Medizinische Klinik
Innere Medizin VII
Institut für Tropenmedizin, Reisemedizin, Humanparasitologie

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Adresse: Wilhelmstraße 27
72074 Tübingen

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Publikationen 2015

  • S. Abdulla, I. Adam, G.O. Adjei et al. Group Author(s): WWARN Artemisinin based Combination Therapy (ACT) Africa Baseline Study Group. Clinical determinants of early parasitological response to ACTs in African patients with uncomplicated falciparum malaria: a literature review and meta-analysis of individual patient data. BMC Medicine 13: 212 (2015)

  • S. Abdulla, E. Ashley, Q. Bassat et al. Group Author(s): WWARN Parasite Clearance Study Grp: Baseline data of parasite clearance in patients with falciparum malaria treated with an artemisinin derivative: an individual patient data meta-analysis. Malaria Journal 14: 359 (2015)

  • S.T. Agnandji, J.F. Fernandes, E.B. Bache, M. Ramharter: Clinical development of RTS,S/AS malaria vaccine: a systematic review of clinical Phase I-III trials. Future Microbiology 10: 1553-1578 (2015)

  • A. Ajua, B. Lell, S.T. Agnandji, K.P. Asante, S. Owusu-Agyei, G. Mwangoka, M. Mpina, N. Salim, M. Tanner, S. Abdulla, J. Vekemans, E. Jongert, M. Lievens M. Cambron, C.F. Ockenhouse, P.G.Kremsner, B. Mordmüller: The effect of immunization schedule with the malaria vaccine candidate RTS,S/AS01E on protective efficacy and anti-circumsporozoite protein antibody avidity in African infants. Malaria Journal 14(1): 605 (2015)

  • J.S. Antony, O. Ojurongbe, P.G. Kremsner, T.P. Velavan: Lectin Complement Protein Collectin 11 (CL-K1) and Susceptibility to Urinary Schistosomiasis. PLoS Neglected Tropical Diseases 9(3): e0003647 (2015)

  • J.S. Antony, O. Ojurongbe, C.G. Meyer, K. Thangaraj, A. Mishra, P.G. Kremsner, T-P. Velavan: Correlation of Interleukin-6 levels and lectins during Schistosoma haematobium infection. Cytokine 76(2): 152-155 (2015)

  • U. Ateba-Ngoa, A.A. Adegnika, J.F. Zinsou, R.F. Kassa Kassa, H. Smits, M. Massinga-Loembe, B. Mordmüller, P.G. Kremsner, M. Yazdanbakhsh: Cytokine and chemokine profile of the innate and adaptive immune response of schistosoma haematobium and plasmodium falciparum single and co-infected school-aged children from an endemic area of Lambaréné, Gabon. Malaria Journal 14(1): 94 (2015)

  • S. Bélard, N Toepfner, B. Arnold, A.S. Alabi, R. Berner: β-hemolytic streptococcal throat carriage and tonsillopharyngitis: a cross-sectional prevalence study in Gabon, Central Africa. Infection 43(2): 177-183 (2015)

  • S. Belard, N. Toepfner, M. Capan-Melser, G. Mombo-Ngoma, R. Zoleko-Manego, M. Groger, P.B. Matsiegui, S.T. Agnandji, A.A. Adegnika, R. González, P.G. Kremsner C. Menendez, M. Ramharter, R. Berner: Streptococcus agalactiae Serotype Distribution and Antimicrobial Susceptibility in Pregnant Women in Gabon, Central Africa. Scientific Reports 5: 17281 (2015)

  • S. Bélard, S. Janssen, K.K. Osbak, A.A. Adegnika, M. Ondounda, M.P. Grobusch: Limited access to drugs for resistant tuberculosis: a call to action. Journal of Public Health 37(4): 691-693 (2015)

  • A. Benoit, J. Beran, J.M. Devaster, M. Esen, O. Launay, G. Leroux-Roels, J.E. McElhaney, L. Oostvogels, G.A: van Essen, M. Gaglani, L.A. Jackson, T. Vesikari, C. Legrand, F. Tibaldi, B.L. Innis, W. Dewé W: Hemagglutination Inhibition Antibody Titers as a Correlate of Protection Against Seasonal A/H3N2 Influenza Disease. Open Forum Infectious Diseases 2(2):ofv067 (2015)

  • E.M. Bijker, S. Borrmann, S.H. Kappe, B. Mordmüller, B.K. Sack, S.M. Khan: Novel approaches to whole sporozoite vaccination against malaria. Vaccine 33(52): 7462-7468

  • E. Birnie, W.J. Wiersinga, D. Limmathurotsakul, M.P. Grobusch: Melioidosis in Africa: should we be looking more closely? Future Microbiology 10: 273-281 (2015)

  • A.L. Bissinger, C. Fehrle, C.R. Werner, U.M. Lauer, N.P. Malek, C.P. Berg: Epidemiology and Genotyping of Patients with Chronic Hepatitis: Genotype Shifting Observed in Patients from Central Europe. Polish Journal of Microbiology 64 (1): (15-21) (2015)

  • C.G. Blumentrath, M.P. Grobusch, P.B. Matsiégui, F. Pahlke, R. Zoleko-Manego, S. Nzenze-Aféne, B. Mabicka, M. Sanguinetti, P.G. Kremsner, F. Schaumburg: Classification of Rhinoentomophthoromycosis into Atypical, Early, Intermediate, and Late Disease: A Proposal. PLoS Neglected Tropical Diseases 9(10): e0003984 (2015)

