Medizinische Klinik
Innere Medizin VII
Institut für Tropenmedizin, Reisemedizin, Humanparasitologie

811

Adresse: Wilhelmstraße 27
72074 Tübingen


Publikationen 2013

  • A.S. Alabi, L. Frielinghaus, H. Kaba, K. Kösters, M.A. Huson, B.C. Kahl, G. Peters, M.P. Grobusch, S. Issifou, P.G. Kremsner, F. Schaumburg: Retrospective analysis of antimicrobial resistance and bacterial spectrum of infection in Gabon, Central Africa. BMC Infectious Diseases 13(1): 455 (2013)

  • J.S. Antony, O. Ojurongbe, H. van Tong, E.A. Ouf, T. Engleitner, A.A. Akindele, O.R. Sina-Agbaje, A.O. Adeyeba, P.G. Kremsner, T.P.Velavan: Mannose binding lectin and susceptibility to Schistosomiasis. Journal of Infectious Diseases 207(11): 1675-1683 (2013)

  • M. Banla, N. Maneh, B. Vonor, K.B. Nonon Saa, A. Agba, R.G. Gantin, K.P. Balo, P.T. Soboslay, B. Bakondé: [Tropical endemic limbo-conjunctivitis (TELC) and allergic management: a preliminary study in Togolese children]. Journal Français D'Ophtalmologie 36(8): 677-82 (2013)

  • A. Basra, G. Mombo-Ngoma, M. Capan Melser, D. Akerey Diop, H. Würbel, J.R. Mackanga, M. Fürstenau, R. Manego Zoleko, A.A. Adegnika, R. Gonzalez, C. Menendez, P.G. Kremsner, M. Ramharter: Efficacy of Mefloquine Intermittent Preventive Treatment in Pregnancy Against Schistosoma haematobium Infection in Gabon: A Nested Randomized Controlled Assessor-Blinded Clinical Trial. Clinical Infectious Diseases 56(6): e68-e75 (2013)

  • P. Bejon, M.T. White, A. Olotu, K. Bojang, J.P. Lusingu, N. Salim, N.N. Otsyula, S.T. Agnandji, K.P. Asante, S. Owusu-Agyei, S. Abdulla, A.C. Ghani: Efficacy of RTS,S malaria vaccines: individual-participant pooled analysis of phase 2 data. Lancet Infectious Diseases 13(4): 319-327 (2013)

  • E. Böttger, E. Grangeiro de Carvalho, S. Meese, J.F. Kun, M. Esen: Expression of Interleukin-6 Family Receptors in NK92 Cells Is Regulated by Cytokines and Not Through Direct Interaction with Plasmodium falciparum-Infected Erythrocytes. Journal of Interferon & Cytokine Research 33(2): 65-71 (2013)

  • A.B. Boldt, M.I. Sanchez, E.R. Stahlke, R. Steffensen, S. Thiel, J.C. Jensenius, F.C. Prevedello, M.T. Mira, J.F. Kun, I.J. Messias-Reason: Susceptibility to leprosy is associated with M-ficolin polymorphisms. Journal of Clinical Immunology 33(1): 210-219 (2013)

  • A. Clark, F. Gerlach, Hv Tong, N.X. Hoan, H. Song le, N.L. Toan, C.T. Bock, P.G. Kremsner, T.P. Velavan: A trivial role of STAT4 variant in chronic hepatitis B induced hepatocellular carcinoma. Infection, Genetics and Evolution 18: 257-261 (2013)

  • J. Ehrhardt, A. Trein A, P.G.Kremsner, M. Frank: Plasmodium knowlesi and HIV co-infection in a German traveller to Thailand. Malaria Journal 12(1): 283 (2013)

  • I.Goeldner, T.L. Skare, S.R. Utiyama, R.M. Nisihara, H.v. Tong, I.J. Messias-Reason, T.P. Velavan: Mannose binding lectin and susceptibility to rheumatoid arthritis in brazilian patients and their relatives. PLoS One 21;9(4):e95519 (2014)

