and Chemotherapy 56 (6):2923-2928 (2012)

  • C.J. Lechner, R.G. Gantin, T. Seeger, A. Sarnecka, J. Portillo, H. Schulz-Key, P.K. Karabou, G. Helling-Giese, C. Heuschkel, M. Banla, P.T. Soboslay:Chemokines and cytokines in patients with an occult Onchocerca volvulus infection.Microbes and Infection 14(5): 438-446 (2012)

  • C.J. Lechner, B. Grüner, X. Huang, W.H. Hoffmann, P. Kern, P.T. Soboslay:Parasite-specific IL-17-type cytokine responses and soluble IL-17 receptor levels in Alveolar Echinococcosis patients.Clinical and Developmental Immunology 2012: 735342 (2012)

  • G. Mombo-Ngoma, C. Kleine, A. Basra, H. Würbel, D.A. Diop, M. Capan, A.A. Adegnika, F. Kurth, B. Mordmüller, F. Joanny, P.G. Kremsner, M. Ramharter, S. Bélard:Prospective evaluation of artemether-lumefantrine for the treatment of non-falciparum and mixed-species malaria in Gabon.Malaria Journal 11: 120 (2012)

  • U.A. Ngoa, G.K. Adzoda, B.M. Louis, A.A. Adegnika, B. Lell:Buruli ulcer in Gabon, 2001-2010.Emerging Infectious Diseases 18(7): 1206-1207 (2012)

  • U.A. Ngoa, F. Schaumburg, A.A. Adegnika, K. Kösters, T. Möller, J.F. Fernandes A. Alabi, S. Issifou, K. Becker, M.P. Grobusch, P.G. Kremsner, B. Lell:Epidemiology and population structure of Staphylococcus aureus in various population groups from a rural and semi urban area in Gabon, Central Africa.Acta Tropica 124(1): 42-47 (2012)

  • D. Nurjadi, J. Lependu, P.G. Kremsner, P. Zanger:Staphylococcus aureus throat carriage is associated with ABO-/secretor status.Journal of Infection 65(4): 310-317 (2012)

  • O. Ojurongbe, E.A. Ouf, H. Van Tong, N.L. Toan, le H. Song, P.R. Luz, I.J. Messias-Reason, D. Nurjadi, P. Zanger, J.F. Kun, P.G. Kremsner, T.P.Velavan:Reliable and rapid characterization of functional FCN2 gene variants reveals diverse geographical patterns.BMC Medical Genetics 13: 37 (2012)

  • A.O. Olalekan, F. Schaumburg, D. Nurjadi, A.E. Dike, O. Ojurongbe, D.O. Kolawole, J.F. Kun, P. Zanger:Clonal expansion accounts for an excess of antimicrobial resistance in Staphylococcus aureus colonising HIV-positive individuals in Lagos, Nigeria.International Journal of Antimicrobial Agents 40(3): 268-272 (2012)

  • E.A. Ouf, O. Ojurongbe, A.A. Akindele, O.R. Sina-Agbaje, H. Van Tong, A.O. Adeyeba, P.G. Kremsner, J.F. Kun, T. Velavan:Ficolin-2 levels and FCN2 genetic polymorphisms as a susceptibility factor in schistosomiasis.Journal of Infectious Diseases 206(4): 562-570 (2012)

  • W.R. Prescott, R.G. Jordan, M.P. Grobusch, V.M. Chinchilli, I. Kleinschmidt, J. Borovsky, M. Plaskow, M. Torrez, M. Mico, C. Schwabe:Performance of a malaria microscopy image analysis slide reading device.Malaria Journal 11: 155 (2012)

  • F. Ratzinger, H. Bruckschwaiger, M. Wischenbart, B. Parschalk, D. Fernandez-Reyes, H. Lagler, A. Indra, W. Graninger, S. Winkler, S. Krishna, M. Ramharter:Rapid diagnostic algorithms as a screening tool for tuberculosis: an assessor blinded cross-sectional study.PLoS One 7(11): e49658 (2012)