  • K. Brücher, T. Gräwert, S. Konzuch, J. Held, C. Lienau, C. Behrendt, B. Illarionov, L. Maes, A. Bacher, S. Wittlin, B. Mordmüller, M. Fischer, T. Kurz: Prodrugs of reverse fosmidomycin analogues. Journal of Medicinal Chemistry 58(4): 2025-2035 (2015)

  • S. Brückner, S.T. Agnandji, S. Berberich, E. Bache, J.F. Fernandes, B. Schweiger, M. Massinga Loembe, T. Engleitner, B. Lell, B. Mordmüller, A.A. Adegnika, M. Yazdanbakhsh, P.G. Kremsner, M. Esen: Effect of Antihelminthic Treatment on Vaccine Immunogenicity to a Seasonal Influenza Vaccine in Primary School Children in Gabon: A Randomized Placebo-Controlled Trial. PLoS Neglected Tropical Diseases 9(6): e0003768 (2015). IF: 4,446

  • M. Capan-Melser, G. Mombo Ngoma, D. Akerey-Diop, A. Basra, H. Würbel, M. Groger, J.R. Mackanga, R. Zoleko-Manego, U. Schipulle, J. Schwing, F. Lötsch, K. Rehman, P.B. Matsiegui, S.T. Agnandji, A.A: Adegnika, S. Bélard, R. González, P.G. Kremsner, C. Menendez, M. Ramharter: Evaluation of intermittent preventive treatment of malaria against group B Streptococcus colonization in pregnant women: a nested analysis of a randomized controlled clinical trial of sulfadoxine/pyrimethamine versus mefloquine. Journal of Antimicrobial Chemotherapy 70(6): 1898-1902 (2015)

  • M. Capan-Melser, G. Mombo-Ngoma, D. Akerey-Diop, A. Basra, R. Manego-Zoleko, H. Würbel, F. Lötsch, M. Groger, M. Skoll, J. Schwing, U. Schipulle, P.B. Matsiegui, R. González, C. Menendez, P.G. Kremsner, A.A. Adegnika, S.T. Agnandji, M. Ramharter: Epidemiology of Human Herpes Virus 8 in Pregnant Women and their Newborns - A cross-sectional delivery survey in Central Gabon. International Journal of Infectious Diseases 39: 16-19 (2015)

  • J. Ehrhardt, A.S. Alabi, T. Kuczius, F.F. Tsombeng, K. Becker, P.G. Kremsner, F. Schaumburg, M. Esen: Population structure of Legionella spp. from environmental samples in Gabon, 2013. Infection, Genetics and Evolution 33: 299-303 (2015)

  • D.H. Esposito, B.M. Rosenthal, G. Slesak, D. Tappe, R. Fayer, E. Bottieau, C. Brown, M.P. Grobusch, D. Malvy, F. von Sonnenburg, M.J. Sotir, F. Steiner, P. Zanger, P.E. Kozarsky: Reply to Italiano et al. Clinical Infectious Diseases 60 (7): 1135-1136 (2015)

  • J.F. Fernandes, B. Lell, S.T. Agnandji, R.M. Obiang, Q. Bassat, P.G. Kremsner, B. Mordmüller, M.P.Grobusch: Fosmidomycin as an antimalarial drug: a meta-analysis of clinical trials. Future Microbiology 10: 1375-1390 (2015)

  • J.J. Gabor, N.G. Schwarz, M. Esen, P.G. Kremsner, M.P. Grobusch: Influenza A and Parvovirus B19 Seropositivity Rates in Gabonese Infants. American Journal of Tropical Medicine and Hygiene 93(2): 407-409 (2015)

  • L.S. Ghoma-Linguissi, D.F. Ebourombi, A. Sidibe, T.S. Kivouele, J.C. Vouvoungui, P. Poulain, F. Ntoumi: Factors influencing acceptability of voluntary HIV testing among pregnant women in Gamboma, Republic of Congo. BMC Research Notes 8: 652 (2015)

  • G.P. Gómez-Pérez, A. Legarda, J. Muñoz, B.K. Sim, M.R. Ballester, C. Dobaño, G. Moncunill, J.J. Campo, P. Cisteró, A. Jimenez, D. Barrios, B. Mordmüller, J. Pardos, M. Navarro, C.J. Zita, C.A: Nhamuave, A.L. García-Basteiro, A. Sanz, M. Aldea, A. Manoj, A. Gunasekera, P.F. Billingsley, J.J. Aponte, E.R. James, C. Guinovart, R.M. Antonijoan, P.G. Kremsner, S.L. Hoffman, P.L. Alonso:
    Controlled human malaria infection by intramuscular and direct venous inoculation of cryopreserved Plasmodium falciparum sporozoites in malaria-naïve volunteers: effect of injection volume and dose on infectivity rates. Malaria Journal 14(1): 306 (2015)

  • O. Goovaerts, W. Jennes, M. Massinga-Loembé, P. Ondoa, A. Ceulemans, C. Vereecken, W. Worodria, H. Mayanja-Kizza, R. Colebunders, L. Kestens; TB-IRIS Study Group. Lower Pre-Treatment T Cell Activation in Early- and Late-Onset Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome. PLoS One 10(7): e0133924 (2015)