  • O. Goovaerts, W. Jennes, M. Massinga-Loembé, A. Ceulemans, W. Worodria, H. Mayanja-Kizza, R. Colebunders, L. Kestens, TB-IRIS Study Group: LPS-Binding Protein and IL-6 Mark Paradoxical Tuberculosis Immune Reconstitution Inflammatory Syndrome in HIV Patients. PLoS One 8(11): e81856 (2013)

  • J. Held, A. Kreidenweiss, B. Mordmüller: Novel approaches in antimalarial drug discovery. Expert Opinion on Drug Discovery 8(11): 1325-1337 (2013)

  • M. Herrmann, S. Abdullah, A. Alabi, P. Alonso, A.W. Friedrich, G. Fuhr, A. Germann, W.V. Kern, P.G. Kremsner, I. Mandomando, A.C. Mellmann, G. Pluschke, S. Rieg, U. Ruffing, F. Schaumburg, M. Tanner, G. Peters, H. von Briesen, C. von Eiff, L. von Müller, M.P. Grobusch: Staphylococcal disease in Africa: another neglected 'tropical' disease. Future Microbiology 8: 17-26 (2013)

  • A. Hogewoning, A. Amoah, J.N. Bavinck, D. Boakye, M. Yazdanbakhsh, A. Adegnika, S. De Smedt, Y. Fonteyne, R. Willemze, A. Lavrijsen: Skin diseases among schoolchildren in Ghana, Gabon, and Rwanda. International Journal of Dermatology 52(5): 589-600 (2013)

  • E. Ivan, N.J. Crowther, E. Mutimura, L.O. OsuwatO, S. Janssen, M.P. Grobusch: Helminthic infections rates and malaria in HIV-infected pregnant women on anti-retroviral therapy in Rwanda. PLoS Neglected Tropical Diseases 7(8): e2380 (2013)

  • M.J. Jäckle, C.G. Blumentrath, R.M. Zoleko, D. Akerey-Diop, J.R. Mackanga, A.A. Adegnika, B. Lell, P.B. Matsiegui, P.G. Kremsner, G. Mombo-Ngoma, M. Ramharter: Malaria in pregnancy in rural Gabon: a cross-sectional survey on the impact of seasonality in high-risk groups. Malaria Journal 12(1): 412 (2013)

  • S. Janssen, X. Padanilam, R. Louw, R. Mahanyele, G. Coetzee, T. Hänscheid, T. Leenstra, M.P. Grobusch: How many sputum culture results do we need to monitor multidrug-resistant-tuberculosis (MDR-TB) patients during treatment? Journal of Clinical Microbiology 51(2): 644-646 (2013)

  • M.P. Jepsen, P.S. Jogdand, S.K. Singh, M. Esen, M. Christiansen, S. Issifou, A.B. HounkpatinB, U. Ateba-Ngoa, P.G. Kremsner, M.H. Dziegiel, S. Olesen-Larsen, S. Jepsen, B. Mordmüller, M. Theisen: The Malaria Vaccine Candidate GMZ2 Elicits Functional Antibodies in Individuals From Malaria Endemic and Non-Endemic Areas. Journal of Infectious Diseases 208(3): 479-488 (2013)

  • L. Kamgue Sidze, E. Mouafo Tekwu, Christopher Kuaban, J.P. Assam Assam, J.C. Tedom, S. Niemann, M. Frank, V. N. Penlap Beng: Estimates of Genetic Variability of Mycobacterium tuberculosis Complex and Its Association with Drug Resistance in Cameroon. Advances in Infectious Diseases 3: 55-59 (2013)

  • N. Kapata, P. Chanda-Kapata, J. O'Grady, M. Bates, P. Mwaba, S. Janssen, B. Marais, F. Cobelens, M. Grobusch, A. Zumla: Trends in childhood tuberculosis in zambia: a situation analysis. Journal of Tropical Pediatrics 59(2): 134-139 (2013).