  • RTS,S Clinical Trials Partnership, S.T. Agnandji, B. Lell, J.F. Fernandes, B.P. Abossolo, B. G. Methogo, 'A.L. Kabwende, A.A. Adegnika, B. Mordmüller, S. Issifou, P.G. Kremsner, J. Sacarlal, P. Aide, M. Lanaspa, J.J. Aponte, S. Machevo, S. Acacio, H. Bulo, B. Sigauque, E. Macete, P. Alonso, S. Abdulla, N. Salim, R. Minja, M. Mpina, S. Ahmed, A.M. Ali, A.T. Mtoro, A.S. Hamad, P. Mutani, M. Tanner, H. Tinto, U. D'Alessandro, H. Sorgho, I. Valea, B. Bihoun, I. Guiraud, B. Kaboré, O. Sombié, R.T. Guiguemdé, J.B. Ouédraogo, M.J. Hamel, S. Kariuki, M. Oneko, C. Odero, K. Otieno, N. Awino, M. McMorrow, V. Muturi-Kioi, K.F. Laserson, L. Slutsker, W. Otien, L. Otieno, N. Otsyula, S. Gondi, A. Otieno, V. Owira, E. Oguk, G. Odongo, J.B. Woods, B. Ogutu, P. Njuguna, R. Chilengi, P. Akoo, C. Kerubo, C. Maingi, T. Lang, A. Olotu, P. Bejon, K. Marsh, G. Mwambingu, S. Owusu-Agyei, K.P. Asante, K. Osei-Kwakye, O. Boahen, D. Dosoo, I. Asante, G. Adjei, E. Kwara, D. Chandramohan, B. Greenwood, J. Lusingu, S. Gesase, A. Malabeja, O. Abdul, C. Mahende, E. Liheluka, L. Malle, M. Lemnge, T.G. Theander, C. Drakeley, D. Ansong, T. Agbenyega,S. Adjei, H.O. Boateng, T. Rettig, J. Bawa, J. Sylverken, D. Sambian, A. Sarfo, A. Agyekum, F. Martinson, I. Hoffman, T. Mvalo, P. Kamthunzi, R. Nkomo, T. Tembo, G. Tegha, M. Tsidya, J. Kilembe, C. Chawinga, W.R. Ballou, J. Cohen, Y. Guerra, E. Jongert, D. Lapierre, A. Leach, M. Lievens, O. Ofori-Anyinam, A. Olivier, J. Vekemans, T. Carter, D. Kaslow, D. Leboulleux, C. Loucq, A. Radford, B. Savarese, D. Schellenberg, M. Sillman, P. Vansadia:A phase 3 trial of RTS,S/AS01 malaria vaccine in African infants.New England Journal of Medicine 367(24): 2284-2295 (2012)

  • M.H. Selman, S.E. de Jong, D. Soonawala, F.P. Kroon, A.A. Adegnika, A.M. Deelder, C.H. Hokke, M. Yazdanbakhsh, M. Wuhrer:Changes in antigen-specific IgG1 Fc N-glycosylation upon influenza and tetanus vaccination.Molecular and Cellular Proteomics 11(4): M111.014563 (2012)

  • N. Sessler, K. Krug, A. Nordheim, B. Mordmüller, B. Macek:Analysis of the Plasmodium falciparum proteasome using Blue Native PAGE and label-free quantitative mass spectrometry.Amino Acids: 43(3): 1119-1129 (2012)

  • L.S. Seydel, A. Petelski, G.J. van Dam, D. van der Kleij, Y.C. Kruize-Hoeksma, A. J. Luty, M. Yazdanbakhsh, P.G. Kremsner:Association of in utero sensitization to Schistosoma haematobium with enhanced cord blood IgE and increased frequencies of CD5- B cells in African newborns.American Journal of Tropical Medicine and Hygiene 86(4): 613-619 (2012)

  • C. Supan, G. Mombo-Ngoma, M.P. Dal-Bianco, C.L. Ospina Salazar, S. Issifou, F. Mazuir, A. Filali-Ansary, C. Biot, D. Ter-Minassian, M. Ramharter, P.G. Kremsner, B. Lell:Pharmacokinetics of ferroquine, a novel 4-aminoquinoline, in asymptomatic carriers of Plasmodium falciparum infections.Antimicrobial Agents and Chemotherapy 56(6): 3165-3173 (2012)