  • M.S.Hede, P.N. Okorie, S.K. Fruekilde, S. Fjelstrup, J. Thomsen, O. Franch, C. Tesauro, M.T. Bugge, M. Christiansen, S. Picot, F. Lotsch, G. Mombo-Ngoma,J. Mischlinger, AA. Adegnika, F.S. Pedersen, Yi-Ping Ho, E. Petersen, M. Stougaard, M. Ramharter, B.R. Knudsen: Refined Method for Droplet Microfluidics-Enabled Detection of Plasmodium falciparum Encoded. Micromachines 6 (10), 1505-1513 (2015)

  • J. Hegewald, R.G. Gantin, C.J. Lechner, X. Huang, A. Agosssou, Y.F. Agbeko, P.T. Soboslay, C. Köhler: Cellular cytokine and chemokine responses to parasite antigens and fungus and mite allergens in children co-infected with helminthes and protozoa parasites. Journal of Inflammation 12: 5 (2015)

  • J. Held, S. Jeyaraj, A. Kreidenweiss: Antimalarial compounds in Phase II clinical development. Expert Opinion on Investigational Drugs 24(3): 363-382 (2015)

  • J. Held, C. Supan, C.L. Salazar, H. Tinto, L.N. Bonkian, A. Nahum, B. Moulero, A. Sié, B. Coulibaly, S.B. Sirima, M. Siribie, N. Otsyula, L. Otieno, A.M. Abdallah, R. Kimutai, M. Bouyou-Akotet, M. Kombila, K. Koiwai, C. Cantalloube, C. Din-Bell, E. Djeriou, J. Waitumbi, B. Mordmüller, D. Ter-Minassian, B. Lell, P.G. Kremsner: Ferroquine and artesunate in African adults and children with Plasmodium falciparum malaria: a phase 2, multicentre, randomised, double-blind, dose-ranging, non-inferiority study. Lancet Infectious Diseases 15(12) 1409-1419 (2015)

  • S. Howe, D. Zöphel, H. Subbaraman, C. Unger, J. Held, T. Engleitner, W.H. Hoffmann, A. Kreidenweiss: Lactate as a Novel Quantitative Measure of Viability in Schistosoma mansoni Drug Sensitivity Assays. Antimicrobial Agents and Chemotherapy 59(2): 1193-1199 (2015)

  • C.Y. Hu, X.A. Zhang, C.G. Meyer, T. Thye, W. Liu, W.C. Cao: Polymorphism of X-linked CD40 ligand gene associated with pulmonary tuberculosis in the Han Chinese population. Genes and Immunity 16(6): 399-404

  • A. Huson, S.S. Zeerleder, G. van Mierlo, D. Wouters, M.P. Grobusch, T. van der Poll: HIV infection is associated with elevated nucleosomes in asymptomatic patients and during sepsis or malaria. Journal of Infection 71(2): 266-269 (2015)

  • M.A. Huson, D. Wouters, G. van Mierlo, M.P. Grobusch, S.S: Zeerleder, T. van der Poll: HIV Coinfection Enhances Complement Activation During Sepsis. Journal of Infectious Diseases 212(3): 474-483 (2015)

  • A. Huttner, J.A. Dayer, S. Yerly, C. Combescure, F. Auderset, J. Desmeules, M. Eickmann, A: Finckh, A.R: Goncalves, J.W. Hooper, G. Kaya, V. Krähling, S. Kwilas, B. Lemaître, A. Matthey, P. Silvera, S. Becker, P.E: Fast, V. Moorthy, M.P. Kieny MP, L. Kaiser, C.A: Siegrist, VSV-Ebola Consortium: Kremsner, Brosnahan, Agnandji, Krishna: The effect of dose on the safety and immunogenicity of the VSV Ebola candidate vaccine: a randomised double-blind, placebo-controlled phase 1/2 trial. Lancet Infectious Diseases 15(10): 1156-1166 (2015)

  • Jannasch M, Groeber F, Brattig NW, Unger C, Walles H, Hansmann J. Development and application of three-dimensional skin equivalents for the investigation of percutaneous worm invasion. Experimental Parasitology 150: 22-30 (2015)

  • S. Janssen, S. Hermans, M. Knap, A. Moekotte, E.G. Rossatanga, A.A. Adegnika, S. Bélard, T. Hänscheid, M.P. Grobusch: Impact of Anti-Retroviral Treatment and Cotrimoxazole Prophylaxis on Helminth Infections in HIV-Infected Patients in Lambaréné, Gabon. PLoS Neglected Tropical Diseases 9(5): e0003769 (2015)

  • S. Janssen, R.W. Wieten, S. Stolp, A.L. Cremers, E:G: Rossatanga, K. Klipstein-Grobusch, S. Belard, M.P. Grobusch: Factors Associated with Retention to Care in an HIV Clinic in Gabon, Central Africa. PLoS One 10(10): e0140746 (2015)

  • A.K. Käser, P.M. Arguin, P.L. Chiodini, V. Smith, J. Delmont, B.C. Jiménez, A. Färnert, M. Kimura, M. Ramharter, M.P. Grobusch, P. Schlagenhauf: Imported malaria in pregnant women: A retrospective pooled analysis. Travel Medicine and Infectious Disease 13(4): 300-310 (2015)

  • J. Kegele, H. Hurth, P. Lackner, A. Enimil, J. Sylverkin, D. Ansong, C. Nkyi, B. Bonsu, T. Agbenyega, V.H. Schartinger, E. Schmutzhard, P. Zorowka, P. Kremsner, J. Schmutzhard: Otoacoustic emission testing in Ghanaian children with sickle-cell disease. Tropical Medicine & International Health 20(9): 1209-1212 (2015)