  • E. Kendjo, T. Agbenyega, K. Bojang, C.R. Newton, M. Bouyou-Akotet, F. Pedross, M. Kombila, R. Helbok, P.G. Kremsner: Mortality patterns and site heterogeneity of severe malaria in african children. PLoS One 8(3): e58686 (2013)

  • A. Khattab, P.G. Kremsner, S. Meri: Complement activation in primiparous women from a malaria endemic area is associated with reduced birthweight. Placenta 34(2): 162-167. (2013)

  • D. Kieninger, E. Sheldon, W.Y. Lin, C.J.Yu, J.M. Bayas, J.J. Gabor, M. Esen, J.L. Fernandez Roure, S. Narejos Perez, C. Alvarez Sanchez, Y. Feng, C. Claeys, M. Peeters, B.L. InnisL, V. Jain: Immunogenicity, reactogenicity and safety of an inactivated quadrivalent influenza vaccine candidate versus inactivated trivalent influenza vaccine: a phase III, randomized trial in adults aged >=18 years. BMC Infectious Diseases 13(1): 343 (2013)

  • D.U. Kombila, J.B. Moussavou-Kombila, M.P. Grobusch, B. Lell: Clinical and laboratory features of tuberculosis within a hospital population in Libreville, Gabon. Infection 41(3): 737-739 (2013)

  • F. Koukouikila-Koussounda, A.A. Abena, A. Nzoungani, J.V. Mombouli, J.M.Ouamba, J. Kun F. Ntoumi F: In vitro evaluation of antiplasmodial activity of extracts of Acanthospermum hispidum DC (Asteraceae) and Ficus thonningii Blume (Moraceae), two plants used in traditional medicine in the Republic of Congo. African Journal Of Traditional, Complementary and Alternative 10(2): 270-276 (2013)

  • F. Koukouikila-Koussounda, F. Ntoumi, M. Ndounga, H.V.Tong, A.A. Abena, T.P. Velavan: Genetic evidence of regulatory gene variants of the STAT6, IL10R and FOXP3 locus as a susceptibility factor in uncomplicated malaria and parasitaemia in Congolese children. Malaria Journal 12: 9 (2013)

  • A. Kreidenweiss, A.V. Hopkins, B. Mordmüller. 2A and the Auxin-Based Degron System Facilitate Control of Protein Levels in Plasmodium falciparum. PLoS One 8(11): e78661 (2013)

  • S. Krishna, P.G. Kremsner: Antidogmatic approaches to artemisinin resistance: reappraisal as treatment failure with artemisinin combination therapy. Trends in Parasitology 29(7): 313-317 (2013)

  • S. Krishna, P.G. Kremsner: Artemisinin resistance needs to be defined rigorously to be understood: response to Dondorp and Ringwald. Trends in Parasitology 29(8): 361-362 (2013)

  • A.Kunfermann, C. Lienau, B. Illarionov, J. Held, T. Gräwert, C.T. Behrendt, P. Werner, S. Hähn, W. Eisenreich, U. Riederer, B. Mordmüller, A. Bacher, M. Fischer, M. Groll, T. Kurz: IspC as Target for Antiinfective Drug Discovery: Synthesis, Enantiomeric Separation, and Structural Biology of Fosmidomycin Thia Isosters. Journal of Medicinal Chemistry 56(20): 8151-8162 (2013)

  • L.A. Labuda, U. Ateba-Ngoa U, E.N. Feugap, J.J. Heeringa, L.E. van der Vlugt, R.B. Pires, L. Mewono, P.G. Kremsner, M.C. van Zelm, A.A. Adegnika, M. Yazdanbakhsh, H.H. Smits:
    Alterations in Peripheral Blood B Cell Subsets and Dynamics of B Cell Responses during Human Schistosomiasis. PLoS Neglected Tropical Diseases 7(3): e2094 (2013)

  • A.Lalremruata, M. Ball, R. Bianucci, B. Welte, A.G. Nerlich, J.F.Kun, C.M. Pusch: Molecular identification of falciparum malaria and human tuberculosis co-infections in mummies from the Fayum depression (Lower Egypt). PLoS One 8(4): e60307 (2013)

