Medizinische Klinik
Innere Medizin VII
Institut für Tropenmedizin, Reisemedizin, Humanparasitologie

Meral Esen is group leader for clinical trials and immunology at the Institute of Tropical Medicine in Tübingen. Her research focus is the safety and immunogenicity of experimental vaccines for the prevention of infectious diseases with special emphasis on the development of memory B-cells. Together with her partners in Gabon and other African countries she investigates neglected tropical diseases, in particular, the influence of co-factors like infections and Vitamin D on immune responses of affected individuals, especially in pregnant women and children.

• 1. Immune Responses to a Recombinant Glycoprotein E Herpes Zoster Vaccine in Adults Aged 50 Years or Older.
  Cunningham AL, Heineman TC, Lal H, Godeaux O, Chlibek R, Hwang SJ, McElhaney JE, Vesikari T, Andrews C, Choi WS, Esen M, Ikematsu H, Choma MK, Pauksens K, Ravault S, Salaun B, Schwarz TF, Smetana J, Abeele CV, Van den Steen P, Vastiau I, Weckx LY, Levin MJ; ZOE-50/70 Study Group.
  J Infect Dis. 2018 May 5;217(11):1750-1760. doi: 10.1093/infdis/jiy095.
  PMID:29529222
• 2. Evaluating dengue burden in Africa in passive fever surveillance and seroprevalence studies: protocol of field studies of the Dengue Vaccine Initiative.
  Lim JK, Carabali M, Lee JS, Lee KS, Namkung S, Lim SK, Ridde V, Fernandes J, Lell B, Matendechero SH, Esen M, Andia E, Oyembo N, Barro A, Bonnet E, Njenga SM, Agnandji ST, Yaro S, Alexander N, Yoon IK.
  BMJ Open. 2018 Jan 21;8(1):e017673. doi: 10.1136/bmjopen-2017-017673.
  PMID:29358421
• 3. Sterile protection against human malaria by chemoattenuated PfSPZ vaccine.
  Mordmüller B, Surat G, Lagler H, Chakravarty S, Ishizuka AS, Lalremruata A, Gmeiner M, Campo JJ, Esen M, Ruben AJ, Held J, Calle CL, Mengue JB, Gebru T, Ibáñez J, Sulyok M, James ER, Billingsley PF, Natasha KC, Manoj A, Murshedkar T, Gunasekera A, Eappen AG, Li T, Stafford RE, Li M, Felgner PL, Seder RA, Richie TL, Sim BK, Hoffman SL, Kremsner PG.
  Nature. 2017 Feb 23;542(7642):445-449. doi: 10.1038/nature21060. Epub
  2017 Feb 15.
  PMID: 28199305