  • F. Koukouikila-Koussounda, D. Bakoua, A. Fesser, M. Nkombo, C. Vouvoungui, F. Ntoumi:
    High prevalence of sulphadoxine-pyrimethamine resistance-associated mutations in Plasmodium falciparum field isolates from pregnant women in Brazzaville, Republic of Congo.
    Infection, Genetics and Evolution 33: 32-36 (2015)C. Kraef, A.S. Alabi, G. Peters, K. Becker, P.G. Kremsner, E.G. Rossatanga, A. Mellmann, M.P. Grobusch, P. Zanger, F. Schaumburg: Co-detection of Panton-Valentine leukocidin encoding genes and cotrimoxazole resistance in Staphylococcus aureus in Gabon: implications for HIV-patients' care. Frontiers in Microbiology 6:60 (2015)

  • S. Krishna, S. Ganapathi, I.C. Ster, M.E. Saeed, M. Cowan, C: Finlayson, H. Kovacsevics, H. Jansen, P.G Kremsner, T. Efferth, D. Kumar D: A Randomised, Double Blind, Placebo-Controlled Pilot Study of Oral Artesunate Therapy for Colorectal Cancer. EBioMedicine. 2(1): 82-90 (2015)

  • F. Kurth, M. Develoux, M. Mechain, J. Clerinx, S: Antinori, I.E. Gjørup, J. Gascon, K. Mørch, E. Nicastri, M. Ramharter, A: Bartoloni, L. Visser, T. Rolling, P. Zanger, G. Calleri, J. Salas-Coronas, H. Nielsen, G: Just-Nübling, A. Neumayr, A: Hachfeld, M.L. Schmid, P. Antonini, P. Pongratz, P. Kern, J. Saraiva da Cunha, A. Soriano-Arandes, M. Schunk, N. Suttorp, C. Hatz, T. Zoller; TropNet Severe Malaria Investigator Group: Intravenous Artesunate Reduces Parasite Clearance Time, Duration of Intensive Care, and Hospital Treatment in Patients With Severe Malaria in Europe: The TropNet Severe Malaria Study. Clinical Infectious Diseases 61(9): 1441-1444 (2015)

  • H. Lal, A.L. Cunningham, O. Godeaux, R: Chlibek, J. Diez-Domingo, S.J. Hwang, M.J. Levin, J.E. McElhaney, A. Poder, J. Puig-Barberà, T. Vesikari, D. Watanabe, L. Weckx, T. Zahaf, T:C. Heineman TC, ZOE-50 Study Group (M. Esen et al.): Efficacy of an adjuvanted herpes zoster subunit vaccine in older adults. New England Journal of Medicine 372(22): 2087-2096 (2015)

  • A. Lalremruata, M. Magris, S. Vivas-Martínez, M. Koehler, M. Esen, P. Kempaiah, S. Jeyaraj, D.J. Perkins, B. Mordmüller, W.G. Metzger: Natural infection of Plasmodium brasilianum in humans: Man and monkey share quartan malaria parasites in the Venezuelan Amazon. EBioMedicine 2(9): 1186-1189

  • S. Lanini, A. Zumla, J.P. Ioannidis, A.D. Caro, S. Krishna, L. Gostin, E. Girardi, M. Pletschette, G: Strada, A. Baritussio, G. Portella, G. Apolone, S. Cavuto, R. Satolli, P. Kremsner, F. Vairo, G. Ippolito: Are adaptive randomised trials or non-randomised studies the best way to address the Ebola outbreak in west Africa? Lancet Infectious Diseases 15(6): 738-745 (2015)

  • L.S. Linguissi, C.J. Vouvoungui, P: Poulain, G.B. Essassa, S. Kwedi, F. Ntoumi: Diagnosis of smear-negative pulmonary tuberculosis based on clinical signs in the Republic of Congo. BMC Research Notes 8(1): 804 (2015)

  • F. Lötsch, L. Auer-Hackenberg, M. Groger, K. Rehman, V. Morrison, E. Holmes, S. Parveen, C. Plumpton, W. Clyne, S. de Geest, F: Dobbels, B. Vrijens, P. Kardas, D. Hughes, M. Ramharter: Adherence of patients to long-term medication: a cross-sectional study of antihypertensive regimens in Austria. Wiener Klinische Wochenschrift 127(9-10): 379-384 (2015)

  • M. Makara, M. Sulyok, O. Csacsovszki, Z. Sulyok, I. Vályi-Nagy: Successful treatment of HCV-associated cryoglobulinemia with ombitasvir/paritaprevir/ritonavir, dasabuvir and ribavirin: A case report. Journal of Clinical Virology 72: 66-68 (2015)

  • F. Marks, B. Nyambat, Z.Y. Xu, V. von Kalckreuth, P.E. Kilgore, H.J. Seo, Y. Du, S.E. Park, J. Im, F. Konings, C.G. Meyer, T.F. Wierzba, J.D. Clemens: Vaccine introduction in the Democratic People's Republic of Korea. Vaccine. 33(20): 2297-2300 (2015)

  • D. Medaglini, A.M. Harandi, T.H. Ottenhoff, C.A. Siegrist, V.E. Consortium (Brosnahan, Kremsner, Agnandji, Lell): Ebola vaccine R&D: Filling the knowledge gaps. Science Translational Medicine 7(317): 317ps24 (2015)