  • H.V. Tong, N.L. Toan, le H. Song le, P.G. Kremsner, J.F. Kun, T.P.Velavan:Association of CISH -292A/T genetic variant with hepatitis B virus infection.Immunogenetics: 64(4): 261-265 (2012)

  • S. Tschan, P.G. Kremsner, B. Mordmüller:Emerging drugs for malaria.Expert Opinion on Emerging Drugs: 17(3): 319-333 (2012)

  • L. E. van der Vlugt, L.A. Labuda LA, A. Ozir-Fazalalikhan, E. Lievers, A.K. Gloudemans, K.Y. Liu, T.A. Barr, T. Sparwasser, L. Boon, U.A. Ngoa, E.N. Feugap, A.A. Adegnika, P.G. Kremsner, D. Gray, M. Yazdanbakhsh, H.H. Smits:Schistosomes induce regulatory features in human and mouse CD1d(hi) B cells: inhibition of allergic inflammation by IL-10 and regulatory T cells.PLoS One 7(2): 30883 (2012)

  • T.P. Velavan, B. Büyükyazici, P.G. Kremsner, J.F. Kun:Combined promoter haplotypes of the IL10R genes are associated with protection against severe malaria in Gabonese children.Immunogenetics 64(2): 87-95 (2012)

  • K. Wahlers, C.N. Menezes, M.L. WongL, E. Zeyhle, M.E. Ahmed, M. Ocaido, C. Stijnis, T. Romig, P. Kern, M.P. Grobusch:Cystic echinococcosis in sub-Saharan Africa.Lancet Infectious Diseases 2012 Nov;12(11):871-80(2012)

  • R.W. Wieten, T. Leenstra, A. Goorhuis, M. van Vugt, M.P. Grobusch:Health risks of travelers with medical conditions--a retrospective analysis.Journal of Travel Medicine 19(2): 104-110 (2012)

  • IF: 1,748R.W. Wieten, W. Vlietstra, A. Goorhuis, M. van Vugt, C.J. Hodiamont, T. Leenstra. P.J. de Vries, S. Janssen, P.P. van Thiel, K. Stijnis, M.P. Grobusch MP:Dengue in travellers: applicability of the 1975-1997 and the 2009 WHO classification system of dengue fever.Tropical Medicine and International Health 17(8): 1023-1030 (2012)

  • P. Zanger, D. Nurjadi, R. Schleucher, H. Scherbaum, C. Wolz, P.G. Kremsner, B. Schulte:Import and spread of Panton-Valentine Leukocidin-positive Staphylococcus aureus through nasal carriage and skin infections in travelers returning from the tropics and subtropics.Clinical Infectious Diseases 54(4): 483-492 (2012)

  • P. Zanger, D. Nurjadi, M. Gaile, S. Gabrysch S, P.G. Kremsner:Hormonal Contraceptive Use and Persistent Staphylococcus aureus Nasal Carriage.Clinical Infectious Diseases 55(12): 1625-1632 (2012)

  • P. Zanger, I. Kötter, P.G. Kremsner, S. Gabrysch:Tumor necrosis factor alpha antagonist drugs and leishmaniasis in Europe.Clinical Microbiology and Infection 18(7): 670-676 (2012)

  • S. Ziewer, M.P. Hübner, B. Dubben, W.H. Hoffmann, O. Bain, C.Martin, A. Hoerauf, S.

  • Specht:Immunization with L. sigmodontis microfilariae reduces peripheral microfilaraemia after challenge infection by inhibition of filarial embryogenesis.PLoS Neglected Tropical Diseases 6(3): e1558 (2012) 

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Die deutschen Universitätsklinika

Kooperation für Transparenz und Qualität im Gesundheitswesen

Qualitätspartnerschaft mit der PKV

Blauer Sterne Betrieb

Erfolgsfaktor Familie

Die Altersvorsorge für den Öffentlichen Dienst

Springe zum Hauptteil
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