  • C.J. Lechner, K. Komander, J. Hegewald, X. Huang, R.G. Gantin, P.T. Soboslay, A. Agossou, M. Banla, C. Köhler: Cytokine and chemokine responses to helminth and protozoan parasites and to fungus and mite allergens in neonates, children, adults, and the elderly. Immunity and Ageing 10(1): 29 (2013)

  • P.R. Luz, T.P. Velavan, P.G. Kremsner, I.J. Messias-Reason: Association of IP-10 and PDGF-BB levels with clinical forms of chronic Chagas disease. International Journal of Cardiology 169(4): e53-55 (2013)

  • P.R. Luz, A.B. Boldt, C. Grisbach, J.F. Kun, T.P. Velavan, I.J. Messias-Reason: Association of L-Ficolin Levels and FCN2 Genotypes with Chronic Chagas Disease. PLoS One 8(4): e60237 (2013)

  • H. Mamo, M. Esen, A. Ajua, M. Theisen, B. Mordmüller, B. Petros: Humoral immune response to Plasmodium falciparum vaccine candidate GMZ2 and its components in populations naturally exposed to seasonal malaria in Ethiopia. Malaria Journal 12: 1 (2013)

  • P. Marcinek, A.N. Jha, V. Shinde, A. Sundaramoorthy, R. Rajkumar, N.C. Suryadevara, S.K. Neela, H. van Tong, V. Balachander, V.L. Valluri, K. Thangaraj, T.P. Velavan: LRRK2 and RIPK2 Variants in the NOD 2-Mediated Signaling Pathway Are Associated with Susceptibility to Mycobacterium leprae in Indian Populations. PLoS One 8(8): e73103 (2013)

  • J.E. McElhaney, J. Beran, J.M. Devaster, M. Esen, O. Launay, G. Leroux-Roels, G.M. Ruiz-Palacios, G.A. van Essen, A. Caplanusi, C. Claeys, C. Durand, X. Duval, M. El Idrissi, A.R. Falsey, G. Feldman, S.E. Frey, F. Galtier, S.J. Hwang, B.L. Innis, M. Kovac, P. Kremsner, S. McNeil, A. Nowakowski, J.H. Richardus, A. Trofa, L. Oostvogels; Influence65 study group: AS03-adjuvanted versus non-adjuvanted inactivated trivalent influenza vaccine against seasonal influenza in elderly people: a phase 3 randomised trial. Lancet Infectious Diseases 13(6): 485-96 (2013)

  • G.M. Miiro, O.O. Oukem-Boyer, O. Sarr, M. Rahmani, F. Ntoumi, Dheda K, Pym A, Mboup S, Kaleebu P; NoEs' programme. EDCTP regional networks of excellence: initial merits for planned clinical trials in Africa. BMC Public Health 13: 258 (2013)

  • M.F. Muellenbeck, B. Ueberheide, B. Amulic, A. Epp, D. Fenyo, C.E. Busse, M. Esen, M. Theisen, B. Mordmüller, H. Wardemann: Atypical and classical memory B cells produce Plasmodium falciparum neutralizing antibodies. The Journal of Experimental Medicine 210(2): 389-399 (2013)

  • D. Nkosi, S. Janssen, X. Padanilam, R. Louw, C.N. Menezes, M.P. Grobusch: Factors influencing specialist care referral of multidrug- and extensively drug-resistant tuberculosis patients in Gauteng/South Africa: a descriptive questionnaire-based study. BMC Health Services Research 13: 268 (2013)

  • F. Ntoumi, J.C. Vouvoungui, R. Ibara, M. Landry, A. Sidibé: Malaria burden and case management in the Republic of Congo: limited use and application of rapid diagnostic tests results. BMC Public Health 13: 135 (2013)

  • D. Nurjadi, E. Herrmann, I. Hinderberger, P. Zanger: Impaired β-defensin expression in human skin links DEFB1 promoter polymorphisms with persistent Staphylococcus aureus nasal carriage.
    Journal of Infectious diseases 207(4): 666-674 (2013)