  • W.G. Metzger, C. Köhler, B. Mordmüller: Lessons from a modern review of the smallpox eradication files. Journal of the Royal Society of Medicine 108(12): 473-477 (2015)

  • A.Mishra, J.S. Antony, P. Sundaravadivel, H.V. Tong, C.G. Meyer, R.D. Jalli, T.P. Velavan, K. Thangaraj: Association of Ficolin-2 Serum Levels and FCN2 Genetic Variants with Indian Visceral Leishmaniasis. PLoS One. 10(5): e0125940 (2015)

  • A. Mishra, J.S. Antony, P. Gai, P. Sundaravadivel, T. Hoang van, A.N. Jha, L. Singh, T.P. Velavan, K. Thangaraj: Mannose-binding Lectin (MBL) as a susceptible host factor influencing Indian Visceral Leishmaniasis. Parasitology International 64(6): 591-596 (2015)

  • G. Mombo-Ngoma, J.R. Mackanga, A. Basra, M. Capan, R.Z. Manego, A.A. Adegnika, F. Lötsch, M. Yazdanbakhsh, R. González, C. Menendez, B. Mabika, P.B. Matsiegui, P.G. Kremsner, M. Ramharter: Loa loa Infection in Pregnant Women, Gabon. Emerging Infectious Diseases 21(5): 899a-901 (2015)

  • B. Mordmüller, C. Supan, K.L. Sim, G.P. Gómez-Pérez, C.L. Ospina Salazar, J. Held, S. Bolte, M. Esen, S. Tschan, F. Joanny, C. Lamsfus Calle, S.J. Löhr, A. Lalremruata, A. Gunasekera, E.R. James, P.F. Billingsley, A. Richman, S. Chakravarty, A. Legarda, J. Muñoz, R.M. Antonijoan, M.R. Ballester, S.L. Hoffman, P.L. Alonso, P.G. Kremsner: Direct venous inoculation of Plasmodium falciparum sporozoites for controlled human malaria infection: a dose-finding trial in two centres. Malaria Journal 14(1): 117 (2015)

  • M. Ndounga, P.I. Mayengue, P.N. Casimiro, F. Koukouikila-Koussounda, M. Bitemo, B. Diassivy Matondo, L.A. Ndounga Diakou, L.K. BascoK, F. Ntoumi: Artesunate-amodiaquine versus artemether-lumefantrine for the treatment of acute uncomplicated malaria in Congolese children under 10 years old living in a suburban area: a randomized study. Malaria Journal 14(1): 423 (2015)

  • D.E. Neafsey, M. Juraska, T. Bedford, D. Benkeser, C. Valim, A. Griggs, M. Lievens, S. Abdulla, S. Adjei, T. Agbenyega, S.T: Agnandji, P. Aide, S. Anderson, D. Ansong, J.J. Aponte, K.P. AsanteP, B. Bejon, A.J. Birkett, M. Bruls, K.M. Connolly, U. D'Alessandro, C. Dobaño S: Gesase, B: Greenwood, J. Grimsby, H. Tinto, M.J. Hamel, I. Hoffman, P. Kamthunzi, S. Kariuki, P.G. Kremsner, A. Leach, B. Lell, N.J. Lennon, J. Lusingu, K. Marsh, F: Martinson, J.T. Molel, E.L. Moss, P. Njuguna, C.F. Ockenhouse, B.R. Ogutu, W. Otieno, L. Otieno, K. Otieno, S. Owusu-Agyei, D:J: Park, K. Pellé, D. Robbins, C. Russ, E.M. Ryan, J. Sacarlal, B. Sogoloff, H. Sorgho, M. Tanner, T. Theander, I. Valea, S.K. Volkman, Q.Yu, D. Lapierre, B:W. Birren, P.B: Gilbert PB, D.F. Wirth: Genetic Diversity and Protective Efficacy of the RTS,S/AS01 Malaria Vaccine. New England Journal of Medicine 373(21): 2025-2037 (2015)

  • C. Nichols, L.M. Cruz Espinoza, V. von Kalckreuth, P. Aaby, M. Ahmed El Tayeb, M. Ali, A. Aseffa, M. Bjerregaard-Andersen, R.F. Breiman, L. Cosmas, J.A. Crump, D.M. Dekker, A. Gassama Sow, N. Gasmelseed, J.T. Hertz, J. Im, L.P. Kabore, K.H. KeddyH, F. Konings, S. Valborg Løfberg, C.G. Meyer, J.M. Montgomery, A. Niang, A. Njariharinjakamampionona, B. Olack, G.D. Pak, U. Panzner, J.K. Park, S.E. Park, H. Rabezanahary, J.P. Rakotondrainiarivelo, R: Rakotozandrindrainy, T.M. Raminosoa, M.P. Rubach, M. Teferi, H.J. Seo, A. Sooka, A. Soura, A. Tall, T. Toy, B. Yeshitela, J.D. Clemens, T.F. Wierzba, S. Baker, F. Marks: Bloodstream Infections and Frequency of Pretreatment Associated With Age and Hospitalization Status in Sub-Saharan Africa. Clinical Infectious Diseases 61 Suppl 4: S372-379 (2015)

  • C.N. Nguetse, P.G. Kremsner, T.P. Velavan: FOXO3A regulatory polymorphism and susceptibility to severe malaria in Gabonese children. Immunogenetics 67(2):67-71 (2015)

  • M.A. Nielsen, M. Resende, W.A: de Jongh, S.B: Ditlev, B. Mordmüller, S: Houard, N.T. Ndam, MØ Agerbæk, M. Hamborg, A. Massougbodji, S. Issifou, A: Strøbæk, L. Poulsen, O. Leroy O, P.G. Kremsner, J.P. Chippaux, A.J. Luty, P. Deloron, T.G: Theander, C. Dyring, A. Salanti: The Influence of Sub-Unit Composition and Expression System on the Functional Antibody Response in the Development of a VAR2CSA Based Plasmodium falciparum Placental Malaria Vaccine. PLoS One 10(9): e0135406 (2015)

  • D. Nurjadi, B. Friedrich-Jänicke, J. Schäfer, P.J. Van Genderen, A. Goorhuis, A. Perignon, A. Neumayr, A. Mueller, A. Kantele, M. Schunk, J. Gascon, A. Stich, C. Hatz, E. Caumes, M.P. Grobusch, R. Fleck, F.P. Mockenhaupt, P. Zanger: Skin and soft tissue infections in intercontinental travellers and the import of multi-resistant Staphylococcus aureus to Europe. Clinical Microbiology and Infection 21(6): 567.e1-567.e10 (2015)

  • L.M. Ogorodova, O.S. Fedorova, B. Sripa, V.A. Mordvinov, A.V: Katokhin, J. Keiser, P. Odermatt, P.J. Brindley, O.A. Mayboroda, T.P. Velavan, M.B. Freidin, A.E. Sazonov, I.V. Saltykova, M.Y. Pakharukova, Y.V. Kovshirina, K. Kaloulis, O.Y. Krylova, M. Yazdanbakhsh M; TOPIC Consortium: Opisthorchiasis: an overlooked danger. PLoS Neglected Tropical Diseases 9(4): e0003563 (2015)

  • O. Ojurongbe, J.S. Antony, H. Van Tong, C.G: Meyer, A:A: Akindele, O.R. Sina-Agbaje, P.G: Kremsner, T:P.Velavan: Low MBL-associated serine protease 2 (MASP-2) levels correlate with urogenital schistosomiasis in Nigerian children. Tropical Medicine and International Health 20(10): 1311-1319 (2015)

  • O.O Oluyinka, H.V. Tong, S. Bui Tien, A.H. Fagbami, O. Adekanle, O. Ojurongbe, C.T. Bock, P.G. Kremsner, T.P.Velavan: Occult Hepatitis B Virus Infection in Nigerian Blood Donors and Hepatitis B Virus Transmission Risks. PLoS One 10(7): e0131912 (2015)

  • E.D. Owusu, B.J. Visser, I.M. Nagel, P.F. Mens, M.P.Grobusch: The Interaction Between Sickle Cell Disease and HIV Infection: A Systematic Review. Clinical Infectious Diseases 60(4): 612-626 (2015)

  • J. Pfeil, S. Borrmann, Q. Bassat, M. Mulenga, A. Talisuna, Y. Tozan: An Economic Evaluation of the Posttreatment Prophylactic Effect of Dihydroartemisinin–Piperaquine Versus Artemether–Lumefantrine for First-Line Treatment of Plasmodium falciparum Malaria Across Different Transmission Settings in Africa. American Journal of Tropical Medicine and Hygiene 93: 961-966 (2015)

  • Prado M, Eickel N, De Niz M, Heitmann A, Agop-Nersesian C, Wacker R, Schmuckli-Maurer J, Caldelari R, Janse CJ, Khan SM, May J, Meyer CG, Heussler VT. Long-term live imaging reveals cytosolic immune responses of host hepatocytes against Plasmodium infection and parasite escape mechanisms. Autophagyy 11(9): 1561-1579 (2015)

  • F. Ratzinger, M. Dedeyan, M. Rammerstorfer, T. Perkmann, H. Burgmann, A. Makristathis, G. Dorffner, F. Loetsch, A. Blacky, M. Ramharter: Neither Single nor a Combination of Routine Laboratory Parameters can Discriminate between Gram-positive and Gram-negative Bacteremia. Scientific Reports 5: 16008 (2015)

  • M. Rebelo, C. Tempera, J.F. Fernandes, M.P. Grobusch, T. Hänscheid: Assessing anti-malarial drug effects ex vivo using the haemozoin detection assay. Malaria Journal 14(1): 140 (2015)

  • T.L. Richie, P.F. Billingsley, B.K. Sim, E.R. James, S. Chakravarty, J.E. Epstein, K.E. Lyke, B. Mordmüller, P. Alonso, P.E. Duffy, O.K. Doumbo, R.W. Sauerwein, M. Tanner, S. Abdulla, P.G: Kremsner, R.A. Seder, S.L. Hoffman: Progress with Plasmodium falciparum sporozoite (PfSPZ)-based malaria vaccines. Vaccine 33(52): 7452-7461 (2015)

  • A.M. Rolle, P.T. Soboslay, G. Reischl, W.H. Hoffmann, B.J. Pichler, S. Wiehr: Evaluation of the Metabolic Activity of Echinococcus multilocularis in Rodents Using Positron Emission Tomography Tracers. Molecular Imaging and Biology 17(4): 512-520 (2015)