  • S.I. Oyedeji, H.O. Awobode, C. Anumudu, J. Kun: Genetic diversity of Plasmodium falciparum isolates from naturally infected children in north-central Nigeria using the merozoite surface protein-2 as molecular marker. Asian Pacific Journal of Tropical Medicine 6(8): 589-594 (2013)

  • M. Rebelo, C. Sousa, H.M. Shapiro, M. M. Mota, M.P. Grobusch, T. Hänscheid: A Novel Flow Cytometric Hemozoin Detection Assay for Real-Time Sensitivity Testing of Plasmodium falciparum. PLoS One 8(4): e61606 (2013)

  • F. Schaumburg, A. Alabi, C. von Eiff, A. Flamen, H. Traore, M.P. Grobusch, G. Peters, P.G. Kremsner, M. van der Linden: Streptococcus pneumoniae colonization in remote African Pygmies.
    Transactions of the Royal Society of Tropical Medicine and Hygiene 107(2): 105-109 (2013)

  • F. Schaumburg, A. Alabi, C. Kokou, M.P. Grobusch, R. Köck, H. Kaba, K. Becker, A.A. Adegnika, P.G. Kremsner, G. Peters, A. Mellmann: High burden of extended-spectrum β-lactamase-producing Enterobacteriaceae in Gabon. Journal of Antimicrobial Chemotherapy 68(9): 2140-2143 (2013)

  • F. Schaumburg, B. Biallas, A.S. Alabi, M.P. Grobusch, E.N. Feugap, B. Lell, A. Mellmann, G. Peters, P.G. Kremsner, K. Becker, A.A. Adegnika: Clonal structure of Staphylococcus aureus colonizing children with sickle cell anaemia and healthy controls. Epidemiology and Infection 141(8): 1717-1720 (2013)

  • F. Schaumburg, B. Biallas, E. Ngoune Feugap, A.S. Alabi, B. Mordmüller, P.G. Kremsner, M.P. Grobusch, B. Lell, M. van der Linden, G. Peters, A.A. Adegnika: Carriage of encapsulated bacteria in Gabonese children with sickle cell anaemia. Clinical Microbiology and Infection 19(3): 235-241 (2013)

  • V. Shinde, P. Marcinek, D.S. Rani, S.R. Sunder, S. Arun, S. Jain, I. Nath, K. Thangaraj, T.P. Velavan, V.L. Valluri: Genetic evidence of TAP1 gene variant as a susceptibility factor in Indian leprosy patients. Human Immunology 74(6): 803-807 (2013)

  • S.M. Stolp, M.A. Huson, S. Janssen, J.O. Beyeme, M.P. Grobusch: Tuberculosis patients hospitalized in the Albert Schweitzer Hospital, Lambaréné, Gabon-a retrospective observational study. Clinical Microbiology and Infection 19(11): E499-E501 (2013)

  • B.T. Sy, B.A. Ratsch, N.L. Toan, H. Song le, C. Wollboldt, A. Bryniok, H.M. Nguyen, H.V. Luong, T.P. Velavan, H. Wedemeyer, P.G. Kremsner, C.T. Bock: High Prevalence and Significance of Hepatitis D Virus Infection among Treatment-Naïve HBsAg-Positive Patients in Northern Vietnam.
    PLoS One 8(10): e78094 (2013).

  • N.L. Toan, B.T. Sy, H. Song le, H.V. Luong, N.T. Binh, V.Q. Binh, R. Kandolf, T.P. Velavan, P.G. Kremsner, C.T. Bock: Co-infection of human parvovirus B19 with Plasmodium falciparum contributes to malaria disease severity in Gabonese patients. BMC Infectious Diseases 13: 375-384 (2013).

  • H.V. Tong, N.L. Toan, L.H. Song, C.T. Bock, P.G. Kremsner, T.P. Velavan: Hepatitis B virus-induced hepatocellular carcinoma: functional roles of MICA variants. Journal of Viral Hepatitis 20(10): 687-698 (2013).