  • T. Rolling, T. Agbenyega, S. Krishna, P.G. Kremsner, J.P. Cramer: Delayed haemolysis after artesunate treatment of severe malaria - Review of the literature and perspective.
    Travel Medicine and Infectious Disease 13(2): 143-149 (2015). RTS,S Clinical Trials Partnership: Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial. Lancet. 386(9988): 31-45 (2015)

  • F. Schaumburg, A.S. Alabi, H. Kaba, B. Lell, K. Becker, M.P. Grobusch, P.G. Kremsner, A. Mellmann: Molecular characterization of Shigella spp. from patients in Gabon 2011-2013.
    Transactions of the Royal Society of Tropical Medicine and Hygiene 109(4): 275-279 (2015)

  • F. Schaumburg, M. Pauly, E. Anoh, A. Mossoun, L. Wiersma, G. Schubert, . Flammen, A.S. Alabi, J.J. Muyembe-Tamfum, M.P. Grobusch, S. Karhemere,C. Akoua-Koffi, E. Couacy-Hymann, P.G. Kremsner, A. Mellmann, K. Becker, F.H: Leendertz, G. Peters G: Staphylococcus aureus complex from animals and humans in three remote African regions. Clinical Microbiology and Infection 21(4): 345.e1-8 (2015)

  • Y. Schmiedel, G. Mombo-Ngoma, L.A. Labuda,J.J. Janse, B. de Gier, A.A. Adegnika, S. Issifou, P.G. Kremsner, H.H. Smits HH, M. Yazdanbakhsh: CD4+CD25hiFOXP3+ Regulatory T Cells and Cytokine Responses in Human Schistosomiasis before and after Treatment with Praziquantel. PLoS Neglected Tropical Diseases 9(8): e0003995 (2015)

  • J. Schmutzhard, P. Lackner, R. Helbok, H.V. Hurth, F.C. Aregger, V. Muigg, J. Kegele, S. Bunk, L. Oberhammer, N. Fischer, L. Pinggera, A. Otieno, B. Ogutu, T. Agbenyega, D. Ansong, A.A. Adegnika, S. Issifou, P. Zorowka, S. Krishna, B. Mordmüller,E. Schmutzhard, P. Kremsner: Severe malaria in children leads to a significant impairment of transitory otoacoustic emissions - a prospective multicenter cohort study. BMC Medicine 13(1): 125 (2015)

  • J. Schwille-Kiuntke, P. Enck, A.V. Polster, M. Gaile, P.G. Kremsner, P. Zanger: Postinfectious irritable bowel syndrome after travelers' diarrhea - a cohort study. Neurogastroenterology & Motility 27(8): 1147-1155 (2015)

  • E. Sicuri, S. Fernandes, E. Macete, R. González, G. Mombo-Ngoma, A. Massougbodgi, S. Abdulla, A. Kuwawenaruwa, A. Katana, M. Desai, M. Cot, M. Ramharter, P: Kremsner, L. Slustker, J. Aponte, K. Hanson, C. Menéndez: Economic evaluation of an alternative drug to sulfadoxine-pyrimethamine as intermittent preventive treatment of malaria in pregnancy. PLoS One 10(4): e0125072 (2015)

  • B.T. Sy, H.M. Nguyen, N.L. Toan, L.H. Song, H.V. Tong, C. Wolboldt, V.Q. Binh, P.G. Kremsner, T.P. Velavan, C.T. Bock: Identification of a natural intergenotypic recombinant hepatitis delta virus genotype 1 and 2 in Vietnamese HBsAg-positive patients. Journal of Viral Hepatitis 22 (1): 55-63 (2015)

  • D. Tappe, M. Sulyok, L. Rózsa, B. Muntau, A. Haeupler, I. Bodó, R. Hardi: Molecular Diagnosis of Abdominal Armillifer grandis Pentastomiasis in the Democratic Republic of Congo. Journal of Clinical Microbiology 53(7): 2362-2364 (2015)

  • H. Tong, L. Song, N. Hoan, B. Cuong, B. Sy, H. Son, D. Quyet, V. Binh V, P.G. Kremsner, C. Bock, T.P. Velavan, N. Toan: Soluble MICB protein levels and platelet counts during hepatitis B virus infection and response to hepatocellular carcinoma treatment. BMC Infectious Diseases 15(1): 25 (2015)

  • N.T. Trung, T.T. Hien, T.T. Huyen, D:T: Quyen, M.T: Binh, P.Q. Hoan, C.G. Meyer, T.P: Velavan, H. Song le: Simple multiplex PCR assays to detect common pathogens and associated genes encoding for acquired extended spectrum betalactamases (ESBL) or carbapenemases from surgical site specimens in Vietnam. Annals of Clinical Microbiology and Antimicrobials 14(1): 23 (2015)

  • N.K. Viebig, F. D'Alessio, S.J. Draper, B.K. Sim, B. Mordmüller, P.W. Bowyer, A.J. Luty, S. Jungbluth, C.E: Chitnis, A.V. Hill, P. Kremsner, A.G. Craig, C.H: Kocken, O. Leroy: Workshop report: Malaria vaccine development in Europe-preparing for the future. Vaccine 33(46): 6137-6144 (2015)

  • B.J. Visser, J. Meerveld-Gerrits, D. Kroon, J. Mougoula, R. Vingerling, E. Bache, J. Boersma, M. van Vugt, S.T: Agnandji, H. Kaur, M.P. Grobusch: Assessing the quality of anti-malarial drugs from Gabonese pharmacies using the MiniLab(®): a field study. Malaria Journal 14(1):273 (2015)

  • C. Wallmüller, B. Herold, F. Sterz, A. Makristathis, M. Ramharter M: Activity of antimicrobial drugs against bacterial pathogens under mild hypothermic conditions. American Journal of Emergency Medicine 33(10): 1445-1448 (2015)

  • B. Wangala, A. Vovor, R.G: Gantin, Y.F. Agbeko, C.J. Lechner, X. Huang, P.T. Soboslay, C. Köhler: Chemokine levels and parasite- and allergen-specific antibody responses in children and adults with severe or uncomplicated Plasmodium falciparum malaria. European Journal of Microbiology and Immunology 5(1): 131-141 (2015)

  • M.T. White, R. Verity, J.T. Griffin, K.P. Asante, S. Owusu-Agyei, B. Greenwood, C. Drakeley, S. Gesase, J. Lusingu, D. Ansong, S. Adjei, T. Agbenyega, B. Ogutu, L. Otieno, W. Otieno, S.T. Agnandji, B. Lell, P. Kremsner, I. Hoffman, F. Martinson, P. Kamthunzu, H. Tinto, I. Valea, H. Sorgho, M. Oneko, K. Otieno, M.J. Hamel, N. Salim, A. Mtoro, S. Abdulla, O. Aide, J. Sacarlal, J.J. Aponte, P. Njuguna, K. Marsh, P. Bejon, E.M. Riley, A.C. Ghani: Immunogenicity of the RTS,S/AS01 malaria vaccine and implications for duration of vaccine efficacy: secondary analysis of data from a phase 3 randomised controlled trial. Lancet Infectious Diseases 15(12) 1450-1458 (2015)

  • W.J. Wiersinga, E. Birnie, T.A. Weehuizen, A.S. Alabi, M.A. Huson, R.A. Huis in 't Veld, H.K. Mabala, G.K. Adzoda, Y. Raczynski-Henk, M. Esen, B. Lell, P.G. Kremsner, C.E. Visser, V. Wuthiekanun, S.J. Peacock, A. van der Ende, D. Limmathurotsakul, M.P. Grobusch MP. Clinical, environmental, and serologic surveillance studies of melioidosis in Gabon, 2012-2013. Emerging Infectious Diseases 21(1):40-47 (2015)

  • WorldWide Antimalarial Resistance Network (WWARN) Lumefantrine PK/PD Study Group: Artemether-lumefantrine treatment of uncomplicated Plasmodium falciparum malaria: a systematic review and meta-analysis of day 7 lumefantrine concentrations and therapeutic response using individual patient data. BMC Medicine 13: 227 (2015)

  • The WorldWide Antimalarial Resistance Network (WWARN) AS-AQ Study Group. The effect of dosing strategies on the therapeutic efficacy of artesunate-amodiaquine for uncomplicated malaria: a meta-analysis of individual patient data. BMC Medicine 13: 66 (2015)

  • Worldwide Antimalarial Resistance: The effect of dose on the antimalarial efficacy of artemether-lumefantrine: a systematic review and pooled analysis of individual patient data Lancet Infectious Diseases 15 (6): 692-702 (2015)

  • A Zumla, J. Chakaya, M. Hoelscher, F. Ntoumi, R. Rustomjee, C. Vilaplana, D. Yeboah-Manu, V. Rasolof, P. Munderi, N. Singh, E. Aklillu, N. Padayatchi, E. Macete, N. Kapata, M. Mulenga, G. Kibiki, S. Mfinanga, T. Nyirenda, L. Maboko, A. Garcia-Basteiro, N. Rakotosamimanana, M. Bates, P. Mwaba, K. Reither, S. Gagneux, S. Edwards, E. Mfinanga, S. Abdulla, P.J. Cardona, J.B. Russell, V. Gant, M. Noursadeghi, P. Elkington, M. Bonnet, C. Menendez, T.N. Dieye, B. Diarra, A. Maiga, S. Aseffa, S. Parida, C. Wejse, E. Petersen, P. Kaleebu, M. Oliver, G. Craig, T. Corrah, L. Tientcheu, M. Antonio, M. Rao, T.D. McHugh, A. Sheikh, G. Ippolito, G. Ramjee, S.H. Kaufmann, G. Churchyard, A. Steyn, M. Grobusch, I. Sanne, N. Martinson, R. Madansein, R.J. Wilkinson, B. Mayosi, M. Schito, R.S. Wallis, M. Maeurer: Towards host-directed therapies for tuberculosis. Nature Reviews Drug Discovery 14(8): 511-512 (2015)

  • A. Zumla, M. Maeurer M; Host-Directed Therapies Network (HDT-NET) Consortium; Host-Directed Therapies Network HDT-NET Consortium (Ntoumi): Host-Directed Therapies for Tackling Multi-Drug Resistant Tuberculosis: Learning From the Pasteur-Bechamp Debates. Clinical Infectious Diseases 61(9): 1432-1438 (2015)

Zertifikate und Verbände

Focus: Top Nationales Krankenhaus 2024

Die deutschen Universitätsklinika

Kooperation für Transparenz und Qualität im Gesundheitswesen

Qualitätspartnerschaft mit der PKV

Blauer Sterne Betrieb

Erfolgsfaktor Familie

Die Altersvorsorge für den Öffentlichen Dienst

Springe zum Hauptteil
Internationale Patienten Presse