  • S. Tschan, A.J. Brouwer, P.R. Werkhoven, A.M. Jonker, L. Wagner, S. Knittel, M.N. Aminake, G. Pradel, F. Joanny, R.M. Liskamp, B. Mordmüller: Broad-spectrum antimalarial activity of peptido sulfonyl fluorides, a new class of proteasome inhibitors. Antimicrobial Agents and Chemotherapy 57(8): 3576-3584 (2013).

  • B.J. Visser, R.W. Wieten, I.M. Nagel, M.P. Grobusch: Serum lipids and lipoproteins in malaria - a systematic review and meta-analysis. Malaria Journal 12: 442 (2013).

  • K. Wahlers, C.N. Menezes, T. Romig, P. Kern, M.P. Grobusch: Cystic echinococcosis in South Africa: the worst yet to come? Acta Tropica 128(1): 1-6 (2013).

  • G.M. Warimwe, H.A. Fletcher, A. Olotu, S.T. Agnandji, A.V. Hill, K. Marsh, P. Bejon: Peripheral blood monocyte-to-lymphocyte ratio at study enrollment predicts efficacy of the RTS,S malaria vaccine: analysis of pooled phase II clinical trial data. BMC Medicine 11(1): 184-189 (2013)

  • D. Wichmann, S. Poppert, H. Von Thien, J. Clerinx, S. Dieckmann, M. Jensenius, P. Parola, J. Richter, M. Schunk, A. Stich, P. Zanger, G.D. Burchard, E. Tannich: Prospective European-wide multicentre study on a blood based real-time PCR for the diagnosis of acute schistosomiasis.
    BMC Infectious Diseases 13: 55 (2013)

  • A.E. Wiria, F. Hamid, L.J. Wammes, M.M. Kaisar, L. May, M:A:Prasetyani, S. Wahyuni, Y. Djuardi, I. Ariawan, H. Wibowo, B. Lell, R. Sauerwein, G.T. Brice, I. Sutanto, L. van Lieshout, A.J. de Craen, R. van Ree, J.J. Verweij, R. Tsonaka, J.J. Houwing-DuistermaatJ, A.J. Luty, E. Sartono, T. Supali, M. Yazdanbakhsh: The effect of three-monthly albendazole treatment on malarial parasitemia and allergy: a household-based cluster-randomized, double-blind, placebo-controlled trial.PLoS One 8(3): e57899 (2013)

  • T.G. Woldearegai, P.G. Kremsner, J.F. Kun, B. Mordmüller: Plasmodium vivax malaria in Duffy-negative individuals from Ethiopia. Transactions of the Royal Society for Tropical Medicine and Hygiene 107(5): 328-331 (2013).

  • WorldWide Antimalarial Resistance Network (WWARN) DP Study Group. The effect of dosing regimens on the antimalarial efficacy of dihydroartemisinin-piperaquine: a pooled analysis of individual patient data. PLoS Medicine 12: e1001564 (2013)

  • N. Wressnigg, E.M. Pöllabauer, G. Aichinger, D. Portsmouth, A. Löw-Baselli, S. Fritsch, I. Livey, B.A. Crowe, M. Schwendinger, P. Brühl, A. Pilz, T. Dvorak, J. Singer, C. Firth, B. Luft, B. Schmitt, M. Zeitlinger, M. Müller, H. Kollaritsch, M. Paulke-Korinek, M. Esen, P.G. Kremsner, H.J. Ehrlich, P.N. Barrett: Safety and immunogenicity of a novel multivalent OspA vaccine against Lyme borreliosis in healthy adults: a double-blind, randomised, dose-escalation phase 1/2 trial.
    Lancet Infectious Diseases 13(8): 680-689 (2013).

  • P. Zanger, D. Nurjadi, J. Gabor, M. Gaile, P.G. Kremsner. Effectiveness of rifaximin in prevention of diarrhoea in individuals travelling to south and southeast Asia: a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet Infectious Diseases 13(11): 946-954 (2013)

  • P. Zanger, S. Gabrysch: Leishmaniasis in the era of tumor necrosis factor alpha antagonist therapy--a research agenda for Europe. Eurosurveillance 18(30): 20542 (2013).

Zertifikate und Verbände

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